Transcription Factor TFIID
"Transcription Factor TFIID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major sequence-specific DNA-binding component involved in the activation of transcription of RNA POLYMERASE II. It was originally described as a complex of TATA-BOX BINDING PROTEIN and TATA-BINDING PROTEIN ASSOCIATED FACTORS. It is now know that TATA BOX BINDING PROTEIN-LIKE PROTEINS may take the place of TATA-box binding protein in the complex.
Descriptor ID |
D035362
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MeSH Number(s) |
D12.776.260.775.875.750 D12.776.930.930.875.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIID".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIID".
This graph shows the total number of publications written about "Transcription Factor TFIID" by people in this website by year, and whether "Transcription Factor TFIID" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2010 | 2 | 0 | 2 |
2017 | 0 | 1 | 1 |
2022 | 1 | 0 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIID" by people in Profiles.
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He XD, Phillips S, Hioki K, Majhi PD, Babbitt C, Tremblay KD, Pobezinsky LA, Mager J. TATA-binding associated factors have distinct roles during early mammalian development. Dev Biol. 2024 Jul; 511:53-62.
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Gura MA, Relovsk? S, Abt KM, Seymour KA, Wu T, Kaya H, Turner JMA, Fazzio TG, Freiman RN. TAF4b transcription networks regulating early oocyte differentiation. Development. 2022 02 01; 149(3).
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Xue Y, Pradhan SK, Sun F, Chronis C, Tran N, Su T, Van C, Vashisht A, Wohlschlegel J, Peterson CL, Timmers HTM, Kurdistani SK, Carey MF. Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Mol Cell. 2017 Aug 17; 67(4):594-607.e4.
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Pistis G, Okonkwo SU, Traglia M, Sala C, Shin SY, Masciullo C, Buetti I, Massacane R, Mangino M, Thein SL, Spector TD, Ganesh S, Pirastu N, Gasparini P, Soranzo N, Camaschella C, Hart D, Green MR, Toniolo D. Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans. PLoS One. 2013; 8(7):e69206.
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Carey MF, Peterson CL, Smale ST. Magnesium-agarose electrophoretic mobility shift assay (EMSA) of transcription factor IID binding to DNA. Cold Spring Harb Protoc. 2010 Nov 01; 2010(11):pdb.prot5514.
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Carey MF, Peterson CL, Smale ST. Purification of epitope-tagged transcription factor IID. Cold Spring Harb Protoc. 2010 Jul 01; 2010(7):pdb.prot5450.
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Yagi Y, Ip YT. Helicase89B is a Mot1p/BTAF1 homologue that mediates an antimicrobial response in Drosophila. EMBO Rep. 2005 Nov; 6(11):1088-94.
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Walker AK, Shi Y, Blackwell TK. An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription. J Biol Chem. 2004 Apr 09; 279(15):15339-47.
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Persengiev SP, Zhu X, Dixit BL, Maston GA, Kittler EL, Green MR. TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14887-91.
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Reese JC, Green MR. Functional analysis of TFIID components using conditional mutants. Methods Enzymol. 2003; 370:415-30.