Uric Acid

"Uric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.

Descriptor ID	D014527
MeSH Number(s)	D03.132.960.877 D03.633.100.759.758.824.877
Concept/Terms	Uric Acid Uric Acid Acid, Uric 2,6,8-Trihydroxypurine Trioxopurine Potassium Urate Potassium Urate Urate, Potassium Urate Urate Ammonium Acid Urate Ammonium Acid Urate Acid Urate, Ammonium Urate, Ammonium Acid Sodium Urate Monohydrate Sodium Urate Monohydrate Monohydrate, Sodium Urate Urate Monohydrate, Sodium Monosodium Urate Monohydrate Monohydrate, Monosodium Urate Urate Monohydrate, Monosodium Sodium Acid Urate Monohydrate Sodium Urate Urate, Sodium Monosodium Urate Urate, Monosodium Sodium Acid Urate Acid Urate, Sodium Urate, Sodium Acid

Below are MeSH descriptors whose meaning is more general than "Uric Acid".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Alkaloids [D03.132]
Xanthines [D03.132.960]
Uric Acid [D03.132.960.877]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purinones [D03.633.100.759.758]
Xanthines [D03.633.100.759.758.824]
Uric Acid [D03.633.100.759.758.824.877]

Below are MeSH descriptors whose meaning is related to "Uric Acid".

Below are MeSH descriptors whose meaning is more specific than "Uric Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Uric Acid" by people in this website by year, and whether "Uric Acid" was a major or minor topic of these publications.

Bar chart showing 1 publications over 1 distinct years, with a maximum of 1 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	1	0	1

Below are the most recent publications written about "Uric Acid" by people in Profiles.

Kiltz U, Smolen J, Bardin T, Cohen Solal A, Dalbeth N, Doherty M, Engel B, Flader C, Kay J, Matsuoka M, Perez-Ruiz F, da Rocha Castelar-Pinheiro G, Saag K, So A, Vazquez Mellado J, Weisman M, Westhoff TH, Yamanaka H, Braun J. Treat-to-target (T2T) recommendations for gout. Ann Rheum Dis. 2017 04; 76(4):632-638.

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Angelopoulos TJ, Lowndes J, Sinnett S, Rippe JM. Fructose containing sugars do not raise blood pressure or uric acid at normal levels of human consumption. J Clin Hypertens (Greenwich). 2015 Feb; 17(2):87-94.

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Baraf HS, Yood RA, Ottery FD, Sundy JS, Becker MA. Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy. J Clin Rheumatol. 2014 Dec; 20(8):427-32.

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Reber LL, Marichal T, Sokolove J, Starkl P, Gaudenzio N, Iwakura Y, Karasuyama H, Schwartz LB, Robinson WH, Tsai M, Galli SJ. Contribution of mast cell-derived interleukin-1? to uric acid crystal-induced acute arthritis in mice. Arthritis Rheumatol. 2014 Oct; 66(10):2881-91.

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Yood RA, Ottery FD, Irish W, Wolfson M. Effect of pegloticase on renal function in patients with chronic kidney disease: a post hoc subgroup analysis of 2 randomized, placebo-controlled, phase 3 clinical trials. BMC Res Notes. 2014 Jan 21; 7:54.

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Baraf HS, Becker MA, Gutierrez-Urena SR, Treadwell EL, Vazquez-Mellado J, Rehrig CD, Ottery FD, Sundy JS, Yood RA. Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy. Arthritis Res Ther. 2013 Sep 26; 15(5):R137.

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Yu Z, Lowndes J, Rippe J. High-fructose corn syrup and sucrose have equivalent effects on energy-regulating hormones at normal human consumption levels. Nutr Res. 2013 Dec; 33(12):1043-52.

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Harrold LR, Mazor KM, Negron A, Ogarek J, Firneno C, Yood RA. Primary care providers' knowledge, beliefs and treatment practices for gout: results of a physician questionnaire. Rheumatology (Oxford). 2013 Sep; 52(9):1623-9.

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Becker MA, Baraf HS, Yood RA, Dillon A, V?zquez-Mellado J, Ottery FD, Khanna D, Sundy JS. Long-term safety of pegloticase in chronic gout refractory to conventional treatment. Ann Rheum Dis. 2013 Sep 01; 72(9):1469-74.

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Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, Treadwell EL, V?zquez-Mellado J, White WB, Lipsky PE, Horowitz Z, Huang W, Maroli AN, Waltrip RW, Hamburger SA, Becker MA. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials. JAMA. 2011 Aug 17; 306(7):711-20.

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