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Michael Thomas Heneka MD

TitleAdjunct Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressKlinische Neurowissenschaften, Universitat Bonn
Sigmund Freud Str. 33
Bon 53127
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionInfectious Diseases


    Collapse Biography 
    Collapse education and training
    Universitat Tubingen, Tubingen, , GermanyMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Eberhard J, Henning L, F?lle L, Kn?pper K, B?hringer J, Graelmann FJ, H?nschke L, Kenzler J, Brosseron F, Heneka MT, Domingos AI, Eyerich S, Lochner M, Weighardt H, Bedner P, Steinh?user C, F?rster I. Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy. Epilepsia. 2024 Nov 28. PMID: 39607395.
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    2. Heneka MT, Morgan D, Jessen F. Passive anti-amyloid ? immunotherapy in Alzheimer's disease-opportunities and challenges. Lancet. 2024 Nov 30; 404(10468):2198-2208. PMID: 39549715.
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    3. Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Sch?tze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, D?zel E, Maass A, Ziegler G. Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation. Nat Commun. 2024 Nov 13; 15(1):9815. PMID: 39537609.
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    4. Soch J, Richter A, Kizilirmak JM, Sch?tze H, Ziegler G, Altenstein S, Brosseron F, Dechent P, Fliessbach K, Freiesleben SD, Glanz W, Gref D, Heneka MT, Hetzer S, Incesoy EI, Kilimann I, Kimmich O, Kleineidam L, Kuhn E, Laske C, Lohse A, L?sebrink F, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schmid M, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Jessen F, Wagner M, D?zel E, Schott BH. Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum. Brain. 2024 Nov 04; 147(11):3789-3803. PMID: 38743817.
      Citations:    
    5. Menze I, Bernal J, Kaya P, Aki ?, Pfister M, Geisend?rfer J, Yakupov R, Coello RD, Vald?s-Hern?ndez MDC, Heneka MT, Brosseron F, Schmid MC, Glanz W, Incesoy EI, Butryn M, Rostamzadeh A, Meiberth D, Peters O, Preis L, Lammerding D, Gref D, Priller J, Spruth EJ, Altenstein S, Lohse A, Hetzer S, Schneider A, Fliessbach K, Kimmich O, Vogt IR, Wiltfang J, Bartels C, Schott BH, Hansen N, Dechent P, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Hinderer P, Scheffler K, Spottke A, Roy-Kluth N, L?sebrink F, Neumann K, Wardlaw J, Jessen F, Schreiber S, D?zel E, Ziegler G. Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study. Alzheimers Res Ther. 2024 Oct 31; 16(1):242. PMID: 39482759.
      Citations:    
    6. Tastan B, Heneka MT. The impact of neuroinflammation on neuronal integrity. Immunol Rev. 2024 Oct; 327(1):8-32. PMID: 39470038.
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    7. Aretz B, Doblhammer G, Heneka MT. The role of leukocytes in cognitive impairment due to long-term exposure to fine particulate matter: A large population-based mediation analysis. Alzheimers Dement. 2024 Oct 16. PMID: 39412000.
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    8. Wang X, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Jessen F, Rostamzadeh A, Duzel E, Glanz W, Incesoy EI, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel SJ, Kilimann I, Goerss D, Laske C, Munk MHJ, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Ramirez A, Kleineidam L, Stark M, Peters O. Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline. Neurology. 2024 Oct 22; 103(8):e209806. PMID: 39303184.
      Citations:    
    9. Karabag D, Heneka MT, Ising C. The putative contribution of cellular senescence to driving tauopathies. Trends Immunol. 2024 Oct; 45(10):837-848. PMID: 39306559.
      Citations:    
    10. Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 Aug 28; 148(1):31. PMID: 39196440.
      Citations:    
    11. Lista S, Imbimbo BP, Grasso M, Fidilio A, Emanuele E, Minoretti P, L?pez-Ortiz S, Mart?n-Hern?ndez J, Gabelle A, Caruso G, Malaguti M, Melchiorri D, Santos-Lozano A, Imbimbo C, Heneka MT, Caraci F. Tracking neuroinflammatory biomarkers in Alzheimer's disease: a strategy for individualized therapeutic approaches? J Neuroinflammation. 2024 Jul 30; 21(1):187. PMID: 39080712.
      Citations:    
    12. D?nnwald M, Krohn F, Sciarra A, Sarkar M, Schneider A, Fliessbach K, Kimmich O, Jessen F, Rostamzadeh A, Glanz W, Incesoy EI, Teipel S, Kilimann I, Goerss D, Spottke A, Brustkern J, Heneka MT, Brosseron F, L?sebrink F, H?mmerer D, D?zel E, T?nnies K, Oeltze-Jafra S, Betts MJ. Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer's Disease Dementia using ELSI-Net. bioRxiv. 2024 Jul 26. PMID: 39091766.
      Citations:    
    13. Scheiblich H, Eikens F, Wischhof L, Opitz S, J?ngling K, Cser?p C, Schmidt SV, Lambertz J, Bellande T, P?sfai B, Geck C, Spitzer J, Odainic A, Castro-Gomez S, Schwartz S, Boussaad I, Kr?ger R, Glaab E, Di Monte DA, Bano D, D?nes ?, Latz E, Melki R, Pape HC, Heneka MT. Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes. Neuron. 2024 Sep 25; 112(18):3106-3125.e8. PMID: 39059388.
      Citations:    
    14. Owona BA, Mary A, Messi AN, Ravichandran KA, Mbing JN, Pegnyemb E, Moundipa PF, Heneka MT. Biflavonoid Methylchamaejasmin and Khaya grandifoliola?Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation. Mol Neurobiol. 2024 Jul 16. PMID: 39012444.
      Citations:    
    15. Baumeister H, Vogel JW, Insel PS, Kleineidam L, Wolfsgruber S, Stark M, Gellersen HM, Yakupov R, Schmid MC, L?sebrink F, Brosseron F, Ziegler G, Freiesleben SD, Preis L, Schneider LS, Spruth EJ, Altenstein S, Lohse A, Fliessbach K, Vogt IR, Bartels C, Schott BH, Rostamzadeh A, Glanz W, Incesoy EI, Butryn M, Janowitz D, Rauchmann BS, Kilimann I, Goerss D, Munk MH, Hetzer S, Dechent P, Ewers M, Scheffler K, Wuestefeld A, Strandberg O, van Westen D, Mattsson-Carlgren N, Janelidze S, Stomrud E, Palmqvist S, Spottke A, Laske C, Teipel S, Perneczky R, Buerger K, Schneider A, Priller J, Peters O, Ramirez A, Wiltfang J, Heneka MT, Wagner M, D?zel E, Jessen F, Hansson O, Berron D. A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain. 2024 Jul 05; 147(7):2400-2413. PMID: 38654513.
      Citations:    
    16. Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease. Alzheimers Dement. 2024 08; 20(8):5132-5142. PMID: 38940303.
      Citations:    
    17. Chatterjee M, ?zdemir S, Fritz C, M?bius W, Kleineidam L, Mandelkow E, Biernat J, Dogdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, K?hn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, B?hr M, Zerr I, Fl?el A, Nestor PJ, D?zel E, Glanz W, Incesoy E, B?rger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-Gonz?lez J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo ?, Lle? A, Rojas-Garc?a R, Ill?n-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barth?lemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, H?glinger G, Hermann A, Schneider A. Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nat Med. 2024 Jun; 30(6):1771-1783. PMID: 38890531.
      Citations:    
    18. Mary A, Mancuso R, Heneka MT. Immune Activation in Alzheimer Disease. Annu Rev Immunol. 2024 Jun; 42(1):585-613. PMID: 38424470.
      Citations:    
    19. Bonhenry D, Charnley M, Gon?alves J, Hammarstr?m P, Heneka MT, Itzhaki R, Lambert JC, Mannan M, Baig AM, Middeldorp J, Nystr?m S, Reynolds NP, Stefanatou M, Berryman JT. SARS-CoV-2 infection as a cause of neurodegeneration. Lancet Neurol. 2024 Jun; 23(6):562-563. PMID: 38760096.
