"Inositol 1,4,5-Trisphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
- Inositol 1,4,5-Trisphosphate
- Inositol 1,4,5-Triphosphate
- Myoinositol 1,4,5-Triphosphate
- Myo-Inositol 1,4,5-Trisphosphate
Below are MeSH descriptors whose meaning is more general than "Inositol 1,4,5-Trisphosphate".
Below are MeSH descriptors whose meaning is more specific than "Inositol 1,4,5-Trisphosphate".
This graph shows the total number of publications written about "Inositol 1,4,5-Trisphosphate" by people in this website by year, and whether "Inositol 1,4,5-Trisphosphate" was a major or minor topic of these publications.
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Below are the most recent publications written about "Inositol 1,4,5-Trisphosphate" by people in Profiles.
Croisier H, Tan X, Chen J, Sneyd J, Sanderson MJ, Brook BS. Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015 Nov; 53(5):703-11.
Nelson C, Ambros V, Baehrecke EH. miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell. 2014 Nov 06; 56(3):376-388.
Tan X, Sanderson MJ. Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity. Br J Pharmacol. 2014 Feb; 171(3):646-62.
Fenton RA, Shea LG, Doddi C, Dobson JG. Myocardial adenosine A(1)-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1671-8.
Lee B, Yoon SY, Malcuit C, Parys JB, Fissore RA. Inositol 1,4,5-trisphosphate receptor 1 degradation in mouse eggs and impact on [Ca2+]i oscillations. J Cell Physiol. 2010 Jan; 222(1):238-47.
Ressmeyer AR, Bai Y, Delmotte P, Uy KF, Thistlethwaite P, Fraire A, Sato O, Ikebe M, Sanderson MJ. Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):179-91.
Bai Y, Edelmann M, Sanderson MJ. The contribution of inositol 1,4,5-trisphosphate and ryanodine receptors to agonist-induced Ca(2+) signaling of airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2009 Aug; 297(2):L347-61.
Lee B, Yoon SY, Fissore RA. Regulation of fertilization-initiated [Ca2+]i oscillations in mammalian eggs: a multi-pronged approach. Semin Cell Dev Biol. 2006 Apr; 17(2):274-84.
Sneyd J, Tsaneva-Atanasova K, Reznikov V, Bai Y, Sanderson MJ, Yule DI. A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1675-80.
Przyklenk K, Maynard M, Darling CE, Whittaker P. Pretreatment with D-myo-inositol trisphosphate reduces infarct size in rabbit hearts: role of inositol trisphosphate receptors and gap junctions in triggering protection. J Pharmacol Exp Ther. 2005 Sep; 314(3):1386-92.