Vascular Endothelial Growth Factor Receptor-3
"Vascular Endothelial Growth Factor Receptor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult lymphatic endothelium. VEGFR-3 preferentially binds the vascular endothelial growth factor C and vascular endothelial growth factor D and may be involved in the control of lymphangiogenesis.
Descriptor ID |
D040321
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.950.300 D12.776.543.750.630.750.300 D12.776.543.750.750.400.910.300
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor Receptor-3".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor Receptor-3".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor Receptor-3" by people in this website by year, and whether "Vascular Endothelial Growth Factor Receptor-3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2015 | 1 | 1 | 2 |
2016 | 0 | 2 | 2 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor Receptor-3" by people in Profiles.
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Jerafi-Vider A, Bassi I, Moshe N, Tevet Y, Hen G, Splittstoesser D, Shin M, Lawson ND, Yaniv K. VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells. Cell Rep. 2021 06 15; 35(11):109255.
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Shin M, Male I, Beane TJ, Villefranc JA, Kok FO, Zhu LJ, Lawson ND. Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors. Development. 2016 10 15; 143(20):3785-3795.
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Shin M, Beane TJ, Quillien A, Male I, Zhu LJ, Lawson ND. Vegfa signals through ERK to promote angiogenesis, but not artery differentiation. Development. 2016 10 15; 143(20):3796-3805.
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Wang W, Sukamtoh E, Xiao H, Zhang G. Curcumin inhibits lymphangiogenesis in vitro and in vivo. Mol Nutr Food Res. 2015 Dec; 59(12):2345-54.
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Cornejo KM, Deng A, Wu H, Cosar EF, Khan A, St Cyr M, Tomaszewicz K, Dresser K, O'Donnell P, Hutchinson L. The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast. Hum Pathol. 2015 Jun; 46(6):868-75.
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Nicoli S, Knyphausen CP, Zhu LJ, Lakshmanan A, Lawson ND. miR-221 is required for endothelial tip cell behaviors during vascular development. Dev Cell. 2012 Feb 14; 22(2):418-29.
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Dadras SS, Skrzypek A, Nguyen L, Shin JW, Schulz MM, Arbiser J, Mihm MC, Detmar M. Prox-1 promotes invasion of kaposiform hemangioendotheliomas. J Invest Dermatol. 2008 Dec; 128(12):2798-806.
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Siekmann AF, Lawson ND. Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature. 2007 Feb 15; 445(7129):781-4.
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Covassin LD, Villefranc JA, Kacergis MC, Weinstein BM, Lawson ND. Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish. Proc Natl Acad Sci U S A. 2006 Apr 25; 103(17):6554-9.
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Zhang X, Wang JF, Chandran B, Persaud K, Pytowski B, Fingeroth J, Groopman JE. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. J Biol Chem. 2005 Jul 15; 280(28):26216-24.