      Citations:    
    20. Heneka MT. TREM1 is the new kid on the block for the aging-associated innate immune response and Alzheimer's disease. Nat Immunol. 2024 Jun; 25(6):938-940. PMID: 38831103.
      Citations:    
    21. D?rner M, Seebach K, Heneka MT, Menze I, von K?nel R, Euler S, Schreiber F, Arndt P, Neumann K, Hildebrand A, John AC, Tyndall A, Kirchebner J, Tacik P, Jansen R, Grimm A, Henneicke S, Perosa V, Meuth SG, Peters O, Hellmann-Regen J, Preis L, Priller J, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Jessen F, Rostamzadeh A, Glanz W, Schulze JB, Schiebler SLF, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Munk MH, Spottke A, Roy-Kluth N, Wagner M, Frommann I, L?sebrink F, Dechent P, Hetzer S, Scheffler K, Kleineidam L, Stark M, Schmid M, Ers?zl? E, Brosseron F, Ewers M, Schott BH, D?zel E, Ziegler G, Mattern H, Schreiber S, Bernal J. Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age-Results from the Multicentre Observational DELCODE Study. Diagnostics (Basel). 2024 Apr 30; 14(9). PMID: 38732354.
      Citations:    
    22. Bl?meke L, Rehn F, Kraemer-Schulien V, Kutzsche J, Pils M, Bujnicki T, Lewczuk P, Kornhuber J, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Lohse A, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Rostamzadeh A, D?zel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Kleineidam L, Stark M, Schmid M, Jessen F, Bannach O, Willbold D, Peters O. A? oligomers peak in early stages of Alzheimer's disease preceding tau pathology. Alzheimers Dement (Amst). 2024 Apr-Jun; 16(2):e12589. PMID: 38666085.
      Citations:    
    23. Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, Kimmich O, Wiltfang J, Bartels C, Hansen N, Jessen F, Rostamzadeh A, D?zel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Wagner M, Roeske S, Heneka MT, Brosseron F, Ramirez A, Dobisch L, Wolfsgruber S, Kleineidam L, Yakupov R, Stark M, Schmid MC, Berger M, Hetzer S, Dechent P, Scheffler K, Petzold GC, Schneider A, Effland A, Radbruch A. Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Invest Radiol. 2024 Sep 01; 59(9):667-676. PMID: 38652067.
      Citations:    
    24. Castro-Gomez S, Heneka MT. Innate immune activation in neurodegenerative diseases. Immunity. 2024 Apr 09; 57(4):790-814. PMID: 38599171.
      Citations:    
    25. Brown GC, Heneka MT. The endotoxin hypothesis of Alzheimer's disease. Mol Neurodegener. 2024 Apr 01; 19(1):30. PMID: 38561809.
      Citations:    
    26. Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2632-2652. PMID: 38375983.
      Citations:    
    27. Talavera And?jar B, Mary A, Venegas C, Cheng T, Zaslavsky L, Bolton EE, Heneka MT, Schymanski EL. Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients? Environ Sci Technol. 2024 Mar 05; 58(9):4181-4192. PMID: 38373301.
      Citations:    
    28. Schuster J, Dreyhaupt J, M?nkem?ller K, Dupuis L, Dieterl? S, Weishaupt JH, Kassubek J, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Johannesen S, G?ricke B, Witzel S, Dorst J, Ludolph AC. In-depth analysis of data from the RAS-ALS study reveals new insights in rasagiline treatment for amyotrophic lateral sclerosis. Eur J Neurol. 2024 Apr; 31(4):e16204. PMID: 38240416.
      Citations:    Fields:    
    29. Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marqui? M, Boada M, Sotolongo O, Gonz?lez PG, Puerta R, D?zel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry. 2024 Apr; 29(4):992-1004. PMID: 38216727.
      Citations:    Fields:    
    30. Teipel SJ, Dyrba M, Kleineidam L, Brosseron F, Levin F, Bruno D, Buerger K, Cosma N, Schneider LS, D?zel E, Glanz W, Fliessbach K, Janowitz D, Kilimann I, Laske C, Munk MH, Maier F, Peters O, Pomara N, Perneczky R, Rauchmann BS, Priller J, Ramirez A, Roy N, Schneider A, Spottke A, Spruth EJ, Roeske S, Wagner M, Wiltfang J, Wolfsgruber S, Bartels C, Jessen F, Heneka MT. Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline. Alzheimers Dement (Amst). 2024 Jan-Mar; 16(1):e12510. PMID: 38213951.
      Citations:    
    31. Ravichandran KA, Heneka MT. Inflammasomes in neurological disorders - mechanisms and therapeutic potential. Nat Rev Neurol. 2024 02; 20(2):67-83. PMID: 38195712.
      Citations:    Fields:    Translation:Humans
    32. Sannemann L, Bartels C, Brosseron F, Buerger K, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Lammerding D, Laske C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Schild AK, Schneider A, Schneider LS, Spottke A, Spruth EJ, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals. J Alzheimers Dis. 2024; 100(1):193-205. PMID: 38848176.
      Citations:    
    33. Budinger D, Baker V, Heneka MT. Tunneling Nanotubes in the Brain. Results Probl Cell Differ. 2024; 73:203-227. PMID: 39242381.
      Citations:    
    34. Dadwal S, Heneka MT. Microglia heterogeneity in health and disease. FEBS Open Bio. 2024 02; 14(2):217-229. PMID: 37945346.
      Citations: 2     Fields:    Translation:HumansCells
    35. Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Hinderer P, Incesoy EI, Janowitz D, Kilimann I, Kimmich O, Laske C, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Sanzenbacher C, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Vogt IR, Wiltfang J, Duzel E, Jessen F, Wagner M. Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline. Neurology. 2023 Nov 21; 101(21):e2185-e2196. PMID: 37821235.
      Citations: 1     Fields:    Translation:Humans
    36. Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Janowitz D, Kilimann I, Lohse A, Munk MH, Rauchmann BS, Rostamzadeh A, Roy N, Spruth EJ, Dechent P, Heneka MT, Hetzer S, Ramirez A, Scheffler K, Buerger K, Laske C, Perneczky R, Peters O, Priller J, Schneider A, Spottke A, Teipel S, D?zel E, Jessen F, Wiltfang J, Schott BH, Kizilirmak JM. Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression. Int J Geriatr Psychiatry. 2023 10; 38(10):e6007. PMID: 37800601.
      Citations: 1     Fields:    Translation:Humans
    37. Teipel SJ, Dyrba M, Levin F, Altenstein S, Berger M, Beyle A, Brosseron F, Buerger K, Burow L, Dobisch L, Ewers M, Fliessbach K, Frommann I, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Incesoy EI, Janowitz D, Keles D, Kilimann I, Laske C, Lohse A, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rostamzadeh A, Roy N, Schmid M, Schneider A, Spottke A, Spruth EJ, Wiltfang J, D?zel E, Jessen F, Kleineidam L, Wagner M. Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach. J Alzheimers Dis Rep. 2023; 7(1):1055-1076. PMID: 37849637.
      Citations:    
    38. Bartsch T, Berg D, Heneka M, Leypoldt F. [Parkinson's and Alzheimer's disease as system-wide neurodegenerative disorders]. Nervenarzt. 2023 Oct; 94(10):875-884. PMID: 37672086.
      Citations:    Fields:    
    39. Kapadia A, Theil S, Opitz S, Villacampa N, Beckert H, Schoch S, Heneka MT, Kumar S, Walter J. Phosphorylation-state dependent intraneuronal sorting of A? differentially impairs autophagy and the endo-lysosomal system. Autophagy. 2024 01; 20(1):166-187. PMID: 37642583.
      Citations:    Fields:    Translation:Cells
    40. Karabag D, Scheiblich H, Griep A, Santarelli F, Schwartz S, Heneka MT, Ising C. Characterizing microglial senescence: Tau as a key player. J Neurochem. 2023 08; 166(3):517-533. PMID: 37278117.
      Citations: 2     Fields:    Translation:AnimalsCells
    41. Walker KA, Le Page LM, Terrando N, Duggan MR, Heneka MT, Bettcher BM. The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap. Mol Neurodegener. 2023 06 05; 18(1):37. PMID: 37277738.
