"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
|
| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
|
| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
|
Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Chudzik A, Sledzianowski A, Przybyszewski AW. Machine Learning and Digital Biomarkers Can Detect Early Stages of Neurodegenerative Diseases. Sensors (Basel). 2024 Feb 29; 24(5).
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Przybyszewski AW, Sledzianowski A, Chudzik A, Szlufik S, Koziorowski D. Machine Learning and Eye Movements Give Insights into Neurodegenerative Disease Mechanisms. Sensors (Basel). 2023 Feb 14; 23(4).
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Ajoolabady A, Aslkhodapasandhokmabad H, Henninger N, Demillard LJ, Nikanfar M, Nourazarian A, Ren J. Targeting autophagy in neurodegenerative diseases: From molecular mechanisms to clinical therapeutics. Clin Exp Pharmacol Physiol. 2021 Jul; 48(7):943-953.
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Ye C, Li J, Hao S, Liu M, Jin H, Zheng L, Xia M, Jin B, Zhu C, Alfreds ST, Stearns F, Kanov L, Sylvester KG, Widen E, McElhinney D, Ling XB. Identification of elders at higher risk for fall with statewide electronic health records and a machine learning algorithm. Int J Med Inform. 2020 05; 137:104105.
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Szlufik S, Duszynska-Lysak K, Przybyszewski A, Laskowska-Levy I, Drzewinska A, Dutkiewicz J, Mandat T, Habela P, Koziorowski D. The potential neuromodulatory impact of subthalamic nucleus deep brain stimulation on Parkinson's disease progression. J Clin Neurosci. 2020 Mar; 73:150-154.
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Szlufik S, Przybyszewski A, Dutkiewicz J, Mandat T, Habela P, Koziorowski D. Evaluating reflexive saccades and UDPRS as markers of Deep Brain Stimulation and Best Medical Treatment improvements in Parkinson's disease patients: a prospective controlled study. Neurol Neurochir Pol. 2019; 53(5):341-347.
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Lodato MA, Walsh CA. Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms. Hum Mol Genet. 2019 10 15; 28(R2):R197-R206.
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Novak P, Pimentel Maldonado DA, Novak V. Safety and preliminary efficacy of intranasal insulin for cognitive impairment in Parkinson disease and multiple system atrophy: A double-blinded placebo-controlled pilot study. PLoS One. 2019; 14(4):e0214364.
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Ramirez-Zamora A, Pilitsis JG. In reply to: "Hyperhidrosis caused by deep brain stimulation in the posterior subthalamic area" by Patric Blomstedt MD, PhD. J Neurol Sci. 2017 09 15; 380:280.
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Eijkholt M, Cabrera LY, Ramirez-Zamora A, Pilitsis JG. Shaking Up the Debate: Ensuring the Ethical Use of DBS Intervention Criteria for Mid-Stage Parkinson's Patients. Neuromodulation. 2017 Jul; 20(5):411-416.