"G(M3) Ganglioside" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
| Descriptor ID |
D005679
|
| MeSH Number(s) |
D09.400.410.420.025.475.510 D10.390.470.025.475.510 D10.570.877.360.025.475.510
|
| Concept/Terms |
G(M3) Ganglioside- G(M3) Ganglioside
- Sialyl Lactosylceramide
- Lactosylceramide, Sialyl
- Ganglioside GM3
- GM3, Ganglioside
- Hematoside
- Sialyllactosylceramide
- II3NeuAcLacCer
|
Below are MeSH descriptors whose meaning is more general than "G(M3) Ganglioside".
Below are MeSH descriptors whose meaning is more specific than "G(M3) Ganglioside".
This graph shows the total number of publications written about "G(M3) Ganglioside" by people in this website by year, and whether "G(M3) Ganglioside" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "G(M3) Ganglioside" by people in Profiles.
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Dookwah M, Wagner SK, Ishihara M, Yu SH, Ulrichs H, Kulik MJ, Zeltner N, Dalton S, Strauss KA, Aoki K, Steet R, Tiemeyer M. Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants. Hum Mol Genet. 2023 Dec 01; 32(24):3323-3341.
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Yoshikawa M, Go S, Suzuki S, Suzuki A, Katori Y, Morlet T, Gottlieb SM, Fujiwara M, Iwasaki K, Strauss KA, Inokuchi J. Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells. Hum Mol Genet. 2015 May 15; 24(10):2796-807.
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Miranda PV, Allaire A, Sosnik J, Visconti PE. Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol Reprod. 2009 May; 80(5):897-904.