      Citations: 4     Fields:    Translation:Humans
    42. Bendella Z, Widmann CN, Layer JP, Layer YL, Haase R, Sauer M, Bieler L, Lehnen NC, Paech D, Heneka MT, Radbruch A, Schmeel FC. Brain Volume Changes after COVID-19 Compared to Healthy Controls by Artificial Intelligence-Based MRI Volumetry. Diagnostics (Basel). 2023 May 12; 13(10). PMID: 37238200.
      Citations:    
    43. Stratoulias V, Ruiz R, Kanatani S, Osman AM, Keane L, Armengol JA, Rodr?guez-Moreno A, Murgoci AN, Garc?a-Dom?nguez I, Alonso-Bellido I, Gonz?lez Ib??ez F, Picard K, V?zquez-Cabrera G, Posada-P?rez M, Vernoux N, Tejera D, Grabert K, Cheray M, Gonz?lez-Rodr?guez P, P?rez-Villegas EM, Mart?nez-Gallego I, Lastra-Romero A, Brodin D, Avila-Cari?o J, Cao Y, Airavaara M, Uhl?n P, Heneka MT, Tremblay M?, Blomgren K, Venero JL, Joseph B. ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Nat Neurosci. 2023 06; 26(6):1008-1020. PMID: 37169859.
      Citations: 5     Fields:    Translation:AnimalsCells
    44. Nemy M, Dyrba M, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Goerss D, Heneka MT, Hetzer S, Incesoy EI, Janowitz D, Kilimann I, Laske C, Maier F, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, R?ske S, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Yakupov R, Eriksdotter M, Westman E, Stepankova O, Vyslouzilova L, D?zel E, Jessen F, Teipel SJ, Ferreira D. Cholinergic white matter pathways along the Alzheimer's disease continuum. Brain. 2023 05 02; 146(5):2075-2088. PMID: 36288546.
      Citations: 3     Fields:    Translation:Humans
    45. Ising C, Heneka MT. Chronic inflammation: a potential target in tauopathies. Lancet Neurol. 2023 05; 22(5):371-373. PMID: 37059499.
      Citations:    Fields:    Translation:Humans
    46. Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Pi?a-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC. APOE and immunity: Research highlights. Alzheimers Dement. 2023 06; 19(6):2677-2696. PMID: 36975090.
      Citations: 4     Fields:    Translation:HumansCells
    47. Braatz C, Komes MP, Ravichandran KA, de Fragas MG, Griep A, Schwartz S, McManus RM, Heneka MT. NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro. J Neurochem. 2024 Oct; 168(10):3467-3481. PMID: 36799439.
      Citations: 1     Fields:    
    48. Heinzinger N, Maass A, Berron D, Yakupov R, Peters O, Fiebach J, Villringer K, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Jessen F, Maier F, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Killimann I, G?er? D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Dobisch L, Ewers M, Dechent P, Haynes JD, Scheffler K, Wolfsgruber S, Kleineidam L, Schmid M, Berger M, D?zel E, Ziegler G. Exploring the ATN classification system using brain morphology. Alzheimers Res Ther. 2023 03 13; 15(1):50. PMID: 36915139.
      Citations: 1     Fields:    Translation:Humans
    49. Yildirim Z, Delen F, Berron D, Baumeister H, Ziegler G, Sch?tze H, Glanz W, Dobisch L, Peters O, Freiesleben SD, Schneider LS, Priller J, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Meiberth D, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Munk MH, Spottke A, Roy N, Heneka M, Brosseron F, Wagner M, Roeske S, Ramirez A, Ewers M, Dechent P, Hetzer S, Scheffler K, Kleineidam L, Wolfsgruber S, Yakupov R, Schmid M, Berger M, Gurvit H, Jessen F, Duzel E. Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2. Alzheimers Res Ther. 2023 02 28; 15(1):43. PMID: 36855049.
      Citations:    Fields:    Translation:Humans
    50. de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hern?ndez I, Montrreal L, Ant?nez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, Gonz?lez-Perez A, Calero M, Franco-Mac?as E, Mac?as J, Blesa R, Cervera-Carles L, Men?ndez-Gonz?lez M, Frank-Garc?a A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, Garc?a-Madrona S, Garc?a-Gonz?lez P, Alarc?n-Mart?n E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, P?rez-Cord?n A, Benussi A, R?bano A, Padovani A, Squassina A, de Mendon?a A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-G?mez A, Mart?n Montes A, Sanabria ?, DeStefano AL, Schneider A, Haapasalo A, Kinhult St?hlbom A, Tybj?rg-Hansen A, Hartmann AM, Spottke A, Corbat?n-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Mart?nez Rodr?guez C, Mu?oz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Gr?nblatt E, Dardiotis E, D?zel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, K???kali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selb?k G, Ortega G, Ch?ne G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Flie?bach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, L?wenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal S?nchez-Arjona M, Dalmasso MC, Mart?nez-Larrad MT, Arcaro M, N?then MM, Fern?ndez-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Boss? P, Caffarra P, Dionigi Rossi P, Sakka P, Mecocci P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, H?gg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL, Kehoe PG, Garcia-Ribas G, S?nchez-Juan P, Pastor P, P?rez-Tur J, Pi?ol-Ripoll G, Lopez de Munain A, Garc?a-Alberca JM, Bullido MJ, ?lvarez V, Lle? A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marqui? M, S?ez ME, Carracedo ?, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, S?nchez-Valle R, Serrano-R?os M, Orellana A, T?rraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarim?n J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun. 2023 Feb 09; 14(1):716. PMID: 36759603.
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    51. Heneka MT. ApoE4 makes microglia trem2bling. Neuron. 2023 01 18; 111(2):142-144. PMID: 36657395.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    52. Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, H?sler LM, McManus R, Ising C, R?ske S, Peters O, Cosma NC, Schneider LS, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Buerger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, G?r? D, Laske C, Munk MH, D?zel E, Yakupow R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Spottke A, Ramirez A, Mengel D, Synofzik M, Jucker M, Latz E, Jessen F, Wagner M, Heneka MT. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimers Res Ther. 2023 01 12; 15(1):13. PMID: 36631909.
      Citations: 5     Fields:    Translation:Humans
    53. Ersoezlue E, Perneczky R, Tato M, Utecht J, Kurz C, H?ckert J, Guersel S, Burow L, Koller G, Stoecklein S, Keeser D, Papazov B, Totzke M, Ballarini T, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Laske C, Maier F, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Unterfeld C, Wagner M, Wang X, Wiltfang J, Wolfsgruber S, Yakupov R, Duezel E, Jessen F, Rauchmann BS. A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum. J Alzheimers Dis. 2023; 92(3):925-940. PMID: 36806502.
      Citations:    Fields:    Translation:Humans
    54. Raku?a E, Fink A, Tamg?ney G, Heneka MT, Doblhammer G. Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case-Control Study Based on German Health Claims Data. J Alzheimers Dis. 2023; 93(4):1329-1339. PMID: 37182873.
      Citations: 1     Fields:    Translation:Humans
    55. Mercan D, Heneka MT. The Contribution of the Locus Coeruleus-Noradrenaline System Degeneration during the Progression of Alzheimer's Disease. Biology (Basel). 2022 Dec 14; 11(12). PMID: 36552331.
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    56. Kleineidam L, Wolfsgruber S, Weyrauch AS, Zulka LE, Forstmeier S, Roeske S, van den Bussche H, Kaduszkiewicz H, Wiese B, Weyerer S, Werle J, Fuchs A, Pentzek M, Brettschneider C, K?nig HH, Weeg D, Bickel H, Luppa M, Rodriguez FS, Freiesleben SD, Erdogan S, Unterfeld C, Peters O, Spruth EJ, Altenstein S, Lohse A, Priller J, Fliessbach K, Kobeleva X, Schneider A, Bartels C, Schott BH, Wiltfang J, Maier F, Glanz W, Incesoy EI, Butryn M, D?zel E, Buerger K, Janowitz D, Ewers M, Rauchmann BS, Perneczky R, Kilimann I, G?r? D, Teipel S, Laske C, Munk MHJ, Spottke A, Roy N, Brosseron F, Heneka MT, Ramirez A, Yakupov R, Scherer M, Maier W, Jessen F, Riedel-Heller SG, Wagner M. Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve. Front Psychol. 2022; 13:957308. PMID: 36571008.
