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Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.

Kang S, Fernandes-Alnemri T, Rogers C, Mayes L, Wang Y, Dillon C, Roback L, Kaiser W, Oberst A, Sagara J, Fitzgerald KA, Green DR, Zhang J, Mocarski ES, Alnemri ES. Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nat Commun. 2015 Jun 24; 6:7515.

View in: PubMed