Parkinson Disease

"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Descriptor ID	D010300
MeSH Number(s)	C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
Concept/Terms	Parkinson Disease Parkinson Disease Idiopathic Parkinson's Disease Lewy Body Parkinson Disease Lewy Body Parkinson's Disease Primary Parkinsonism Parkinsonism, Primary Parkinson Disease, Idiopathic Parkinson's Disease Parkinson's Disease, Idiopathic Parkinson's Disease, Lewy Body Idiopathic Parkinson Disease Paralysis Agitans

Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Basal Ganglia Diseases [C10.228.140.079]
Parkinsonian Disorders [C10.228.140.079.862]
Parkinson Disease [C10.228.140.079.862.500]
Movement Disorders [C10.228.662]
Parkinsonian Disorders [C10.228.662.600]
Parkinson Disease [C10.228.662.600.400]
Neurodegenerative Diseases [C10.574]
Parkinson Disease [C10.574.812]

Below are MeSH descriptors whose meaning is related to "Parkinson Disease".

Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.

Bar chart showing 125 publications over 26 distinct years, with a maximum of 15 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	2	0	2
2000	2	0	2
2001	2	0	2
2002	1	2	3
2003	0	1	1
2004	2	1	3
2005	1	1	2
2006	5	0	5
2007	2	1	3
2008	3	1	4
2010	4	0	4
2011	1	3	4
2012	2	5	7
2014	1	0	1
2015	2	1	3
2016	1	0	1
2017	7	2	9
2018	6	2	8
2019	10	3	13
2020	12	3	15
2021	5	1	6
2022	7	1	8
2023	6	0	6
2024	7	2	9
2025	3	0	3

Below are the most recent publications written about "Parkinson Disease" by people in Profiles.

Vetkas A, Yang A, Boutet A, Cheyuo C, Santyr B, Sarica C, Davidson B, Fomenko A, Samuel N, Lang S, Sumarac S, Milosevic L, Valiante T, Hodaie M, Kalia SK, Lozano AM. One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders. Mov Disord Clin Pract. 2025 Dec; 12(12):2080-2091.

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Sperling SA, Dong J, Lapin B, Li Y. Reliability and validity of in-home tele-neuropsychological testing in patients with Parkinson's disease: A randomized trial. Clin Neuropsychol. 2025 Jul; 39(5):1119-1154.

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Anis S, Chaparro-Solano HM, Peixoto Leal T, Sperling SA, Sonneborn C, Callegari Piccinin C, Inca-Martinez M, Cornejo-Olivas M, Illanes-Manrique M, Chana-Cuevas P, Safie Awad P, Jimena Hern?ndez-Medrano A, Cervantes-Arriaga A, F S Schuh A, R M Rieder C, Braga-Neto P, Andrei da Silva Sena A, Lopes Santos-Lobato B, M Gatto E, J Alvarado G, L Avila C, Tumas V, Foss MP, Borges V, Ballalai Ferraz H, Luis Orozco V?lez J, Mu?oz Ospina B, Moreno S, Pineda D, Esther Rios Pinto J, Olgu?n P, Cristobal Nu?ez J, Vi?uela A, O Espinal-Martinez A, Mori N, Mej?a-Rojas K, Medina-Colque A, Lucia Zuma Rosso A, Vila?a C, Ochoa-Valle E, Cornejo-Herrera I, Reyes-Perez P, L?zaro-Figueroa A, Let?cia de Moraes Alves A, Cury RG, Fernandez HH, Mata I. Differences and contributors to global cognitive performance in the underrepresented Latinx Parkinson's disease population. Clin Neuropsychol. 2025 10; 39(7):1905-1925.

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Xie F, Shen B, Luo Y, Zhou H, Xie Z, Zhu S, Wei X, Chang Z, Zhu Z, Ding C, Jin K, Yang C, Batzu L, Chaudhuri KR, Chan LL, Tan EK, Wang Q. Repetitive transcranial magnetic stimulation alleviates motor impairment in Parkinson's disease: association with peripheral inflammatory regulatory T-cells and SYT6. Mol Neurodegener. 2024 Oct 25; 19(1):80.

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Garc?a-Mar?n LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJC, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivi?res S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fern?ndez G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, H?berg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR, Jahanshad N, J?nsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lema?tre H, Li S, Liewald DCM, Lin H, Longstreth WT, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martinot JL, Mather KA, Mattay VS, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mirza-Schreiber N, Milaneschi Y, Mosley TH, M?hleisen TW, M?ller-Myhsok B, Maniega SM, Nauck M, Nho K, Niessen WJ, N?then MM, Nyquist PA, Oosterlaan J, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Psaty BM, P?tz B, Reppermund S, Rietschel MD, Risacher SL, Romanczuk-Seiferth N, Romero-Garcia R, Roshchupkin GV, Rotter JI, Sachdev PS, S?mann PG, Saremi A, Sargurupremraj M, Saykin AJ, Schmaal L, Schmidt H, Schmidt R, Schofield PR, Scholz M, Schumann G, Schwarz E, Shen L, Shin J, Sisodiya SM, Smith AV, Smoller JW, Soininen HS, Steen VM, Stein DJ, Stein JL, Thomopoulos SI, Toga AW, Tordesillas-Guti?rrez D, Trollor JN, Valdes-Hernandez MC, van T Ent D, van Bokhoven H, van der Meer D, van der Wee NJA, V?zquez-Bourgon J, Veltman DJ, Vernooij MW, Villringer A, Vinke LN, V?lzke H, Walter H, Wardlaw JM, Weinberger DR, Weiner MW, Wen W, Westlye LT, Westman E, White T, Witte AV, Wolf C, Yang J, Zwiers MP, Ikram MA, Seshadri S, Thompson PM, Satizabal CL, Medland SE, Renter?a ME. Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. Nat Genet. 2024 Nov; 56(11):2333-2344.

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Ahn JH, Kim BS, Han KD, Choi HL, Jung W, Cho JW, Youn J, Shin DW. Risk of Parkinson's disease in spinal cord injury: a nationwide cohort study in South Korea. Sci Rep. 2024 10 03; 14(1):23016.

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DeSilva GS, Upadhyay P, Manxhari M, Gopal D, Smith KM. Variability in Vowel Space in Parkinson's Disease: Associations With Cognitive and Motor Impairment. J Speech Lang Hear Res. 2024 Oct 08; 67(10):3566-3578.

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Cheyuo C, Germann J, Yamamoto K, Zibly Z, Krishna V, Sarica C, Borges YFF, Vetkas A, Kalia SK, Hodaie M, Fasano A, Schwartz ML, Elias WJ, Lozano AM. Probabilistic Refinement of Focused Ultrasound Thalamotomy Targeting for Parkinson's Disease Tremor. Mov Disord. 2024 Nov; 39(11):2004-2013.

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Hop PJ, Lai D, Keagle PJ, Baron DM, Kenna BJ, Kooyman M, Halter C, Straniero L, Asselta R, Bonvegna S, Soto-Beasley AI, Wszolek ZK, Uitti RJ, Isaias IU, Pezzoli G, Ticozzi N, Ross OA, Veldink JH, Foroud TM, Kenna KP, Landers JE. Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson's disease. Nat Genet. 2024 Jul; 56(7):1371-1376.

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Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VGH, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman R. Skin Biopsy Detection of Phosphorylated a-Synuclein in Patients With Synucleinopathies. JAMA. 2024 04 16; 331(15):1298-1306.

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