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    57. Castro-Gomez S, Binder J, Schievelkamp AH, Heneka MT. CNS Superficial Siderosis Mimicking a Motor Neuron Disease. Brain Sci. 2022 Nov 16; 12(11). PMID: 36421882.
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    58. Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Br?ne B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, Gonz?lez B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 11 02; 110(21):3458-3483. PMID: 36327895.
      Citations: 225     Fields:    Translation:Cells
    59. Ersoezlue E, Rauchmann BS, Schneider-Axmann T, Wagner M, Ballarini T, Tato M, Utecht J, Kurz C, Papazov B, Guersel S, Burow L, Koller G, St?cklein S, Keeser D, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dechent P, Dobisch L, Ewers M, Fliessbach K, Frommann I, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Wolfsgruber S, Yakupov R, Duezel E, Jessen F, Perneczky R. Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease. Neurobiol Aging. 2023 02; 122:33-44. PMID: 36476760.
      Citations: 2     Fields:    Translation:Humans
    60. Henning L, Antony H, Breuer A, M?ller J, Seifert G, Audinat E, Singh P, Brosseron F, Heneka MT, Steinh?user C, Bedner P. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. 2023 02; 71(2):168-186. PMID: 36373840.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    61. Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, K???kali F, Sung YJ, Tes? N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo ?, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, D?zel E, Fladby T, Fortea J, Fr?lich L, Garc?a-Gonz?lez P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hern?ndez I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lle? A, de Munain AL, Lopez-Garcia S, Maier W, Marqui? M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, N?then MM, Orellana A, P?lhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selb?k G, Selnes P, Shadrin A, Skoog I, Soininen H, T?rraga L, Teipel S, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarim?n J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 11; 144(5):821-842. PMID: 36066633.
      Citations: 18     Fields:    Translation:Humans
    62. Krieger J, Frackowiak M, Berger M, Heneka MT, Jacobs AH. Falls at advanced age - The importance to search for benign paroxysmal positional vertigo (BPPV). Exp Gerontol. 2022 08; 165:111868. PMID: 35700849.
      Citations:    Fields:    Translation:Humans
    63. Billette OV, Ziegler G, Aruci M, Sch?tze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, G?er? D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, R?ske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, D?zel E, Maass A. Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. 2022 08 23; 99(8):e775-e788. PMID: 35995589.
      Citations: 10     Fields:    Translation:Humans
    64. Berron D, Ziegler G, Vieweg P, Billette O, G?sten J, Grande X, Heneka MT, Schneider A, Teipel S, Jessen F, Wagner M, D?zel E. Feasibility of Digital Memory Assessments in an Unsupervised and Remote Study Setting. Front Digit Health. 2022; 4:892997. PMID: 35721797.
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    65. D?zel E, Ziegler G, Berron D, Maass A, Sch?tze H, Cardenas-Blanco A, Glanz W, Metzger C, Dobisch L, Reuter M, Spottke A, Brosseron F, Fliessbach K, Heneka MT, Laske C, Peters O, Priller J, Spruth EJ, Ramirez A, Speck O, Schneider A, Teipel S, Kilimann I, Jens W, Schott BH, Preis L, Gref D, Maier F, Munk MH, Roy N, Ballarini T, Yakupov R, Haynes JD, Dechent P, Scheffler K, Wagner M, Jessen F. Amyloid pathology but not APOE e4 status is permissive for tau-related hippocampal dysfunction. Brain. 2022 05 24; 145(4):1473-1485. PMID: 35352105.
      Citations: 7     Fields:    Translation:Humans
    66. Jessen F, Wolfsgruber S, Kleineindam L, Spottke A, Altenstein S, Bartels C, Berger M, Brosseron F, Daamen M, Dichgans M, Dobisch L, Ewers M, Fenski F, Fliessbach K, Freiesleben SD, Glanz W, G?r? D, G?rsel S, Janowitz D, Kilimann I, Kobeleva X, Lohse A, Maier F, Metzger C, Munk M, Preis L, Sanzenbacher C, Spruth E, Rauchmann B, Vukovich R, Yakupov R, Weyrauch AS, Ziegler G, Schmid M, Laske C, Perneczky R, Schneider A, Wiltfang J, Teipel S, B?rger K, Priller J, Peters O, Ramirez A, Boecker H, Heneka MT, Wagner M, D?zel E. Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers. Alzheimers Dement. 2023 02; 19(2):487-497. PMID: 35451563.
      Citations: 10     Fields:    Translation:Humans
    67. Whitson HE, Colton C, El Khoury J, Gate D, Goate A, Heneka MT, Kaddurah-Daouk R, Klein RS, Shinohara ML, Sisodia S, Spudich SS, Stevens B, Tanzi R, Ting JP, Garden G. Infection and inflammation: New perspectives on Alzheimer's disease. Brain Behav Immun Health. 2022 Jul; 22:100462. PMID: 36118272.
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    68. Bellenguez C, K???kali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarc?n-Mart?n E, Alcolea D, Alegret M, Alvarez I, ?lvarez V, Armstrong NJ, Tsolaki A, Ant?nez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Boss? P, Br?then G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, B?rger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo ?, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-G?mez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, D?zel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fern?ndez-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Flie?bach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Mac?as E, Bullido MJ, Frank-Garc?a A, Froelich L, Fulton-Howard B, Galimberti D, Garc?a-Alberca JM, Garc?a-Gonz?lez P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, Gonz?lez-P?rez A, Graff C, Grande G, Green E, Grimmer T, Gr?nblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hern?ndez I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, St?hlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lle? A, Longstreth W, Lopez O, de Munain AL, Love S, L?wemark M, Luckcuck L, Lunetta KL, Ma Y, Mac?as J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marqui? M, Marshall R, Martin ER, Montes AM, Rodr?guez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Men?ndez-Gonz?lez M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, N?then MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, P?rez-Cord?n A, P?rez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Pi?ol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, R?bano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, S?ez ME, Sakka P, Saltvedt I, Sanabria ?, S?nchez-Arjona MB, Sanchez-Garcia F, Juan PS, S?nchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selb?k G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, T?rraga L, Tes? N, Thalamuthu A, Thomas T, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet. 2022 04; 54(4):412-436. PMID: 35379992.
      Citations: 331     Fields:    Translation:Humans
    69. Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Ch?telat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerstr?m M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, F?rster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fr?hlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, G?mez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lle? A, L?wenmark M, Madsen K, Maier W, Marcusson J, Marqui? M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendon?a A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodr?guez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, R?ther E, Ruiz A, Sabri O, Sakhardande J, S?nchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schr?der J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ?K, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurol. 2022 03 01; 79(3):228-243. PMID: 35099509.
      Citations: 54     Fields:    Translation:Humans
    70. Perea JR, Bol?s M, Cuadros R, Garc?a E, Garc?a-Escudero V, Hern?ndez F, McManus RM, Heneka MT, Avila J. p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function. Mol Neurobiol. 2022 Mar; 59(3):1632-1648. PMID: 35006531.
      Citations: 1     Fields:    Translation:HumansCells
    71. Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Gonz?lez PG, McManus RM, Ising C, Santarelli F, Kolbe CC, H?sler LM, Wolfsgruber S, Marqui? M, Boada M, Orellana A, de Rojas I, R?ske S, Peters O, Cosma NC, Cetindag A, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, B?rger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, D?zel E, Yakupov R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Teunissen CE, Marchant NL, Spottke A, Jucker M, Latz E, Wagner M, Mengel D, Synofzik M, Jessen F, Ramirez A, Ruiz A, Heneka MT. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. 2022 03 16; 110(6):1009-1022.e4. PMID: 34995486.
      Citations: 13     Fields:    Translation:Humans
    72. Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, D?zel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ram?rez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2022; 85(3):1267-1282. PMID: 34924387.
      Citations: 6     Fields:    Translation:Humans
    73. Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, R?ske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Flie?bach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, D?zel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M. Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022; 87(2):545-555. PMID: 35275535.
