Betaine

"Betaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)

Descriptor ID	D001622
MeSH Number(s)	D02.092.877.883.077 D02.675.276.125
Concept/Terms	Betaine Betaine Lycine Oxyneurine Glycine Betaine Betaine, Glycine Betaine Hydrochloride Betaine Hydrochloride Hydrochloride, Betaine Cystadane Cystadane Novobetaine Novobetaine Hepastyl Hepastyl C.B.B. C.B.B. Citrate de Bétaïne Beaufour Citrate de Bétaïne UPSA Citrate de Bétaïne UPSA Stea-16 Stea-16 Stea 16 Stea16 Acidin-Pepsin Acidin-Pepsin Acidin Pepsin AcidinPepsin Scorbo-bétaïne Scorbo-bétaïne Scorbo bétaïne Scorbobétaïne

Below are MeSH descriptors whose meaning is more general than "Betaine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amines [D02.092]
Quaternary Ammonium Compounds [D02.092.877]
Trimethyl Ammonium Compounds [D02.092.877.883]
Betaine [D02.092.877.883.077]
Onium Compounds [D02.675]
Quaternary Ammonium Compounds [D02.675.276]
Betaine [D02.675.276.125]

Below are MeSH descriptors whose meaning is more specific than "Betaine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Betaine" by people in this website by year, and whether "Betaine" was a major or minor topic of these publications.

Bar chart showing 10 publications over 5 distinct years, with a maximum of 3 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	2	0	2
2011	2	1	3
2013	1	0	1
2016	2	0	2
2024	1	1	2

Below are the most recent publications written about "Betaine" by people in Profiles.

Liu W, Liu K, Hu H, McClements DJ, Zhang Z, Zhang R, Qiu C, Long J, Chen G, Zou Y, Jin Z, Chen L. Modification of pea starch using ternary mixtures of natural crosslinking agents: Vanillin-chitosan-betaine and vanillin-gelatin-betaine. Int J Biol Macromol. 2024 Sep; 276(Pt 2):133949.

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Sawicki CM, Pacheco LS, Rivas-Tumanyan S, Cao Z, Haslam DE, Liang L, Tucker KL, Joshipura K, Bhupathiraju SN. Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts. Nutrients. 2024 Mar 27; 16(7).

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Millard HR, Musani SK, Dibaba DT, Talegawkar SA, Taylor HA, Tucker KL, Bidulescu A. Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study. Eur J Nutr. 2018 Feb; 57(1):51-60.

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Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Rib? S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C. Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice. Diabetes. 2016 04; 65(4):902-12.

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Liu P, Song J. Sulfobetaine as a zwitterionic mediator for 3D hydroxyapatite mineralization. Biomaterials. 2013 Mar; 34(10):2442-54.

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Colak S, Tew GN. Dual-functional ROMP-based betaines: effect of hydrophilicity and backbone structure on nonfouling properties. Langmuir. 2012 Jan 10; 28(1):666-75.

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Maddikeri RR, Colak S, Gido SP, Tew GN. Zwitterionic polymersomes in an ionic liquid: room temperature TEM characterization. Biomacromolecules. 2011 Oct 10; 12(10):3412-7.

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Seddon JM, Reynolds R, Shah HR, Rosner B. Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications. Ophthalmology. 2011 Jul; 118(7):1386-94.

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Strauss KA, Morton DH, Puffenberger EG, Hendrickson C, Robinson DL, Wagner C, Stabler SP, Allen RH, Chwatko G, Jakubowski H, Niculescu MD, Mudd SH. Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency. Mol Genet Metab. 2007 Jun; 91(2):165-75.

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Ignatova Z, Gierasch LM. Effects of osmolytes on protein folding and aggregation in cells. Methods Enzymol. 2007; 428:355-72.

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