 Uric Acid
"Uric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
| Descriptor ID |
D014527
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| MeSH Number(s) |
D03.132.960.877 D03.438.759.758.824.877
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| Concept/Terms |
Uric Acid- Uric Acid
- Acid, Uric
- Trioxopurine
- 2,6,8-Trihydroxypurine
Sodium Urate Monohydrate- Sodium Urate Monohydrate
- Monohydrate, Sodium Urate
- Urate Monohydrate, Sodium
- Monosodium Urate Monohydrate
- Monohydrate, Monosodium Urate
- Urate Monohydrate, Monosodium
- Sodium Acid Urate Monohydrate
- Sodium Urate
- Urate, Sodium
- Monosodium Urate
- Urate, Monosodium
- Sodium Acid Urate
- Acid Urate, Sodium
- Urate, Sodium Acid
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Below are MeSH descriptors whose meaning is more general than "Uric Acid".
Below are MeSH descriptors whose meaning is more specific than "Uric Acid".
This graph shows the total number of publications written about "Uric Acid" by people in this website by year, and whether "Uric Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 1 | 2 | 3 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 3 | 3 | | 2014 | 1 | 2 | 3 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Uric Acid" by people in Profiles.
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Rajan S, Zalpuri I, Harrington A, Cimpeanu C, Song X, Fan X. Relationship between serum uric acid level and cardiometabolic risks in nondiabetic patients with schizophrenia. Int Clin Psychopharmacol. 2016 Jan; 31(1):51-6.
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Iracheta-Vellve A, Petrasek J, Satishchandran A, Gyongyosi B, Saha B, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. J Hepatol. 2015 Nov; 63(5):1147-55.
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Petrasek J, Iracheta-Vellve A, Saha B, Satishchandran A, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease. J Leukoc Biol. 2015 Aug; 98(2):249-56.
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Juraschek SP, Kovell LC, Miller ER, Gelber AC. Gout, urate-lowering therapy, and uric acid levels among adults in the United States. Arthritis Care Res (Hoboken). 2015 Apr; 67(4):588-92.
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Baraf HS, Yood RA, Ottery FD, Sundy JS, Becker MA. Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy. J Clin Rheumatol. 2014 Dec; 20(8):427-32.
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Kataoka H, Yang K, Rock KL. The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung. Eur J Pharmacol. 2015 Jan 5; 746:174-9.
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Reber LL, Marichal T, Sokolove J, Starkl P, Gaudenzio N, Iwakura Y, Karasuyama H, Schwartz LB, Robinson WH, Tsai M, Galli SJ. Contribution of mast cell-derived interleukin-1ß to uric acid crystal-induced acute arthritis in mice. Arthritis Rheumatol. 2014 Oct; 66(10):2881-91.
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Yood RA, Ottery FD, Irish W, Wolfson M. Effect of pegloticase on renal function in patients with chronic kidney disease: a post hoc subgroup analysis of 2 randomized, placebo-controlled, phase 3 clinical trials. BMC Res Notes. 2014 Jan 21; 7:54.
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Baraf HS, Becker MA, Gutierrez-Urena SR, Treadwell EL, Vazquez-Mellado J, Rehrig CD, Ottery FD, Sundy JS, Yood RA. Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy. Arthritis Res Ther. 2013 Sep 26; 15(5):R137.
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Harrold LR, Mazor KM, Negron A, Ogarek J, Firneno C, Yood RA. Primary care providers' knowledge, beliefs and treatment practices for gout: results of a physician questionnaire. Rheumatology (Oxford). 2013 Sep; 52(9):1623-9.
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