      Citations: 4     Fields:    Translation:Humans
    74. Ravichandran KA, Heneka MT. Inflammasome activation in neurodegenerative diseases. Essays Biochem. 2021 12 22; 65(7):885-904. PMID: 34846519.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    75. Janssen O, Jansen WJ, Vos SJB, Boada M, Parnetti L, Gabryelewicz T, Fladby T, Molinuevo JL, Villeneuve S, Hort J, Epelbaum S, Lle? A, Engelborghs S, van der Flier WM, Landau S, Popp J, Wallin A, Scheltens P, Rikkert MO, Snyder PJ, Rowe C, Ch?telat G, Ru?z A, Marqui? M, Chipi E, Wolfsgruber S, Heneka M, Boecker H, Peters O, Jarholm J, Rami L, Tort-Merino A, Binette AP, Poirier J, Rosa-Neto P, Cerman J, Dubois B, Teichmann M, Alcolea D, Fortea J, S?nchez-Saudin?s MB, Ebenau J, Pocnet C, Eckerstr?m M, Thompson L, Villemagne V, Buckley R, Burnham S, Delarue M, Freund-Levi Y, Wallin ?K, Ramakers I, Tsolaki M, Soininen H, Hampel H, Spiru L, Tijms B, Ossenkoppele R, Verhey FRJ, Jessen F, Visser PJ. Characteristics of subjective cognitive decline associated with amyloid positivity. Alzheimers Dement. 2022 10; 18(10):1832-1845. PMID: 34877782.
      Citations: 9     Fields:    Translation:Humans
    76. Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, Terrando N, Willette AA, Willette SA. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimers Dement. 2022 05; 18(5):1038-1046. PMID: 34874605.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    77. Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662. PMID: 34825707.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    78. Dyrba M, Hanzig M, Altenstein S, Bader S, Ballarini T, Brosseron F, Buerger K, Cantr? D, Dechent P, Dobisch L, D?zel E, Ewers M, Fliessbach K, Glanz W, Haynes JD, Heneka MT, Janowitz D, Keles DB, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann B, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Weber MA, Ertl-Wagner B, Wagner M, Wiltfang J, Jessen F, Teipel SJ. Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease. Alzheimers Res Ther. 2021 11 23; 13(1):191. PMID: 34814936.
      Citations: 9     Fields:    Translation:Humans
    79. Castro-Gomez S, Radermacher B, Tacik P, Mirandola SR, Heneka MT, Weydt P. Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis. Brain Commun. 2021; 3(4):fcab274. PMID: 34993474.
      Citations:    
    80. Widmann CN, Wieberneit M, Bieler L, Bernsen S, Gr?fenk?mper R, Brosseron F, Schmeel C, Tacik P, Skowasch D, Radbruch A, Heneka MT. Longitudinal Neurocognitive and Pulmonological Profile of Long COVID-19: Protocol for the COVIMMUNE-Clin Study. JMIR Res Protoc. 2021 Nov 11; 10(11):e30259. PMID: 34559059.
      Citations:    
    81. Manabe T, Heneka MT. Cerebral dysfunctions caused by sepsis during ageing. Nat Rev Immunol. 2022 07; 22(7):444-458. PMID: 34764472.
      Citations: 29     Fields:    Translation:Humans
    82. Bettcher BM, Tansey MG, Doroth?e G, Heneka MT. Publisher Correction: Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nat Rev Neurol. 2021 Nov; 17(11):724. PMID: 34625724.
      Citations: 2     Fields:    
    83. Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J, Walter J. TREM2 modulates differential deposition of modified and non-modified A? species in extracellular plaques and intraneuronal deposits. Acta Neuropathol Commun. 2021 10 18; 9(1):168. PMID: 34663480.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    84. Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, Biederbick Y, Halle A, Salomoni P, Heneka MT, Capasso M. mTOR-dependent translation amplifies microglia priming in aging mice. J Clin Invest. 2021 10 15; 131(20). PMID: 34651589.
      Citations: 2     Fields:    
    85. Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimoglu C, Wirths O, Bickeb?ller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger CD, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, D?zel E, Jessen F, Rizzoli SO, Zimmermann WH, Schulze TG, Falkai P, Sananbenesi F, Fischer A. A microRNA signature that correlates with cognition and is a target against cognitive decline. EMBO Mol Med. 2021 11 08; 13(11):e13659. PMID: 34633146.
      Citations: 18     Fields:    Translation:Humans
    86. Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R. Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 10 01; 31(11):4901-4915. PMID: 34080613.
      Citations: 6     Fields:    Translation:Humans
    87. Rueda-Carrasco J, Martin-Bermejo MJ, Pereyra G, Mateo MI, Borroto A, Brosseron F, Kummer MP, Schwartz S, L?pez-Atalaya JP, Alarcon B, Esteve P, Heneka MT, Bovolenta P. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. EMBO Rep. 2021 11 04; 22(11):e51696. PMID: 34569685.
      Citations: 14     Fields:    Translation:AnimalsCells
    88. Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell. 2021 09 30; 184(20):5089-5106.e21. PMID: 34555357.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    89. Jiang S, Maphis NM, Binder J, Chisholm D, Weston L, Duran W, Peterson C, Zimmerman A, Mandell MA, Jett SD, Bigio E, Geula C, Mellios N, Weick JP, Rosenberg GA, Latz E, Heneka MT, Bhaskar K. Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway. Cell Rep. 2021 09 21; 36(12):109720. PMID: 34551296.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    90. Bettcher BM, Tansey MG, Doroth?e G, Heneka MT. Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nat Rev Neurol. 2021 11; 17(11):689-701. PMID: 34522039.
      Citations: 96     Fields:    Translation:HumansAnimals
    91. Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MT. Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies. J Immunol. 2021 10 15; 207(8):2143-2154. PMID: 34507948.
      Citations: 30     Fields:    Translation:AnimalsCells
    92. Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified A? species. Glia. 2021 12; 69(12):2917-2932. PMID: 34427354.
      Citations: 8     Fields:    Translation:AnimalsCells
    93. Manabe T, R?cz I, Schwartz S, Oberle L, Santarelli F, Emmrich JV, Neher JJ, Heneka MT. Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. J Neurochem. 2021 11; 159(3):525-542. PMID: 34379806.
      Citations: 13     Fields:    Translation:AnimalsCells
    94. Aretz B, Janssen F, Vonk JM, Heneka MT, Boezen HM, Doblhammer G. Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes. Environ Res. 2021 10; 201:111533. PMID: 34153335.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    95. Bergstr?m S, Remnest?l J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, L?wenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellg?rd B, Brosseron F, Heneka MT, Bosch B, Sanchez-Valle R, M?nberg A, Svenningsson P, Nilsson P. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Ann Clin Transl Neurol. 2021 07; 8(7):1456-1470. PMID: 34129723.
      Citations: 9     Fields:    Translation:Humans
    96. Ballarini T, Melo van Lent D, Brunner J, Schr?der A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Hauser D, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk M, Perneczky R, Peters O, Priller J, Ramirez A, Rauchmann B, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel SJ, Vukovich R, Wiltfang J, Jessen F, Wagner M. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. 2021 06 15; 96(24):e2920-e2932. PMID: 33952652.
      Citations: 39     Fields:    
    97. de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hern?ndez I, Montrreal L, Ant?nez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, Gonz?lez-Perez A, Calero M, Franco-Mac?as E, Mac?as J, Blesa R, Cervera-Carles L, Men?ndez-Gonz?lez M, Frank-Garc?a A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, Garc?a-Madrona S, Garc?a-Gonz?lez P, Alarc?n-Mart?n E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, P?rez-Cord?n A, Benussi A, R?bano A, Padovani A, Squassina A, de Mendon?a A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-G?mez A, Mart?n Montes A, Sanabria ?, DeStefano AL, Schneider A, Haapasalo A, Kinhult St?hlbom A, Tybj?rg-Hansen A, Hartmann AM, Spottke A, Corbat?n-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Mart?nez Rodr?guez C, Mu?oz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Gr?nblatt E, Dardiotis E, D?zel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, K???kali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selb?k G, Ortega G, Ch?ne G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Flie?bach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, L?wenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal S?nchez-Arjona M, Dalmasso MC, Mart?nez-Larrad MT, Arcaro M, N?then MM, Fern?ndez-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Boss? P, Caffarra P, Dionigi Rossi P, Sakka P, Mecocci P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, H?gg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL, Kehoe PG, Garcia-Ribas G, S?nchez-Juan P, Pastor P, P?rez-Tur J, Pi?ol-Ripoll G, Lopez de Munain A, Garc?a-Alberca JM, Bullido MJ, ?lvarez V, Lle? A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marqui? M, S?ez ME, Carracedo ?, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, S?nchez-Valle R, Serrano-R?os M, Orellana A, T?rraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarim?n J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun. 2021 06 07; 12(1):3417. PMID: 34099642.
