A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

Descriptor ID	D013004
MeSH Number(s)	D06.472.699.327.700.875 D06.472.699.587.780 D12.644.400.400.700.875 D12.644.548.365.700.875 D12.644.548.586.780 D12.776.631.650.405.700.875
Concept/Terms	Somatostatin Somatostatin SRIH-14 Somatotropin Release-Inhibiting Factor Somatotropin Release Inhibiting Factor Cyclic Somatostatin Somatostatin-14 Somatostatin 14 Somatotropin Release-Inhibiting Hormone Somatotropin Release Inhibiting Hormone Somatostatin, Cyclic Stilamin Stilamin Somatofalk Somatofalk

Below are MeSH descriptors whose meaning is more general than "Somatostatin".

Below are MeSH descriptors whose meaning is related to "Somatostatin".

Below are MeSH descriptors whose meaning is more specific than "Somatostatin".