Adenosine Diphosphate Ribose

"Adenosine Diphosphate Ribose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins.

Descriptor ID	D000246
MeSH Number(s)	D03.633.100.759.646.138.124.070.125 D09.408.620.569.070.125 D13.695.667.138.124.070.125 D13.695.827.068.124.070.125 D13.695.827.708.070.125
Concept/Terms	Adenosine Diphosphate Ribose Adenosine Diphosphate Ribose Diphosphate Ribose, Adenosine Ribose, Adenosine Diphosphate ADP-Ribose ADP Ribose Ribose, ADP ADPribose Adenosine 5'-Diphosphoribose 5'-Diphosphoribose, Adenosine Adenosine 5' Diphosphoribose Adenosine Diphosphoribose Diphosphoribose, Adenosine

Below are MeSH descriptors whose meaning is more general than "Adenosine Diphosphate Ribose".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Adenosine Diphosphate [D03.633.100.759.646.138.124]
Adenosine Diphosphate Sugars [D03.633.100.759.646.138.124.070]
Adenosine Diphosphate Ribose [D03.633.100.759.646.138.124.070.125]
Carbohydrates [D09]
Glycosides [D09.408]
Nucleotides [D09.408.620]
Nucleoside Diphosphate Sugars [D09.408.620.569]
Adenosine Diphosphate Sugars [D09.408.620.569.070]
Adenosine Diphosphate Ribose [D09.408.620.569.070.125]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Adenosine Diphosphate [D13.695.667.138.124]
Adenosine Diphosphate Sugars [D13.695.667.138.124.070]
Adenosine Diphosphate Ribose [D13.695.667.138.124.070.125]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Adenosine Diphosphate [D13.695.827.068.124]
Adenosine Diphosphate Sugars [D13.695.827.068.124.070]
Adenosine Diphosphate Ribose [D13.695.827.068.124.070.125]
Nucleoside Diphosphate Sugars [D13.695.827.708]
Adenosine Diphosphate Sugars [D13.695.827.708.070]
Adenosine Diphosphate Ribose [D13.695.827.708.070.125]

Below are MeSH descriptors whose meaning is related to "Adenosine Diphosphate Ribose".

Below are MeSH descriptors whose meaning is more specific than "Adenosine Diphosphate Ribose".

Adenosine Diphosphate Ribose
Cyclic ADP-Ribose
O-Acetyl-ADP-Ribose

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adenosine Diphosphate Ribose" by people in this website by year, and whether "Adenosine Diphosphate Ribose" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	1	2
2001	0	1	1
2006	0	1	1
2018	0	1	1
2019	0	1	1
2020	0	1	1
2021	0	1	1
2026	0	1	1

Below are the most recent publications written about "Adenosine Diphosphate Ribose" by people in Profiles.

Sandmann M, Tajdar S, Sander S, Ruiz Carrillo D, Ganter B, Fischer C, Ocenas M, Etzold S, Pekarek N, Berger J, Meister TL, Selisko B, Canard B, Watt JM, Baszczy?ski O, Potter BV, Garcia Alai M, Tidow H, Pfefferle S, Meier C, Fliegert R. Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2. Nat Commun. 2026 07 27; 17(1).

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Rish AD, Shen Z, Fu TM. It takes two to Tango: Two gates orchestrate the opening of human TRPM2. Cell Calcium. 2022 01; 101:102523.

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Loring HS, Icso JD, Nemmara VV, Thompson PR. Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1. Biochemistry. 2020 03 03; 59(8):933-942.

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Xia S, Wang L, Fu TM, Wu H. Mechanism of TRPM2 channel gating revealed by cryo-EM. FEBS J. 2019 09; 286(17):3333-3339.

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Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science. 2018 12 21; 362(6421).

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Morrison AR, Moss J, Stevens LA, Evans JE, Farrell C, Merithew E, Lambright DG, Greiner DL, Mordes JP, Rossini AA, Bortell R. ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose). J Biol Chem. 2006 Nov 03; 281(44):33363-72.

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Bortell R, Moss J, McKenna RC, Rigby MR, Niedzwiecki D, Stevens LA, Patton WA, Mordes JP, Greiner DL, Rossini AA. Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. J Immunol. 2001 Aug 15; 167(4):2049-59.

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Aepfelbacher M, Essler M, Huber E, Sugai M, Weber PC. Bacterial toxins block endothelial wound repair. Evidence that Rho GTPases control cytoskeletal rearrangements in migrating endothelial cells. Arterioscler Thromb Vasc Biol. 1997 Sep; 17(9):1623-9.

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Moss J, Stevens LA, Cavanaugh E, Okazaki IJ, Bortell R, Kanaitsuka T, Mordes JP, Greiner DL, Rossini AA. Characterization of mouse Rt6.1 NAD:arginine ADP-ribosyltransferase. J Biol Chem. 1997 Feb 14; 272(7):4342-6.

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Bortell R, Rigby M, Stevens L, Moss J, Kanaitsuka T, Mordes J, Greiner D, Rossini A. Mouse RT6 locus 1 and rat RT6.2 are NAD+. Arginine ADP-ribosyltransferases with auto-ADP-ribosylation activity. Adv Exp Med Biol. 1997; 419:169-73.

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