      Citations: 72     Fields:    Translation:Humans
    98. Odoj K, Brawek B, Asavapanumas N, Mojtahedi N, Heneka MT, Garaschuk O. In vivo mechanisms of cortical network dysfunction induced by systemic inflammation. Brain Behav Immun. 2021 08; 96:113-126. PMID: 34052361.
      Citations: 6     Fields:    Translation:AnimalsCells
    99. Nitsch L, Petzinna S, Zimmermann J, Schneider L, Krauthausen M, Heneka MT, Getts DR, Becker A, M?ller M. Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model. J Neuroinflammation. 2021 Apr 27; 18(1):101. PMID: 33906683.
      Citations: 7     Fields:    Translation:AnimalsCells
    100. Hansen N, Singh A, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dobisch L, Dechent P, Ertl-Wagner BB, Fliessbach K, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wiltfang J, Duezel E, Jessen F, Goya-Maldonado R. Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline. Front Aging Neurosci. 2021; 13:626974. PMID: 33967736.
      Citations:    
    101. Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. Author Correction: A guiding map for inflammation. Nat Immunol. 2021 Feb; 22(2):254. PMID: 33288963.
      Citations: 3     Fields:    
    102. Ribon M, Leone C, Chiot A, Berriat F, Rampanana M, Cottin J, Bohl D, Millecamps S, Lobsiger CS, Heneka MT, Boill?e S. Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice. Neurobiol Aging. 2021 05; 101:181-186. PMID: 33626479.
      Citations: 1     Fields:    Translation:AnimalsCells
    103. Kumar S, Kapadia A, Theil S, Joshi P, Riffel F, Heneka MT, Walter J. Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated A? Species in a Mouse Model of Alzheimer's Disease. Front Mol Neurosci. 2020; 13:619639. PMID: 33519377.
      Citations:    
    104. Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, Biederbick Y, Halle A, Salomoni P, Heneka MT, Capasso M. mTOR-dependent translation amplifies microglia priming in aging mice. J Clin Invest. 2021 01 04; 131(1). PMID: 33108356.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    105. Lage C, Gonz?lez-Su?rez A, Alcalde-Hierro MP, Sampedro-Gonz?lez MI, Villanueva-Eguaras M?, S?nchez-Crespo MR, Widmann C, Brosseron F, Pozueta A, L?pez-Garc?a S, Garc?a-Mart?nez M, Kazimierczak M, Bravo-Gonz?lez M, Fern?ndez-Rodr?guez A, Drake-P?rez M, Irure-Ventura J, L?pez-Hoyos M, Rodr?guez-Rodr?guez E, Heneka MT, S?nchez-Juan P. Major Surgery Affects Memory in Individuals with Cerebral Amyloid-? Pathology. J Alzheimers Dis. 2021; 79(2):863-874. PMID: 33361588.
      Citations: 5     Fields:    Translation:Humans
    106. Fritze T, Doblhammer G, Widmann CN, Heneka MT. Time course of dementia following sepsis in German health claims data. Neurol Neuroimmunol Neuroinflamm. 2021 01; 8(1). PMID: 33293458.
      Citations: 4     Fields:    Translation:Humans
    107. Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, Glanz W, Dylan Haynes J, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Jakob Spruth E, Tscheuschler M, Vukovich R, Wiltfang J, Jessen F, Teipel S, Grothe MJ. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage Clin. 2020; 28:102495. PMID: 33395986.
      Citations: 10     Fields:    Translation:Humans
    108. Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, Metzger CD, Munk MHJ, Perneczky R, Peters O, Polcher A, Priller J, Rauchmann B, R?sch C, Rudolph J, Schneider A, Spottke A, Spruth EJ, Teipel S, Vukovich R, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimers Res Ther. 2020 10 16; 12(1):131. PMID: 33066827.
      Citations: 5     Fields:    Translation:Humans
    109. Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation. J Neurochem. 2021 06; 157(6):2210-2224. PMID: 32894885.
      Citations: 8     Fields:    Translation:Humans
    110. Finsterwalder S, Vlegels N, Gesierich B, Araque Caballero M?, Weaver NA, Franzmeier N, Georgakis MK, Konieczny MJ, Koek HL, Karch CM, Graff-Radford NR, Salloway S, Oh H, Allegri RF, Chhatwal JP, Jessen F, D?zel E, Dobisch L, Metzger C, Peters O, Incesoy EI, Priller J, Spruth EJ, Schneider A, Flie?bach K, Buerger K, Janowitz D, Teipel SJ, Kilimann I, Laske C, Buchmann M, Heneka MT, Brosseron F, Spottke A, Roy N, Ertl-Wagner B, Scheffler K, Seo SW, Kim Y, Na DL, Kim HJ, Jang H, Ewers M, Levin J, Schmidt R, Pasternak O, Dichgans M, Biessels GJ, Duering M. Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimers Dement. 2020 11; 16(11):1504-1514. PMID: 32808747.
      Citations: 23     Fields:    Translation:Humans
    111. Wolfsgruber S, Kleineidam L, Guski J, Polcher A, Frommann I, Roeske S, Spruth EJ, Franke C, Priller J, Kilimann I, Teipel S, Buerger K, Janowitz D, Laske C, Buchmann M, Peters O, Menne F, Fuentes Casan M, Wiltfang J, Bartels C, D?zel E, Metzger C, Glanz W, Thelen M, Spottke A, Ramirez A, Kofler B, Flie?bach K, Schneider A, Heneka MT, Brosseron F, Meiberth D, Jessen F, Wagner M. Minor neuropsychological deficits in patients with subjective cognitive decline. Neurology. 2020 09 01; 95(9):e1134-e1143. PMID: 32636322.
      Citations: 23     Fields:    Translation:HumansCells
    112. Beyer MMS, Lonnemann N, Remus A, Latz E, Heneka MT, Korte M. Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent. J Neurosci. 2020 07 08; 40(28):5480-5494. PMID: 32499379.
      Citations: 24     Fields:    Translation:Animals
    113. Heneka MT, Golenbock D, Latz E, Morgan D, Brown R. Immediate and long-term consequences of COVID-19 infections for the development of neurological disease. Alzheimers Res Ther. 2020 06 04; 12(1):69. PMID: 32498691.
      Citations: 207     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    114. Schr?der N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. J Neuroinflammation. 2020 Apr 24; 17(1):131. PMID: 32331524.
      Citations: 13     Fields:    Translation:Animals
    115. Villacampa N, Heneka MT. Microglia in Alzheimer's disease: Local heroes! J Exp Med. 2020 04 06; 217(4). PMID: 32126139.
      Citations: 6     Fields:    Translation:HumansCells
    116. McManus RM, Heneka MT. T cells in Alzheimer's disease: space invaders. Lancet Neurol. 2020 04; 19(4):285-287. PMID: 32199089.
