"TATA-Box Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.
| Descriptor ID |
D035181
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| MeSH Number(s) |
D12.776.260.775.374 D12.776.260.775.875.750.500 D12.776.930.930.374 D12.776.930.930.875.750.500
|
| Concept/Terms |
TATA-Box Binding Protein- TATA-Box Binding Protein
- TATA Box Binding Protein
- Transcription Factor TBP
- TATA-Box-Binding Protein
- RNA Polymerase II TATA-Binding Protein
- RNA Polymerase II TATA Binding Protein
- TATA-Binding Protein
- TATA Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "TATA-Box Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "TATA-Box Binding Protein".
This graph shows the total number of publications written about "TATA-Box Binding Protein" by people in this website by year, and whether "TATA-Box Binding Protein" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "TATA-Box Binding Protein" by people in Profiles.
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Xue Y, Pradhan SK, Sun F, Chronis C, Tran N, Su T, Van C, Vashisht A, Wohlschlegel J, Peterson CL, Timmers HTM, Kurdistani SK, Carey MF. Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Mol Cell. 2017 Aug 17; 67(4):594-607.e4.
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Maston GA, Zhu LJ, Chamberlain L, Lin L, Fang M, Green MR. Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. Elife. 2012 Nov 13; 1:e00068.
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Hart DO, Santra MK, Raha T, Green MR. Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis. Dev Dyn. 2009 Oct; 238(10):2540-9.
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Hart DO, Raha T, Lawson ND, Green MR. Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature. 2007 Dec 13; 450(7172):1082-5.
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Fran?ois A, Guilbaud M, Awedikian R, Chadeuf G, Moullier P, Salvetti A. The cellular TATA binding protein is required for rep-dependent replication of a minimal adeno-associated virus type 2 p5 element. J Virol. 2005 Sep; 79(17):11082-94.
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Raha T, Cheng SW, Green MR. HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs. PLoS Biol. 2005 Feb; 3(2):e44.
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Biswas D, Imbalzano AN, Eriksson P, Yu Y, Stillman DJ. Role for Nhp6, Gcn5, and the Swi/Snf complex in stimulating formation of the TATA-binding protein-TFIIA-DNA complex. Mol Cell Biol. 2004 Sep; 24(18):8312-21.
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Friedman JS, Khanna H, Swain PK, Denicola R, Cheng H, Mitton KP, Weber CH, Hicks D, Swaroop A. The minimal transactivation domain of the basic motif-leucine zipper transcription factor NRL interacts with TATA-binding protein. J Biol Chem. 2004 Nov 05; 279(45):47233-41.
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Li XY, Bhaumik SR, Zhu X, Li L, Shen WC, Dixit BL, Green MR. Selective recruitment of TAFs by yeast upstream activating sequences. Implications for eukaryotic promoter structure. Curr Biol. 2002 Jul 23; 12(14):1240-4.
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Virbasius CM, Holstege FC, Young RA, Green MR. Promoter-specific activation defects by a novel yeast TBP mutant compromised for TFIIB interaction. Curr Biol. 2001 Nov 13; 11(22):1794-8.