Antibodies, Blocking

"Antibodies, Blocking" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)

Descriptor ID	D019138
MeSH Number(s)	D12.776.124.486.485.114.143 D12.776.124.790.651.114.143 D12.776.377.715.548.114.143
Concept/Terms	Antibodies, Blocking Antibodies, Blocking Blocking Antibodies Enhancing Antibodies Enhancing Antibodies Antibodies, Enhancing

Below are MeSH descriptors whose meaning is more general than "Antibodies, Blocking".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Antibodies [D12.776.124.486.485.114]
Antibodies, Blocking [D12.776.124.486.485.114.143]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Antibodies [D12.776.124.790.651.114]
Antibodies, Blocking [D12.776.124.790.651.114.143]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]
Antibodies [D12.776.377.715.548.114]
Antibodies, Blocking [D12.776.377.715.548.114.143]

Below are MeSH descriptors whose meaning is more specific than "Antibodies, Blocking".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antibodies, Blocking" by people in this website by year, and whether "Antibodies, Blocking" was a major or minor topic of these publications.

Bar chart showing 29 publications over 18 distinct years, with a maximum of 5 publications in 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
1999	1	4	5
2000	0	2	2
2001	2	1	3
2002	0	2	2
2003	1	1	2
2004	0	1	1
2005	0	2	2
2008	0	1	1
2010	0	1	1
2011	0	1	1
2012	1	1	2
2013	0	1	1
2017	0	1	1
2018	1	0	1
2019	0	1	1
2021	0	1	1

Below are the most recent publications written about "Antibodies, Blocking" by people in Profiles.

Katzelnick LC, Zambrana JV, Elizondo D, Collado D, Garcia N, Arguello S, Mercado JC, Miranda T, Ampie O, Mercado BL, Narvaez C, Gresh L, Binder RA, Ojeda S, Sanchez N, Plazaola M, Latta K, Schiller A, Coloma J, Carrillo FB, Narvaez F, Halloran ME, Gordon A, Kuan G, Balmaseda A, Harris E. Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term. Sci Transl Med. 2021 Oct 06; 13(614):eabg9478.

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Esteve P, Rueda-Carrasco J, In?s Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandon?s ?, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, R?bano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Dom?nguez M, Bovolenta P. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nat Neurosci. 2019 08; 22(8):1258-1268.

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Richmond JM, Strassner JP, Zapata L, Garg M, Riding RL, Refat MA, Fan X, Azzolino V, Tovar-Garza A, Tsurushita N, Pandya AG, Tso JY, Harris JE. Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo. Sci Transl Med. 2018 07 18; 10(450).

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Roubert A, Gregory K, Li Y, Pfalzer AC, Li J, Schneider SS, Wood RJ, Liu Z. The influence of tumor necrosis factor-a on the tumorigenic Wnt-signaling pathway in human mammary tissue from obese women. Oncotarget. 2017 May 30; 8(22):36127-36136.

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Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR. The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science. 2016 Feb 26; 351(6276):933-9.

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Clapham H, Cummings DA, Nisalak A, Kalayanarooj S, Thaisomboonsuk B, Klungthong C, Fernandez S, Srikiatkhachorn A, Macareo LR, Lessler J, Reiser J, Yoon IK. Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004262.

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Riella LV, Yang J, Chock S, Safa K, Magee CN, Vanguri V, Elyaman W, Lahoud Y, Yagita H, Abdi R, Najafian N, Medina-Pestana JO, Chandraker A. Jagged2-signaling promotes IL-6-dependent transplant rejection. Eur J Immunol. 2013 Jun; 43(6):1449-58.

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Sada-Ovalle I, Ch?vez-Gal?n L, Torre-Bouscoulet L, Nava-Gami?o L, Barrera L, Jayaraman P, Torres-Rojas M, Salazar-Lezama MA, Behar SM. The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis. J Immunol. 2012 Dec 15; 189(12):5896-902.

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Miska J, Bas E, Devarajan P, Chen Z. Autoimmunity-mediated antitumor immunity: tumor as an immunoprivileged self. Eur J Immunol. 2012 Oct; 42(10):2584-96.

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Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM. Relative contributions of dectin-1 and complement to immune responses to particulate ?-glucans. J Immunol. 2012 Jul 01; 189(1):312-7.

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