Endocrine Disruptors

"Endocrine Disruptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.

Descriptor ID	D052244
MeSH Number(s)	D27.505.696.353 D27.888.141
Concept/Terms	Endocrine Disruptors Endocrine Disruptors Disruptors, Endocrine Endocrine Disrupting Chemicals Chemicals, Endocrine Disrupting Endocrine Disruptor Effect Endocrine Disruptor Effect Disruptor Effect, Endocrine Effect, Endocrine Disruptor Endocrine Disruptor Effects Disruptor Effects, Endocrine Effects, Endocrine Disruptor

Below are MeSH descriptors whose meaning is more general than "Endocrine Disruptors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Endocrine Disruptors [D27.505.696.353]
Toxic Actions [D27.888]
Endocrine Disruptors [D27.888.141]

Below are MeSH descriptors whose meaning is more specific than "Endocrine Disruptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endocrine Disruptors" by people in this website by year, and whether "Endocrine Disruptors" was a major or minor topic of these publications.

Bar chart showing 62 publications over 17 distinct years, with a maximum of 10 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	2	0	2
2007	2	2	4
2008	1	0	1
2009	3	0	3
2010	2	0	2
2012	2	1	3
2013	4	0	4
2014	5	0	5
2015	8	0	8
2016	10	0	10
2017	3	0	3
2018	4	0	4
2019	4	0	4
2020	3	1	4
2021	2	1	3
2022	1	0	1

Below are the most recent publications written about "Endocrine Disruptors" by people in Profiles.

Su Y, Santucci-Pereira J, Dang NM, Kanefsky J, Rahulkannan V, Hillegass M, Joshi S, Gurdogan H, Chen Z, Bessonneau V, Rudel R, Ser-Dolansky J, Schneider SS, Russo J. Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats. Int J Mol Sci. 2022 Jan 26; 23(3).

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Zoeller RT. Endocrine disrupting chemicals and thyroid hormone action. Adv Pharmacol. 2021; 92:401-417.

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Reeves KW, Vieyra G, Grimes NP, Meliker J, Jackson RD, Wactawski-Wende J, Wallace R, Zoeller RT, Bigelow C, Hankinson SE, Manson JE, Cauley JA, Calafat AM. Urinary Phthalate Biomarkers and Bone Mineral Density in Postmenopausal Women. J Clin Endocrinol Metab. 2021 06 16; 106(7):e2567-e2579.

View in: PubMed
Mogus JP, LaPlante CD, Bansal R, Matouskova K, Schneider BR, Daniele E, Silva SJ, Hagen MJ, Dunphy KA, Jerry DJ, Schneider SS, Vandenberg LN. Exposure to Propylparaben During Pregnancy and Lactation Induces Long-Term Alterations to the Mammary Gland in Mice. Endocrinology. 2021 06 01; 162(6).

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Gregory KJ, Morin SM, Kubosiak A, Ser-Dolansky J, Schalet BJ, Jerry DJ, Schneider SS. The use of patient-derived breast tissue explants to study macrophage polarization and the effects of environmental chemical exposure. Immunol Cell Biol. 2020 11; 98(10):883-896.

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Heindel JJ, Belcher S, Flaws JA, Prins GS, Ho SM, Mao J, Patisaul HB, Ricke W, Rosenfeld CS, Soto AM, Vom Saal FS, Zoeller RT. Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies. Reprod Toxicol. 2020 12; 98:29-60.

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Vandenberg LN, Prins GS, Patisaul HB, Zoeller RT. The Use and Misuse of Historical Controls in Regulatory Toxicology: Lessons from the CLARITY-BPA Study. Endocrinology. 2020 05 01; 161(5).

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Kortenkamp A, Axelstad M, Baig AH, Bergman ?, Bornehag CG, Cenijn P, Christiansen S, Demeneix B, Derakhshan A, Fini JB, Fr?drich C, Hamers T, Hellwig L, K?hrle J, Korevaar TIM, Lindberg J, Martin O, Meima ME, Mergenthaler P, Nikolov N, Du Pasquier D, Peeters RP, Platzack B, Ramh?j L, Remaud S, Renko K, Scholze M, Stachelscheid H, Svingen T, Wagenaars F, Wedebye EB, Zoeller RT. Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals-The ATHENA Project. Int J Mol Sci. 2020 Apr 28; 21(9).

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La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinol. 2020 01; 16(1):45-57.

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Titus L, Hatch EE, Palmer JR, Huo D, Strohsnitter WC, Adam E, Ricker W, Hyer M, Hoover RN, Troisi R. Prenatal Diethylstilbestrol Exposure and Risk of Depression in Women and Men. Epidemiology. 2019 09; 30(5):679-686.

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