Bone Morphogenetic Proteins

"Bone Morphogenetic Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

Descriptor ID	D019485
MeSH Number(s)	D12.644.276.954.200 D12.776.467.942.200 D23.529.942.200
Concept/Terms	Bone Morphogenetic Proteins Bone Morphogenetic Proteins Morphogenetic Proteins, Bone Bone Morphogenetic Protein Morphogenetic Protein, Bone

Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
TGF-beta Superfamily Proteins [D12.644.276.954]
Bone Morphogenetic Proteins [D12.644.276.954.200]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
TGF-beta Superfamily Proteins [D12.776.467.942]
Bone Morphogenetic Proteins [D12.776.467.942.200]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
TGF-beta Superfamily Proteins [D23.529.942]
Bone Morphogenetic Proteins [D23.529.942.200]

Below are MeSH descriptors whose meaning is related to "Bone Morphogenetic Proteins".

Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Morphogenetic Proteins" by people in this website by year, and whether "Bone Morphogenetic Proteins" was a major or minor topic of these publications.

Bar chart showing 58 publications over 24 distinct years, with a maximum of 6 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	1	1	2
2002	0	2	2
2003	2	1	3
2004	1	3	4
2005	4	1	5
2006	5	1	6
2007	3	2	5
2008	4	0	4
2009	1	0	1
2010	3	0	3
2011	1	2	3
2012	2	0	2
2013	1	0	1
2014	1	0	1
2015	0	1	1
2016	0	2	2
2017	1	2	3
2018	1	0	1
2019	1	2	3
2020	2	0	2
2021	1	0	1
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "Bone Morphogenetic Proteins" by people in Profiles.

Najafi S, Barasa L, Frianela JMJ, Alkhamisy JH, Yoganathan S, Perron JC. Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells. Front Biosci (Landmark Ed). 2023 10 27; 28(10):268.

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Najafi S, Barasa L, Huang SY, Yoganathan S, Perron JC. Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling. Sci Rep. 2022 07 15; 12(1):12146.

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Gramann AK, Frantz WT, Dresser K, Gomes CBF, Lian CG, Deng A, Ceol CJ. BMP Signaling Promotes Neural Crest Identity and?Accelerates Melanoma Onset. J Invest Dermatol. 2021 08; 141(8):2067-2070.e1.

View in: PubMed
Brown ML, Schneyer A. A Decade Later: Revisiting the TGF? Family's Role in Diabetes. Trends Endocrinol Metab. 2021 01; 32(1):36-47.

View in: PubMed
Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT. Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. Sci Rep. 2020 03 12; 10(1):4561.

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Gramann AK, Venkatesan AM, Guerin M, Ceol CJ. Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling. Elife. 2019 12 23; 8.

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Zhang B, Skelly JD, Maalouf JR, Ayers DC, Song J. Multifunctional scaffolds for facile implantation, spontaneous fixation, and accelerated long bone regeneration in rodents. Sci Transl Med. 2019 07 24; 11(502).

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Vieira WA, Wells KM, Raymond MJ, De Souza L, Garcia E, McCusker CD. FGF, BMP, and RA signaling are sufficient for the induction of complete limb regeneration from non-regenerating wounds on Ambystoma mexicanum limbs. Dev Biol. 2019 07 15; 451(2):146-157.

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Palaria A, Angelo JR, Guertin TM, Mager J, Tremblay KD. Patterning of the hepato-pancreatobiliary boundary by BMP reveals heterogeneity within the murine liver bud. Hepatology. 2018 07; 68(1):274-288.

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Venkatesan AM, Vyas R, Gramann AK, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes CBF, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. J Clin Invest. 2018 01 02; 128(1):294-308.

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