 Laminin
"Laminin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
| Descriptor ID |
D007797
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| MeSH Number(s) |
D12.776.395.550.530 D12.776.543.550.500 D12.776.860.300.675
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| Concept/Terms |
Laminin- Laminin
- Glycoprotein GP-2
- Glycoprotein GP 2
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Below are MeSH descriptors whose meaning is more general than "Laminin".
Below are MeSH descriptors whose meaning is more specific than "Laminin".
This graph shows the total number of publications written about "Laminin" by people in this website by year, and whether "Laminin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 0 | 2 | 2 | | 1990 | 4 | 1 | 5 | | 1991 | 2 | 0 | 2 | | 1992 | 0 | 1 | 1 | | 1993 | 2 | 0 | 2 | | 1994 | 2 | 1 | 3 | | 1995 | 0 | 2 | 2 | | 1996 | 1 | 4 | 5 | | 1997 | 3 | 1 | 4 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2003 | 1 | 3 | 4 | | 2004 | 1 | 3 | 4 | | 2005 | 1 | 2 | 3 | | 2006 | 1 | 6 | 7 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 2 | 2 | 4 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 3 | 1 | 4 |
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Below are the most recent publications written about "Laminin" by people in Profiles.
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Liu YB, Tewari A, Salameh J, Arystarkhova E, Hampton TG, Brashear A, Ozelius LJ, Khodakhah K, Sweadner KJ. A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin ß1 subunit, Lamb1. Elife. 2015 Dec 24; 4.
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Vohra R, Accorsi A, Kumar A, Walter G, Girgenrath M. Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A). PLoS One. 2015; 10(9):e0138254.
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Ross JB, Huh D, Noble LB, Tavazoie SF. Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer. Nat Cell Biol. 2015 May; 17(5):651-64.
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Hyldahl RD, Nelson B, Xin L, Welling T, Groscost L, Hubal MJ, Chipkin S, Clarkson PM, Parcell AC. Extracellular matrix remodeling and its contribution to protective adaptation following lengthening contractions in human muscle. FASEB J. 2015 Jul; 29(7):2894-904.
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Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6Bß1 integrin to sustain breast cancer stem cells. Genes Dev. 2015 Jan 01; 29(1):1-6.
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Larson AR, Lee CW, Lezcano C, Zhan Q, Huang J, Fischer AH, Murphy GF. Melanoma spheroid formation involves laminin-associated vasculogenic mimicry. Am J Pathol. 2014 Jan; 184(1):71-8.
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Yamauchi J, Kumar A, Duarte L, Mehuron T, Girgenrath M. Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A. Hum Mol Genet. 2013 Nov 1; 22(21):4306-17.
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Goel HL, Pursell B, Standley C, Fogarty K, Mercurio AM. Neuropilin-2 regulates a6ß1 integrin in the formation of focal adhesions and signaling. J Cell Sci. 2012 Jan 15; 125(Pt 2):497-506.
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Scully S, Yan W, Bentley B, Cao QJ, Shao R. Inhibitory activity of YKL-40 in mammary epithelial cell differentiation and polarization induced by lactogenic hormones: a role in mammary tissue involution. PLoS One. 2011; 6(10):e25819.
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Francescone RA, Faibish M, Shao R. A Matrigel-based tube formation assay to assess the vasculogenic activity of tumor cells. J Vis Exp. 2011 Sep 07; (55).
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