"Thapsigargin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
Descriptor ID |
D019284
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MeSH Number(s) |
D02.455.426.392.368.284.500.888 D02.455.849.765.793.888
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thapsigargin".
Below are MeSH descriptors whose meaning is more specific than "Thapsigargin".
This graph shows the total number of publications written about "Thapsigargin" by people in this website by year, and whether "Thapsigargin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 |
1997 | 0 | 3 | 3 |
2003 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2007 | 0 | 1 | 1 |
2008 | 0 | 3 | 3 |
2010 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Thapsigargin" by people in Profiles.
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Zhang N, Fissore RA. Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs. J Cell Physiol. 2014 Nov; 229(11):1842-54.
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Liu X, Ong HL, Pani B, Johnson K, Swaim WB, Singh B, Ambudkar I. Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE. Cell Calcium. 2010 Jun; 47(6):491-9.
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Potier M, Gonzalez JC, Motiani RK, Abdullaev IF, Bisaillon JM, Singer HA, Trebak M. Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration. FASEB J. 2009 Aug; 23(8):2425-37.
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Krapf D, O'Brien ED, Cabada MO, Visconti PE, Arranz SE. Egg water from the amphibian Bufo arenarum modulates the ability of homologous sperm to undergo the acrosome reaction in the presence of the vitelline envelope. Biol Reprod. 2009 Feb; 80(2):311-9.
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Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M. Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation. Circ Res. 2008 Nov 21; 103(11):1289-99.
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Pino SC, O'Sullivan-Murphy B, Lidstone EA, Thornley TB, Jurczyk A, Urano F, Greiner DL, Mordes JP, Rossini AA, Bortell R. Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response. Cell Stress Chaperones. 2008 Dec; 13(4):421-34.
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Verbert L, Lee B, Kocks SL, Assefa Z, Parys JB, Missiaen L, Callewaert G, Fissore RA, De Smedt H, Bultynck G. Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling. Biol Cell. 2008 Jan; 100(1):39-49.
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Zhang YA, Tuft RA, Lifshitz LM, Fogarty KE, Singer JJ, Zou H. Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2448-61.
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Benimetskaya L, Lai JC, Khvorova A, Wu S, Hua E, Miller P, Zhang LM, Stein CA. Relative Bcl-2 independence of drug-induced cytotoxicity and resistance in 518A2 melanoma cells. Clin Cancer Res. 2004 Dec 15; 10(24):8371-9.
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Tjiattas L, Ortiz DO, Dhivant S, Mitton K, Rogers E, Shea TB. Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation. Aging Cell. 2004 Apr; 3(2):71-6.