 Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
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| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.425.747 G12.450.050.400.545
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| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blastogenesis
- Lymphoblast Transformation
- Transformation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Blast
- Transformation, Lymphoblast
- Blast Transformation
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1981 | 1 | 3 | 4 | | 1982 | 2 | 9 | 11 | | 1983 | 5 | 8 | 13 | | 1984 | 7 | 5 | 12 | | 1985 | 1 | 7 | 8 | | 1986 | 3 | 6 | 9 | | 1987 | 3 | 8 | 11 | | 1988 | 6 | 3 | 9 | | 1989 | 7 | 5 | 12 | | 1990 | 0 | 7 | 7 | | 1991 | 5 | 9 | 14 | | 1992 | 0 | 10 | 10 | | 1993 | 6 | 4 | 10 | | 1994 | 4 | 10 | 14 | | 1995 | 5 | 9 | 14 | | 1996 | 10 | 12 | 22 | | 1997 | 4 | 4 | 8 | | 1998 | 5 | 13 | 18 | | 1999 | 7 | 14 | 21 | | 2000 | 8 | 15 | 23 | | 2001 | 4 | 17 | 21 | | 2002 | 10 | 17 | 27 | | 2003 | 7 | 9 | 16 | | 2004 | 7 | 9 | 16 | | 2005 | 8 | 22 | 30 | | 2006 | 10 | 12 | 22 | | 2007 | 6 | 18 | 24 | | 2008 | 7 | 14 | 21 | | 2009 | 5 | 10 | 15 | | 2010 | 6 | 11 | 17 | | 2011 | 7 | 4 | 11 | | 2012 | 4 | 13 | 17 | | 2013 | 3 | 9 | 12 | | 2014 | 4 | 8 | 12 | | 2015 | 3 | 6 | 9 | | 2016 | 3 | 1 | 4 | | 2017 | 0 | 4 | 4 | | 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Mansouri S, Patel S, Katikaneni DS, Blaauboer SM, Wang W, Schattgen S, Fitzgerald K, Jin L. Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo. Mucosal Immunol. 2019 01; 12(1):277-289.
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Hatfield SD, Daniels KA, O'Donnell CL, Waggoner SN, Welsh RM. Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity. Virology. 2018 06; 519:131-144.
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Carpenter SM, Yang JD, Lee J, Barreira-Silva P, Behar SM. Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis. PLoS Pathog. 2017 Nov; 13(11):e1006704.
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Shin HM, Kapoor VN, Kim G, Li P, Kim HR, Suresh M, Kaech SM, Wherry EJ, Selin LK, Leonard WJ, Welsh RM, Berg LJ. Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. PLoS Pathog. 2017 Aug; 13(8):e1006544.
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Figueiredo MM, Costa PAC, Diniz SQ, Henriques PM, Kano FS, Tada MS, Pereira DB, Soares IS, Martins-Filho OA, Jankovic D, Gazzinelli RT, Antonelli LRDV. T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection. PLoS Pathog. 2017 Jul; 13(7):e1006484.
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Aubert G, Strauss KA, Lansdorp PM, Rider NL. Defects in lymphocyte telomere homeostasis contribute to cellular immune phenotype in patients with cartilage-hair hypoplasia. J Allergy Clin Immunol. 2017 Oct; 140(4):1120-1129.e1.
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Reboldi A, Arnon TI, Rodda LB, Atakilit A, Sheppard D, Cyster JG. IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches. Science. 2016 May 13; 352(6287):aaf4822.
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Serr I, Fürst RW, Achenbach P, Scherm MG, Gökmen F, Haupt F, Sedlmeier EM, Knopff A, Shultz L, Willis RA, Ziegler AG, Daniel C. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016 Mar 15; 7:10991.
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Booty MG, Nunes-Alves C, Carpenter SM, Jayaraman P, Behar SM. Multiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during Tuberculosis. J Immunol. 2016 Feb 15; 196(4):1822-31.
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Carpenter SM, Nunes-Alves C, Booty MG, Way SS, Behar SM. A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis. PLoS Pathog. 2016 Jan; 12(1):e1005380.
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