      Citations: 7     Fields:    Translation:HumansCells
    117. Friker LL, Scheiblich H, Hochheiser IV, Brinkschulte R, Riedel D, Latz E, Geyer M, Heneka MT. ?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia. Cell Rep. 2020 03 17; 30(11):3743-3754.e6. PMID: 32187546.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    118. Kleineidam L, Chouraki V, Pr?chnicki T, van der Lee SJ, Madrid-M?rquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, Hulsman M, Kornhuber J, Peters O, Berr C, Heun R, Fr?lich L, Tzourio C, Dartigues JF, H?ll M, Espinosa A, Hern?ndez I, de Rojas I, Orellana A, Valero S, Stringa N, van Schoor NM, Huisman M, Scheltens P, R?ther E, Deleuze JF, Wiltfang J, Tarraga L, Schmid M, Scherer M, Riedel-Heller S, Heneka MT, Amouyel P, Jessen F, Boada M, Maier W, Schneider A, Gonz?lez-P?rez A, van der Flier WM, Wagner M, Lambert JC, Holstege H, S?ez ME, Latz E, Ruiz A, Ramirez A. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathol. 2020 06; 139(6):1025-1044. PMID: 32166339.
      Citations: 23     Fields:    Translation:Humans
    119. Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nat Rev Neurol. 2020 04; 16(4):193-197. PMID: 32152461.
      Citations: 54     Fields:    Translation:HumansCells
    120. Scheiblich H, Trombly M, Ramirez A, Heneka MT. Neuroimmune Connections in Aging and Neurodegenerative Diseases. Trends Immunol. 2020 04; 41(4):300-312. PMID: 32147113.
      Citations: 63     Fields:    Translation:Humans
    121. Luciunaite A, McManus RM, Jankunec M, R?cz I, Dansokho C, Dalgediene I, Schwartz S, Brosseron F, Heneka MT. Soluble A? oligomers and protofibrils induce NLRP3 inflammasome activation in microglia. J Neurochem. 2020 12; 155(6):650-661. PMID: 31872431.
      Citations: 55     Fields:    Translation:AnimalsCells
    122. Brosseron F, Kolbe CC, Santarelli F, Carvalho S, Antonell A, Castro-Gomez S, Tacik P, Namasivayam AA, Mangone G, Schneider R, Latz E, W?llner U, Svenningsson P, S?nchez-Valle R, Molinuevo JL, Corvol JC, Heneka MT. Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. Alzheimers Dement. 2020 02; 16(2):292-304. PMID: 31630996.
      Citations: 18     Fields:    Translation:Humans
    123. Heneka MT. An immune-cell signature marks the brain in Alzheimer's disease. Nature. 2020 01; 577(7790):322-323. PMID: 31937952.
      Citations: 7     Fields:    Translation:HumansCells
    124. Trasch?tz A, Enkirch SJ, Polomac N, Widmann CN, Schild HH, Heneka MT, Hattingen E. The Entorhinal Cortex Atrophy Score Is Diagnostic and Prognostic in Mild Cognitive Impairment. J Alzheimers Dis. 2020; 75(1):99-108. PMID: 32250289.
      Citations: 8     Fields:    Translation:Humans
    125. Riester K, Brawek B, Savitska D, Fr?hlich N, Zirdum E, Mojtahedi N, Heneka MT, Garaschuk O. In vivo characterization of functional states of cortical microglia during peripheral inflammation. Brain Behav Immun. 2020 07; 87:243-255. PMID: 31837418.
      Citations: 11     Fields:    Translation:HumansCells
    126. Mantile F, Capasso A, Villacampa N, Donnini M, Liguori GL, Constantin G, De Berardinis P, Heneka MT, Prisco A. Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice. Aging Clin Exp Res. 2021 May; 33(5):1383-1387. PMID: 31758499.
      Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    127. Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock DT, Blum D, Latz E, Bu?e L, Heneka MT. NLRP3 inflammasome activation drives tau pathology. Nature. 2019 11; 575(7784):669-673. PMID: 31748742.
      Citations: 459     Fields:    Translation:HumansAnimalsCells
    128. Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunol Cell Biol. 2020 01; 98(1):28-41. PMID: 31654430.
      Citations: 141     Fields:    Translation:HumansAnimalsCells
    129. Venegas C, Heneka MT. Inflammasome-mediated innate immunity in Alzheimer's disease. FASEB J. 2019 12; 33(12):13075-13084. PMID: 31702392.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    130. Mercan D, Heneka MT. Norepinephrine as a modulator of microglial dynamics. Nat Neurosci. 2019 11; 22(11):1745-1746. PMID: 31636450.
      Citations: 2     Fields:    Translation:AnimalsCells
    131. Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. J Neurochem. 2020 03; 152(6):710-726. PMID: 31520481.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    132. Berron D, Cardenas-Blanco A, Bittner D, Metzger CD, Spottke A, Heneka MT, Fliessbach K, Schneider A, Teipel SJ, Wagner M, Speck O, Jessen F, D?zel E. Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults. J Neurosci. 2019 10 30; 39(44):8788-8797. PMID: 31541019.
      Citations: 34     Fields:    Translation:Humans
    133. Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Fr?lich L, H?ll M, Wiltfang J, Scherer M, Riedel-Heller S, Schneider A, Heneka MT, Fliessbach K, Sharaf A, Thiele H, Lennarz M, Jessen F, Maier W, Kubisch C, Ignatova Z, N?rnberg P, Pastor P, Walter J, Ramirez A. A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Hum Mutat. 2020 01; 41(1):169-181. PMID: 31464095.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    134. Bainbridge WA, Berron D, Sch?tze H, Cardenas-Blanco A, Metzger C, Dobisch L, Bittner D, Glanz W, Spottke A, Rudolph J, Brosseron F, Buerger K, Janowitz D, Fliessbach K, Heneka M, Laske C, Buchmann M, Peters O, Diesing D, Li S, Priller J, Spruth EJ, Altenstein S, Schneider A, Kofler B, Teipel S, Kilimann I, Wiltfang J, Bartels C, Wolfsgruber S, Wagner M, Jessen F, Baker CI, D?zel E. Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment. Alzheimers Dement (Amst). 2019 Dec; 11:610-618. PMID: 31517023.
      Citations:    
    135. Castro-Gomez S, Binder J, Heneka MT. [Neuroinflammation as motor of Alzheimer's disease]. Nervenarzt. 2019 Sep; 90(9):898-906. PMID: 31428829.
      Citations: 5     Fields:    Translation:HumansCells
    136. Bertens D, Vos S, Kehoe P, Wolf H, Nobili F, Mendon?a A, van Rossum I, Hort J, Molinuevo JL, Heneka M, Petersen R, Scheltens P, Visser PJ. Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey. Alzheimers Res Ther. 2019 08 22; 11(1):74. PMID: 31439020.
      Citations: 13     Fields:    Translation:Humans
    137. Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, Laske C, Buchmann M, Schneider A, Fliessbach K, Kalbhen P, Heneka MT, Brosseron F, Spottke A, Roy N, Teipel SJ, Kilimann I, Wiltfang J, Bartels C, D?zel E, Dobisch L, Metzger C, Meiberth D, Ramirez A, Jessen F, Wagner M. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimers Res Ther. 2019 07 31; 11(1):66. PMID: 31366409.
      Citations: 38     Fields:    Translation:Humans
    138. Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome. EMBO J. 2019 09 02; 38(17):e101064. PMID: 31359456.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    139. Esteve P, Rueda-Carrasco J, In?s Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandon?s ?, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, R?bano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Dom?nguez M, Bovolenta P. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nat Neurosci. 2019 08; 22(8):1258-1268. PMID: 31308530.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    140. Nitsch L, Zimmermann J, Krauthausen M, Hofer MJ, Saggu R, Petzold GC, Heneka MT, Getts DR, Becker A, Campbell IL, M?ller M. CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model. Mol Neurobiol. 2019 Dec; 56(12):7977-7993. PMID: 31154574.
      Citations: 8     Fields:    Translation:AnimalsCells
    141. Franzmeier N, Ren J, Damm A, Mont?-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, D?zel E, Rodr?guez G?mez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Su?rez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M. The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Mol Psychiatry. 2021 02; 26(2):614-628. PMID: 30899092.
      Citations: 29     Fields:    Translation:Humans
    142. Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression. Mol Neurobiol. 2019 Sep; 56(9):6539-6550. PMID: 30852796.
      Citations: 16     Fields:    Translation:HumansCells
    143. Heneka MT, McManus RM, Latz E. Author Correction: Inflammasome signalling in brain function and neurodegenerative disease. Nat Rev Neurosci. 2019 Mar; 20(3):187. PMID: 30742056.
