Receptor-Interacting Protein Serine-Threonine Kinase 2
"Receptor-Interacting Protein Serine-Threonine Kinase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. It can signal by associating with other CARD-signaling adaptor proteins and INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
| Descriptor ID |
D053475
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.801.500 D12.644.360.024.131.750 D12.644.360.024.500.186.500 D12.644.360.075.358.750 D12.776.157.057.006.750 D12.776.157.057.500.186.500 D12.776.476.024.139.750 D12.776.476.024.500.186.500 D12.776.476.075.358.750
|
| Concept/Terms |
Receptor-Interacting Protein Serine-Threonine Kinase 2- Receptor-Interacting Protein Serine-Threonine Kinase 2
- Receptor Interacting Protein Serine Threonine Kinase 2
- CARDIAK
- Receptor-Interacting Serine-Threonine Kinase 2
- Receptor Interacting Serine Threonine Kinase 2
- RIPK2 Protein
- RICK Protein
- CARD-containing Interleukin (IL)-1 beta Converting Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Receptor-Interacting Protein Serine-Threonine Kinase 2".
Below are MeSH descriptors whose meaning is more specific than "Receptor-Interacting Protein Serine-Threonine Kinase 2".
This graph shows the total number of publications written about "Receptor-Interacting Protein Serine-Threonine Kinase 2" by people in this website by year, and whether "Receptor-Interacting Protein Serine-Threonine Kinase 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor-Interacting Protein Serine-Threonine Kinase 2" by people in Profiles.
-
Jurynec MJ, Gavile CM, Honeggar M, Ma Y, Veerabhadraiah SR, Novak KA, Hoshijima K, Kazmers NH, Grunwald DJ. NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibility. Ann Rheum Dis. 2022 10; 81(10):1465-1473.
-
Jurynec MJ, Sawitzke AD, Beals TC, Redd MJ, Stevens J, Otterud B, Leppert MF, Grunwald DJ. A hyperactivating proinflammatory RIPK2 allele associated with early-onset osteoarthritis. Hum Mol Genet. 2018 07 01; 27(13):2383-2391.
-
Yang Z, Grinchuk V, Smith A, Qin B, Bohl JA, Sun R, Notari L, Zhang Z, Sesaki H, Urban JF, Shea-Donohue T, Zhao A. Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. Infect Immun. 2013 Jun; 81(6):1905-14.
-
Pandey AK, Yang Y, Jiang Z, Fortune SM, Coulombe F, Behr MA, Fitzgerald KA, Sassetti CM, Kelliher MA. NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis. PLoS Pathog. 2009 Jul; 5(7):e1000500.
-
Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA. NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. J Biol Chem. 2007 Dec 14; 282(50):36223-9.
-
Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC. Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains. Mol Cell Biol. 2007 Sep; 27(17):6012-25.
-
Hsu YM, Zhang Y, You Y, Wang D, Li H, Duramad O, Qin XF, Dong C, Lin X. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol. 2007 Feb; 8(2):198-205.