"Levamisole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
| Descriptor ID |
D007978
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| MeSH Number(s) |
D02.886.675.346 D03.383.129.308.480 D03.383.129.708.346
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Levamisole".
Below are MeSH descriptors whose meaning is more specific than "Levamisole".
This graph shows the total number of publications written about "Levamisole" by people in this website by year, and whether "Levamisole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Levamisole" by people in Profiles.
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Williams PDE, Brewer MT, Aroian RV, Robertson AP, Martin RJ. The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole. PLoS Pathog. 2024 May; 20(5):e1011835.
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Fredericks C, Yon JR, Alex G, Morton M, Messer T, Bokhari F, Poulakidas S. Levamisole-induced Necrosis Syndrome: Presentation and Management. Wounds. 2017 Mar; 29(3):71-76.
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Lee KC, Ladizinski B, Nutan FN. Systemic complications of levamisole toxicity. J Am Acad Dermatol. 2012 Oct; 67(4):791-2.
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Chai PR, Bastan W, Machan J, Hack JB, Babu KM. Levamisole exposure and hematologic indices in cocaine users. Acad Emerg Med. 2011 Nov; 18(11):1141-7.
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Hu Y, Platzer EG, Bellier A, Aroian RV. Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):5955-60.
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Francis MM, Evans SP, Jensen M, Madsen DM, Mancuso J, Norman KR, Maricq AV. The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction. Neuron. 2005 May 19; 46(4):581-94.
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Hesketh PJ, Bulger KN. Role of adjuvant therapy in colorectal cancer. Adv Intern Med. 1991; 36:219-47.