Choline

"Choline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Descriptor ID	D002794
MeSH Number(s)	D02.033.100.291.211 D02.092.063.291.211 D02.092.877.883.333 D02.675.276.232
Concept/Terms	Choline Choline 2-Hydroxy-N,N,N-trimethylethanaminium Choline Citrate Choline Citrate Citrate, Choline Choline O-Sulfate Choline O-Sulfate Choline O Sulfate O-Sulfate, Choline Choline Hydroxide Choline Hydroxide Hydroxide, Choline Bursine Bursine Vidine Fagine Choline Bitartrate Choline Bitartrate Bitartrate, Choline Choline Chloride Choline Chloride Chloride, Choline

Below are MeSH descriptors whose meaning is more general than "Choline".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Ethanolamines [D02.033.100.291]
Choline [D02.033.100.291.211]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Ethanolamines [D02.092.063.291]
Choline [D02.092.063.291.211]
Quaternary Ammonium Compounds [D02.092.877]
Trimethyl Ammonium Compounds [D02.092.877.883]
Choline [D02.092.877.883.333]
Onium Compounds [D02.675]
Quaternary Ammonium Compounds [D02.675.276]
Choline [D02.675.276.232]

Below are MeSH descriptors whose meaning is related to "Choline".

Below are MeSH descriptors whose meaning is more specific than "Choline".

Choline
Platelet Activating Factor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Choline" by people in this website by year, and whether "Choline" was a major or minor topic of these publications.

Bar chart showing 17 publications over 11 distinct years, with a maximum of 4 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2002	0	4	4
2005	0	2	2
2008	1	0	1
2011	0	1	1
2015	0	1	1
2017	1	1	2
2018	1	1	2
2020	1	0	1
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "Choline" by people in Profiles.

Sawicki CM, Pacheco LS, Rivas-Tumanyan S, Cao Z, Haslam DE, Liang L, Tucker KL, Joshipura K, Bhupathiraju SN. Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts. Nutrients. 2024 Mar 27; 16(7).

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Kang WK, Florman JT, Araya A, Fox BW, Thackeray A, Schroeder FC, Walhout AJM, Alkema MJ. Vitamin B12 produced by gut bacteria modulates cholinergic signalling. Nat Cell Biol. 2024 Jan; 26(1):72-85.

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Tani H, Moxon-Emre I, Forde NJ, Neufeld NH, Bingham KS, Whyte EM, Meyers BS, Alexopoulos GS, Hoptman MJ, Rothschild AJ, Uchida H, Flint AJ, Mulsant BH, Voineskos AN. Brain metabolite levels in remitted psychotic depression with consideration of effects of antipsychotic medication. Brain Imaging Behav. 2024 Feb; 18(1):117-129.

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Caprarulo V, Erb SJ, Chandler TL, Zenobi MG, Barton BA, Staples CR, White HM. The effects of prepartum energy intake and peripartum rumen-protected choline supplementation on hepatic genes involved in glucose and lipid metabolism. J Dairy Sci. 2020 Dec; 103(12):11439-11448.

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Skinner M, Johnston BM, Liu Y, Hammer B, Selhorst R, Xenidou I, Perry SL, Emrick T. Synthesis of Zwitterionic Pluronic Analogs. Biomacromolecules. 2018 08 13; 19(8):3377-3389.

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Zenobi MG, Scheffler TL, Zuniga JE, Poindexter MB, Campagna SR, Castro Gonzalez HF, Farmer AT, Barton BA, Santos JEP, Staples CR. Feeding increasing amounts of ruminally protected choline decreased fatty liver in nonlactating, pregnant Holstein cows in negative energy status. J Dairy Sci. 2018 Jul; 101(7):5902-5923.

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Zenobi MG, Gardinal R, Zuniga JE, Dias ALG, Nelson CD, Driver JP, Barton BA, Santos JEP, Staples CR. Effects of supplementation with ruminally protected choline on performance of multiparous Holstein cows did not depend upon prepartum caloric intake. J Dairy Sci. 2018 Feb; 101(2):1088-1110.

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Marosfoi M, Clarencon F, Langan ET, King RM, Brooks OW, Tamura T, Wainwright JM, Gounis MJ, Vedantham S, Puri AS. Acute thrombus formation on phosphorilcholine surface modified flow diverters. J Neurointerv Surg. 2018 Apr; 10(4):406-411.

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Millard HR, Musani SK, Dibaba DT, Talegawkar SA, Taylor HA, Tucker KL, Bidulescu A. Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study. Eur J Nutr. 2018 Feb; 57(1):51-60.

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Csak T, Bala S, Lippai D, Kodys K, Catalano D, Iracheta-Vellve A, Szabo G. MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis. PLoS One. 2015; 10(6):e0129251.

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