"Cell Dedifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reverse developmental process in which terminally differentiated cells with specialized functions revert back to a less differentiated stage within their own CELL LINEAGE.
Descriptor ID |
D054337
|
MeSH Number(s) |
G04.148
|
Concept/Terms |
Cell Dedifferentiation- Cell Dedifferentiation
- Cell Dedifferentiations
- Dedifferentiations, Cell
- Dedifferentiation, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Dedifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Dedifferentiation".
This graph shows the total number of publications written about "Cell Dedifferentiation" by people in this website by year, and whether "Cell Dedifferentiation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cell Dedifferentiation" by people in Profiles.
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Sandiford OA, Donnelly RJ, El-Far MH, Burgmeyer LM, Sinha G, Pamarthi SH, Sherman LS, Ferrer AI, DeVore DE, Patel SA, Naaldijk Y, Alonso S, Barak P, Bryan M, Ponzio NM, Narayanan R, Etchegaray JP, Kumar R, Rameshwar P. Mesenchymal Stem Cell-Secreted Extracellular Vesicles Instruct Stepwise Dedifferentiation of Breast Cancer Cells into Dormancy at the Bone Marrow Perivascular Region. Cancer Res. 2021 03 15; 81(6):1567-1582.
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Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA. Reversal of ? cell de-differentiation by a small molecule inhibitor of the TGF? pathway. Elife. 2014 Sep 16; 3:e02809.
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Davies CC, Harvey E, McMahon RF, Finegan KG, Connor F, Davis RJ, Tuveson DA, Tournier C. Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Res. 2014 Jun 15; 74(12):3344-56.
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Li Z, Yang CS, Nakashima K, Rana TM. Small RNA-mediated regulation of iPS cell generation. EMBO J. 2011 Mar 02; 30(5):823-34.
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Pereira BP, Zhou Y, Gupta A, Leong DT, Aung KZ, Ling L, Pho RW, Galindo M, Salto-Tellez M, Stein GS, Cool SM, van Wijnen AJ, Nathan SS. Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). J Cell Physiol. 2009 Dec; 221(3):778-88.
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Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, Leibel RL, Melton DA. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15768-73.