"Thapsigargin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
| Descriptor ID |
D019284
|
| MeSH Number(s) |
D02.455.426.392.368.284.500.888 D02.455.849.765.793.888
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thapsigargin".
Below are MeSH descriptors whose meaning is more specific than "Thapsigargin".
This graph shows the total number of publications written about "Thapsigargin" by people in this website by year, and whether "Thapsigargin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thapsigargin" by people in Profiles.
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Potier M, Gonzalez JC, Motiani RK, Abdullaev IF, Bisaillon JM, Singer HA, Trebak M. Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration. FASEB J. 2009 Aug; 23(8):2425-37.
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Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M. Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation. Circ Res. 2008 Nov 21; 103(11):1289-99.
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Pino SC, O'Sullivan-Murphy B, Lidstone EA, Thornley TB, Jurczyk A, Urano F, Greiner DL, Mordes JP, Rossini AA, Bortell R. Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response. Cell Stress Chaperones. 2008 Dec; 13(4):421-34.
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Zhang YA, Tuft RA, Lifshitz LM, Fogarty KE, Singer JJ, Zou H. Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2448-61.
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Carraway RE, Mitra SP. Neurotensin enhances agonist-induced cAMP accumulation in PC3 cells via Ca2+ -dependent adenylyl cyclase(s). Mol Cell Endocrinol. 1998 Sep 25; 144(1-2):47-57.
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ZhuGe R, Li S, Chen TH, Hsu WH. Alpha2-adrenergic receptor-mediated Ca2+ influx and release in porcine myometrial cells. Biol Reprod. 1997 May; 56(5):1343-50.
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Zhuge R, Hsu WH. The caffeine- and ryanodine-sensitive Ca++ store in porcine myometrial cells: its heterogeneity of all-or-none Ca++ release. J Pharmacol Exp Ther. 1995 Dec; 275(3):1077-83.
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Hansen M, Boitano S, Dirksen ER, Sanderson MJ. A role for phospholipase C activity but not ryanodine receptors in the initiation and propagation of intercellular calcium waves. J Cell Sci. 1995 Jul; 108 ( Pt 7):2583-90.
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Boitano S, Sanderson MJ, Dirksen ER. A role for Ca(2+)-conducting ion channels in mechanically-induced signal transduction of airway epithelial cells. J Cell Sci. 1994 Nov; 107 ( Pt 11):3037-44.
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Charles AC, Dirksen ER, Merrill JE, Sanderson MJ. Mechanisms of intercellular calcium signaling in glial cells studied with dantrolene and thapsigargin. Glia. 1993 Feb; 7(2):134-45.