"Chromogranin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
| Descriptor ID |
D053379
|
| MeSH Number(s) |
D12.776.631.199.249
|
| Concept/Terms |
Chromogranin A- Chromogranin A
- Parathyroid Secretory Protein
- Secretory Protein, Parathyroid
- CHGA Protein
- Secretory Protein I, Parathyroid Gland
|
Below are MeSH descriptors whose meaning is more general than "Chromogranin A".
Below are MeSH descriptors whose meaning is more specific than "Chromogranin A".
This graph shows the total number of publications written about "Chromogranin A" by people in this website by year, and whether "Chromogranin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2010 | 1 | 2 | 3 |
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Below are the most recent publications written about "Chromogranin A" by people in Profiles.
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Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. J Neural Transm (Vienna). 2010 Aug; 117(8):919-47.
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D'Agostino M, Cinelli C, Willard R, Hofmann J, Jellinek N, Robinson-Bostom L. Epidermotropic Merkel cell carcinoma: a case series with histopathologic examination. J Am Acad Dermatol. 2010 Mar; 62(3):463-8.
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Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31.
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Khan A, Tischler AS, Patwardhan NA, DeLellis RA. Calcitonin immunoreactivity in neoplastic and hyperplastic parathyroid glands: an immunohistochemical study. Endocr Pathol. 2003; 14(3):249-55.