Islet Amyloid Polypeptide
"Islet Amyloid Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
| Descriptor ID |
D058228
|
| MeSH Number(s) |
D06.472.699.587.334 D12.644.548.586.234 D12.776.049.407.500
|
| Concept/Terms |
Islet Amyloid Polypeptide- Islet Amyloid Polypeptide
- Amyloid Polypeptide, Islet
- Polypeptide, Islet Amyloid
- Pancreatic Amylin
- Amylin, Pancreatic
- IAPP Protein
- Insulinoma Amyloid Polypeptide
- Amyloid Polypeptide, Insulinoma
- Polypeptide, Insulinoma Amyloid
- Amlintide
- Amylin
|
Below are MeSH descriptors whose meaning is more general than "Islet Amyloid Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Islet Amyloid Polypeptide".
This graph shows the total number of publications written about "Islet Amyloid Polypeptide" by people in this website by year, and whether "Islet Amyloid Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Islet Amyloid Polypeptide" by people in Profiles.
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Aftabizadeh M, Tatarek-Nossol M, Andreetto E, El Bounkari O, Kipp M, Beyer C, Latz E, Bernhagen J, Kapurniotu A. Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic. ACS Chem Neurosci. 2019 08 21; 10(8):3703-3717.
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Shalev A, Pise-Masison CA, Radonovich M, Hoffmann SC, Hirshberg B, Brady JN, Harlan DM. Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway. Endocrinology. 2002 Sep; 143(9):3695-8.