Purpura, Thrombocytopenic, Idiopathic

"Purpura, Thrombocytopenic, Idiopathic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.

Descriptor ID	D016553
MeSH Number(s)	C15.378.100.802.687.600 C15.378.140.855.925.750.600 C15.378.463.740 C20.111.759 C20.841.600 C23.550.414.950.687.600 C23.888.885.687.687.600
Concept/Terms	Purpura, Thrombocytopenic, Idiopathic Purpura, Thrombocytopenic, Idiopathic Idiopathic Thrombocytopenic Purpura Idiopathic Thrombocytopenic Purpuras Purpura, Idiopathic Thrombocytopenic Purpuras, Idiopathic Thrombocytopenic Thrombocytopenic Purpura, Idiopathic Thrombocytopenic Purpuras, Idiopathic Immune Thrombocytopenic Purpura Immune Thrombocytopenic Purpuras Purpura, Immune Thrombocytopenic Purpuras, Immune Thrombocytopenic Thrombocytopenic Purpura, Immune Thrombocytopenic Purpuras, Immune Immune Thrombocytopenia Immune Thrombocytopenias Thrombocytopenia, Immune Thrombocytopenias, Immune Thrombocytopenic Purpura, Autoimmune Werlhof Disease Disease, Werlhof Werlhof's Disease Disease, Werlhof's Werlhofs Disease Autoimmune Thrombocytopenia Autoimmune Thrombocytopenias Thrombocytopenia, Autoimmune Thrombocytopenias, Autoimmune Autoimmune Thrombocytopenic Purpura Autoimmune Thrombocytopenic Purpuras Purpura, Autoimmune Thrombocytopenic Purpuras, Autoimmune Thrombocytopenic Purpura, Thrombocytopenic, Autoimmune

Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombocytopenic, Idiopathic".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Blood Coagulation Disorders [C15.378.100]
Purpura [C15.378.100.802]
Purpura, Thrombocytopenic [C15.378.100.802.687]
Purpura, Thrombocytopenic, Idiopathic [C15.378.100.802.687.600]
Blood Platelet Disorders [C15.378.140]
Thrombocytopenia [C15.378.140.855]
Thrombotic Microangiopathies [C15.378.140.855.925]
Purpura, Thrombocytopenic [C15.378.140.855.925.750]
Purpura, Thrombocytopenic, Idiopathic [C15.378.140.855.925.750.600]
Hemorrhagic Disorders [C15.378.463]
Purpura, Thrombocytopenic, Idiopathic [C15.378.463.740]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Purpura, Thrombocytopenic, Idiopathic [C20.111.759]
Purpura, Thrombocytopenic [C20.841]
Purpura, Thrombocytopenic, Idiopathic [C20.841.600]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Hemorrhage [C23.550.414]
Purpura [C23.550.414.950]
Purpura, Thrombocytopenic [C23.550.414.950.687]
Purpura, Thrombocytopenic, Idiopathic [C23.550.414.950.687.600]
Signs and Symptoms [C23.888]
Skin Manifestations [C23.888.885]
Purpura [C23.888.885.687]
Purpura, Thrombocytopenic [C23.888.885.687.687]
Purpura, Thrombocytopenic, Idiopathic [C23.888.885.687.687.600]

Below are MeSH descriptors whose meaning is related to "Purpura, Thrombocytopenic, Idiopathic".

Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombocytopenic, Idiopathic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in this website by year, and whether "Purpura, Thrombocytopenic, Idiopathic" was a major or minor topic of these publications.

Bar chart showing 20 publications over 19 distinct years, with a maximum of 2 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	1	0	1
1996	1	0	1
1999	1	0	1
2002	1	0	1
2003	0	1	1
2004	2	0	2
2005	0	1	1
2007	0	1	1
2009	0	1	1
2011	1	0	1
2012	1	0	1
2013	1	0	1
2014	1	0	1
2015	1	0	1
2017	1	0	1
2018	1	0	1
2020	1	0	1
2021	1	0	1

Below are the most recent publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in Profiles.

Sandal R, Mishra K, Jandial A, Sahu KK, Siddiqui AD. Update on diagnosis and treatment of immune thrombocytopenia. Expert Rev Clin Pharmacol. 2021 May; 14(5):553-568.

View in: PubMed
Sahu KK, Siddiqui AD, Rezaei N, Cerny J. Challenges for management of immune thrombocytopenia during COVID-19 pandemic. J Med Virol. 2020 11; 92(11):2277-2282.

View in: PubMed
Goda V, Malik A, Kalmar T, Maroti Z, Patel B, Ujhazi B, Csomos K, Hale JE, Chen K, Bleesing J, Palma P, Cancrini C, Comeau AM, Krivan G, Walter JE. Partial RAG deficiency in a patient with?varicella infection, autoimmune cytopenia, and anticytokine antibodies. J Allergy Clin Immunol Pract. 2018 Sep - Oct; 6(5):1769-1771.e2.

View in: PubMed
Michelson AD. Immature platelet fraction in immune thrombocytopenia: Useful in diagnosis but does it predict bleeding? Pediatr Blood Cancer. 2018 02; 65(2).

View in: PubMed
Eyada TK, Amin DG, Samih I, Khedr SM. Human platelet antigen 1, 2 and 5 gene polymorphisms in Egyptians and their potential association with susceptibility to immune thrombocytopenic purpura in Egyptian patients. Hematology. 2018 Mar; 23(2):111-116.

View in: PubMed
Frelinger AL, Grace RF, Gerrits AJ, Berny-Lang MA, Brown T, Carmichael SL, Neufeld EJ, Michelson AD. Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP. Blood. 2015 Aug 13; 126(7):873-9.

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Navez J, Hubert C, Gigot JF, Navez B, Lambert C, Jamar F, Danse E, Lannoy V, Jabbour N. Does the site of platelet sequestration predict the response to splenectomy in adult patients with immune thrombocytopenic purpura? Platelets. 2015; 26(6):573-6.

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Psaila B, Bussel JB, Frelinger AL, Michelson AD. Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia: a reply to a rebuttal. J Thromb Haemost. 2013 May; 11(5):1002-3.

View in: PubMed
Michelson AD. Gray platelet syndrome. Blood. 2013 Jan 10; 121(2):250.

View in: PubMed
Psaila B, Bussel JB, Linden MD, Babula B, Li Y, Barnard MR, Tate C, Mathur K, Frelinger AL, Michelson AD. In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation. Blood. 2012 Apr 26; 119(17):4066-72.

View in: PubMed

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