E2F1 Transcription Factor
"E2F1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
Descriptor ID |
D050687
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MeSH Number(s) |
D12.644.360.024.328.049 D12.776.157.057.158.049 D12.776.476.024.420.049 D12.776.660.769.049 D12.776.930.211.500
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Concept/Terms |
E2F1 Transcription Factor- E2F1 Transcription Factor
- Transcription Factor, E2F1
- Transcription Factor E2F-1
- Transcription Factor E2F 1
- E2F Transcription Factor 1 Protein
- Retinoblastoma-Associated Protein 1
- Retinoblastoma Associated Protein 1
- Retinoblastoma Binding Protein 3
- E2F-1 Transcription Factor
- Transcription Factor, E2F-1
- Transcription Factor E2F1
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Below are MeSH descriptors whose meaning is more general than "E2F1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F1 Transcription Factor".
This graph shows the total number of publications written about "E2F1 Transcription Factor" by people in this website by year, and whether "E2F1 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 |
1998 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2006 | 2 | 1 | 3 |
2008 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F1 Transcription Factor" by people in Profiles.
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Ghari F, Quirke AM, Munro S, Kawalkowska J, Picaud S, McGouran J, Subramanian V, Muth A, Williams R, Kessler B, Thompson PR, Fillipakopoulos P, Knapp S, Venables PJ, La Thangue NB. Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response. Sci Adv. 2016 Feb; 2(2):e1501257.
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Zhang W, Chen H, Chen Y, Liu J, Wang X, Yu X, Chen JJ, Zhao W. Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1. Oncotarget. 2015 Mar 10; 6(7):5253-62.
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E X, Pickering MT, Debatis M, Castillo J, Lagadinos A, Wang S, Lu S, Kowalik TF. An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus. PLoS Pathog. 2011 May; 7(5):e1001342.
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Pickering MT, Stadler BM, Kowalik TF. miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene. 2009 Jan 08; 28(1):140-5.
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Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. FEBS J. 2006 Dec; 273(24):5714-23.
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Pickering MT, Kowalik TF. Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation. Oncogene. 2006 Feb 02; 25(5):746-55.
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Frame FM, Rogoff HA, Pickering MT, Cress WD, Kowalik TF. E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts. Oncogene. 2006 Jun 01; 25(23):3258-66.
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Rogoff HA, Kowalik TF. Life, death and E2F: linking proliferation control and DNA damage signaling via E2F1. Cell Cycle. 2004 Jul; 3(7):845-6.
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Rogoff HA, Pickering MT, Frame FM, Debatis ME, Sanchez Y, Jones S, Kowalik TF. Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2. Mol Cell Biol. 2004 Apr; 24(7):2968-77.
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Carey JL, Sasur LM, Kawakubo H, Gupta V, Christian B, Bailey PM, Maheswaran S. Mutually antagonistic effects of androgen and activin in the regulation of prostate cancer cell growth. Mol Endocrinol. 2004 Mar; 18(3):696-707.