"Isoprostanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.
| Descriptor ID |
D028421
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| MeSH Number(s) |
D10.251.355.255.100.375 D10.251.355.310.166.775 D10.251.355.411
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Isoprostanes".
Below are MeSH descriptors whose meaning is more specific than "Isoprostanes".
This graph shows the total number of publications written about "Isoprostanes" by people in this website by year, and whether "Isoprostanes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Isoprostanes" by people in Profiles.
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Wu H, Olmsted A, Cantonwine DE, Shahsavari S, Rahil T, Sites C, Pilsner JR. Urinary phthalate and phthalate alternative metabolites and isoprostane among couples undergoing fertility treatment. Environ Res. 2017 Feb; 153:1-7.
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Fontes JD, Yamamoto JF, Larson MG, Wang N, Dallmeier D, Rienstra M, Schnabel RB, Vasan RS, Keaney JF, Benjamin EJ. Clinical correlates of change in inflammatory biomarkers: The?Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):217-23.
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Sowers M, McConnell D, Jannausch ML, Randolph JF, Brook R, Gold EB, Crawford S, Lasley B. Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress. Clin Endocrinol (Oxf). 2008 May; 68(5):806-13.
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Tomey KM, Sowers MR, Li X, McConnell DS, Crawford S, Gold EB, Lasley B, Randolph JF. Dietary fat subgroups, zinc, and vegetable components are related to urine F2a-isoprostane concentration, a measure of oxidative stress, in midlife women. J Nutr. 2007 Nov; 137(11):2412-9.