 Cytotoxicity, Immunologic
"Cytotoxicity, Immunologic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.
| Descriptor ID |
D003602
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| MeSH Number(s) |
G12.425.270
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytotoxicity, Immunologic".
Below are MeSH descriptors whose meaning is more specific than "Cytotoxicity, Immunologic".
This graph shows the total number of publications written about "Cytotoxicity, Immunologic" by people in this website by year, and whether "Cytotoxicity, Immunologic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 2 | 3 | | 1981 | 4 | 3 | 7 | | 1982 | 6 | 5 | 11 | | 1983 | 0 | 3 | 3 | | 1984 | 2 | 1 | 3 | | 1985 | 3 | 2 | 5 | | 1986 | 1 | 5 | 6 | | 1987 | 0 | 1 | 1 | | 1988 | 1 | 1 | 2 | | 1989 | 1 | 2 | 3 | | 1990 | 1 | 0 | 1 | | 1991 | 0 | 4 | 4 | | 1992 | 2 | 3 | 5 | | 1993 | 2 | 1 | 3 | | 1994 | 0 | 2 | 2 | | 1995 | 1 | 2 | 3 | | 1996 | 3 | 2 | 5 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 3 | 4 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 3 | 5 | | 2001 | 0 | 3 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 2 | 3 | 5 | | 2005 | 3 | 2 | 5 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 4 | 5 | | 2008 | 2 | 2 | 4 | | 2009 | 2 | 3 | 5 | | 2010 | 4 | 3 | 7 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cytotoxicity, Immunologic" by people in Profiles.
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Ruscetti M, Leibold J, Bott MJ, Fennell M, Kulick A, Salgado NR, Chen CC, Ho YJ, Sanchez-Rivera FJ, Feucht J, Baslan T, Tian S, Chen HA, Romesser PB, Poirier JT, Rudin CM, de Stanchina E, Manchado E, Sherr CJ, Lowe SW. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018 12 21; 362(6421):1416-1422.
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Hatfield SD, Daniels KA, O'Donnell CL, Waggoner SN, Welsh RM. Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity. Virology. 2018 06; 519:131-144.
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Mitchell MJ, King MR. Unnatural killer cells to prevent bloodborne metastasis: inspiration from biology and engineering. Expert Rev Anticancer Ther. 2014 Jun; 14(6):641-4.
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Mishra R, Polic B, Welsh RM, Szomolanyi-Tsuda E. Inflammatory cytokine-mediated evasion of virus-induced tumors from NK cell control. J Immunol. 2013 Jul 15; 191(2):961-70.
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Cho JL, Roche MI, Sandall B, Brass AL, Seed B, Xavier RJ, Medoff BD. Enhanced Tim3 activity improves survival after influenza infection. J Immunol. 2012 Sep 15; 189(6):2879-89.
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Liddy N, Bossi G, Adams KJ, Lissina A, Mahon TM, Hassan NJ, Gavarret J, Bianchi FC, Pumphrey NJ, Ladell K, Gostick E, Sewell AK, Lissin NM, Harwood NE, Molloy PE, Li Y, Cameron BJ, Sami M, Baston EE, Todorov PT, Paston SJ, Dennis RE, Harper JV, Dunn SM, Ashfield R, Johnson A, McGrath Y, Plesa G, June CH, Kalos M, Price DA, Vuidepot A, Williams DD, Sutton DH, Jakobsen BK. Monoclonal TCR-redirected tumor cell killing. Nat Med. 2012 Jun; 18(6):980-7.
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Soghoian DZ, Jessen H, Flanders M, Sierra-Davidson K, Cutler S, Pertel T, Ranasinghe S, Lindqvist M, Davis I, Lane K, Rychert J, Rosenberg ES, Piechocka-Trocha A, Brass AL, Brenchley JM, Walker BD, Streeck H. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci Transl Med. 2012 Feb 29; 4(123):123ra25.
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Moysey RK, Li Y, Paston SJ, Baston EE, Sami MS, Cameron BJ, Gavarret J, Todorov P, Vuidepot A, Dunn SM, Pumphrey NJ, Adams KJ, Yuan F, Dennis RE, Sutton DH, Johnson AD, Brewer JE, Ashfield R, Lissin NM, Jakobsen BK. High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation. Protein Cell. 2010 Dec; 1(12):1118-27.
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Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J Immunol. 2011 Feb 1; 186(3):1627-37.
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Yeh N, Glosson NL, Wang N, Guindon L, McKinley C, Hamada H, Li Q, Dutton RW, Shrikant P, Zhou B, Brutkiewicz RR, Blum JS, Kaplan MH. Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol. 2010 Aug 15; 185(4):2089-98.
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