Murine Acquired Immunodeficiency Syndrome
"Murine Acquired Immunodeficiency Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acquired defect of cellular immunity that occurs in mice infected with mouse leukemia viruses (MuLV). The syndrome shows striking similarities with human AIDS and is characterized by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas.
Descriptor ID |
D016183
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MeSH Number(s) |
C02.782.815.650 C02.928.650 C22.795.650
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Concept/Terms |
Murine Acquired Immunodeficiency Syndrome- Murine Acquired Immunodeficiency Syndrome
- Murine Acquired Immuno-Deficiency Syndrome
- Murine Acquired Immuno Deficiency Syndrome
- MAIDS
- Murine Acquired Immune Deficiency Syndrome
- AIDS, Murine
- AIDSs, Murine
- Murine AIDSs
- Murine AIDS
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Below are MeSH descriptors whose meaning is more general than "Murine Acquired Immunodeficiency Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Murine Acquired Immunodeficiency Syndrome".
This graph shows the total number of publications written about "Murine Acquired Immunodeficiency Syndrome" by people in this website by year, and whether "Murine Acquired Immunodeficiency Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 0 | 1 | 1 |
1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Murine Acquired Immunodeficiency Syndrome" by people in Profiles.
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Yen MH, Lepak N, Swain SL. Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis. J Immunol. 2002 Jul 15; 169(2):722-31.
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Harris DP, Koch S, Mullen LM, Swain SL. B cell immunodeficiency fails to develop in CD4-deficient mice infected with BM5: murine AIDS as a multistep disease. J Immunol. 2001 May 15; 166(10):6041-9.
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Andrews C, Swain SL, Muralidhar G. CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells. J Immunol. 1997 Sep 01; 159(5):2132-8.
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Muralidhar G, Koch S, Broome HE, Swain SL. TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation. J Immunol. 1996 Jul 15; 157(2):625-35.
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Ishigatsubo Y, Steinberg AD, Krieg A, Klinman DM. Increased utilization of polyreactive B cells during periods of generalized immune activation. Autoimmunity. 1995; 22(2):113-9.
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Koch S, Muralidhar G, Swain SL. Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease. J Immunol. 1994 Jun 01; 152(11):5548-56.
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Muralidhar G, Koch S, Haas M, Swain SL. CD4 T cells in murine acquired immunodeficiency syndrome: polyclonal progression to anergy. J Exp Med. 1992 Jun 01; 175(6):1589-99.
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Klinman DM, Krieg A, Conover J, Ussery MA, Black PL. Effect of cyclophosphamide, total body irradiation, and zidovudine on retrovirus proliferation and disease progression in murine AIDS. AIDS Res Hum Retroviruses. 1992 Jan; 8(1):101-6.