      Citations: 4     Fields:    
    144. Heneka MT. Microglia take centre stage in neurodegenerative disease. Nat Rev Immunol. 2019 02; 19(2):79-80. PMID: 30610221.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    145. Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padr?s N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, Spottke A, Heneka MT, D?zel E, Drzezga A, Wiltfang J, Sikkes SAM, van der Flier WM, Jessen F. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 01 17; 11(1):8. PMID: 30654834.
      Citations: 12     Fields:    Translation:Humans
    146. Tejera D, Heneka MT. Microglia in Neurodegenerative Disorders. Methods Mol Biol. 2019; 2034:57-67. PMID: 31392677.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    147. Tejera D, Heneka MT. In Vivo Phagocytosis Analysis of Amyloid Beta. Methods Mol Biol. 2019; 2034:287-292. PMID: 31392693.
      Citations: 7     Fields:    Translation:AnimalsCells
    148. Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Flie?bach K, Haynes JD, Heneka MT, Kilimann I, Laske C, Li S, Menne F, Metzger CD, Priller J, Pross V, Ramirez A, Scheffler K, Schneider A, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Wolfsgruber S, D?zel E, Jessen F, Dyrba M. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. J Alzheimers Dis. 2019; 72(2):455-465. PMID: 31594223.
      Citations: 6     Fields:    Translation:Humans
    149. D?zel E, Berron D, Sch?tze H, Cardenas-Blanco A, Metzger C, Betts M, Ziegler G, Chen Y, Dobisch L, Bittner D, Glanz W, Reuter M, Spottke A, Rudolph J, Brosseron F, Buerger K, Janowitz D, Fliessbach K, Heneka M, Laske C, Buchmann M, Nestor P, Peters O, Diesing D, Li S, Priller J, Spruth EJ, Altenstein S, Ramirez A, Schneider A, Kofler B, Speck O, Teipel S, Kilimann I, Dyrba M, Wiltfang J, Bartels C, Wolfsgruber S, Wagner M, Jessen F. CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimers Dement (Amst). 2018; 10:782-790. PMID: 30555890.
      Citations:    
    150. Hu X, Teunissen CE, Spottke A, Heneka MT, D?zel E, Peters O, Li S, Priller J, Buerger K, Teipel S, Laske C, Verfaillie SCJ, Barkhof F, Coll-Padr?s N, Rami L, Molinuevo JL, van der Flier WM, Jessen F. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimers Dement. 2019 02; 15(2):185-193. PMID: 30321506.
      Citations: 17     Fields:    Translation:Humans
    151. Heneka MT, McManus RM, Latz E. Inflammasome signalling in brain function and neurodegenerative disease. Nat Rev Neurosci. 2018 10; 19(10):610-621. PMID: 30206330.
      Citations: 278     Fields:    Translation:HumansAnimalsCells
    152. Trasch?tz A, Heneka MT. Screening for Niemann-Pick Type C Disease in a Memory Clinic Cohort. JIMD Rep. 2019; 44:109-114. PMID: 30187371.
      Citations:    
    153. Ativie F, Komorowska JA, Beins E, Albayram ?, Zimmer T, Zimmer A, Tejera D, Heneka M, Bilkei-Gorzo A. Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity. Front Mol Neurosci. 2018; 11:295. PMID: 30210289.
      Citations:    
    154. Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):9002-9007. PMID: 30127003.
      Citations: 26     Fields:    Translation:AnimalsCells
    155. Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J, Parsons CG. The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (A?) species on long-term potentiation (LTP). Neuropharmacology. 2018 09 15; 140:184-192. PMID: 30016667.
      Citations: 11     Fields:    Translation:AnimalsCells
    156. Faivre E, Coelho JE, Zornbach K, Malik E, Baqi Y, Schneider M, Cellai L, Carvalho K, Sebda S, Figeac M, Eddarkaoui S, Caillierez R, Chern Y, Heneka M, Sergeant N, M?ller CE, Halle A, Bu?e L, Lopes LV, Blum D. Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease. Front Mol Neurosci. 2018; 11:235. PMID: 30050407.
      Citations:    
    157. Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Wolleb?k Johannesen S, G?ricke B. Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial. Lancet Neurol. 2018 08; 17(8):681-688. PMID: 29934198.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    158. Lehmer C, Schludi MH, Ransom L, Greiling J, Jungh?nel M, Exner N, Riemenschneider H, van der Zee J, Van Broeckhoven C, Weydt P, Heneka MT, Edbauer D. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. EMBO Mol Med. 2018 06; 10(6). PMID: 29789341.
      Citations: 24     Fields:    Translation:HumansCells
    159. Kalinin S, Gonz?lez-Prieto M, Scheiblich H, Lisi L, Kusumo H, Heneka MT, Madrigal JLM, Pandey SC, Feinstein DL. Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. J Neuroinflammation. 2018 May 14; 15(1):141. PMID: 29759078.
      Citations: 20     Fields:    Translation:AnimalsCells
    160. Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Ro?ner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037. PMID: 29630865.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    161. Franzmeier N, D?zel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Su?rez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain. 2018 04 01; 141(4):1186-1200. PMID: 29462334.
      Citations: 50     Fields:    Translation:Humans
    162. Enkirch SJ, Trasch?tz A, M?ller A, Widmann CN, Gielen GH, Heneka MT, Jurcoane A, Schild HH, Hattingen E. The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease. Radiology. 2018 Jul; 288(1):226-333. PMID: 29514015.
      Citations: 16     Fields:    Translation:Humans
    163. Brosseron F, Trasch?tz A, Widmann CN, Kummer MP, Tacik P, Santarelli F, Jessen F, Heneka MT. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimers Res Ther. 2018 02 26; 10(1):25. PMID: 29482610.
      Citations: 42     Fields:    Translation:Humans
    164. Villacampa N, Heneka MT. Microglia: You'll Never Walk Alone! Immunity. 2018 02 20; 48(2):195-197. PMID: 29466750.
      Citations: 6     Fields:    Translation:HumansCells
    165. Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, Peters O, Priller J, Pross V, Ramirez A, Schneider A, Speck O, Spruth EJ, Teipel S, Vukovich R, Westerteicher C, Wiltfang J, Wolfsgruber S, Wagner M, D?zel E. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimers Res Ther. 2018 02 07; 10(1):15. PMID: 29415768.
      Citations: 68     Fields:    Translation:Humans
    166. Ising C, Heneka MT. Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration. Cell Death Dis. 2018 01 25; 9(2):120. PMID: 29371603.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    167. Teipel SJ, Metzger CD, Brosseron F, Buerger K, Brueggen K, Catak C, Diesing D, Dobisch L, Fliebach K, Franke C, Heneka MT, Kilimann I, Kofler B, Menne F, Peters O, Polcher A, Priller J, Schneider A, Spottke A, Spruth EJ, Thelen M, Thyrian RJ, Wagner M, D?zel E, Jessen F, Dyrba M. Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease. J Alzheimers Dis. 2018; 64(3):801-813. PMID: 29914027.
      Citations: 8     Fields:    Translation:Humans
    168. Dansokho C, Heneka MT. Neuroinflammatory responses in Alzheimer's disease. J Neural Transm (Vienna). 2018 05; 125(5):771-779. PMID: 29273951.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    169. Kaczmarczyk R, Tejera D, Simon BJ, Heneka MT. Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease. J Neurochem. 2017 Dec 21. PMID: 29266221.
      Citations: 45     Fields:    
    170. Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease. Nature. 2017 12 20; 552(7685):355-361. PMID: 29293211.
      Citations: 379     Fields:    Translation:HumansAnimalsCells
    171. Tejera D, Heneka MT. United Again: STING and the Police. Neuron. 2017 12 20; 96(6):1207-1208. PMID: 29268089.
      Citations:    Fields:    Translation:HumansAnimalsCells
    172. Ardura-Fabregat A, Boddeke EWGM, Boza-Serrano A, Brioschi S, Castro-Gomez S, Ceyz?riat K, Dansokho C, Dierkes T, Gelders G, Heneka MT, Hoeijmakers L, Hoffmann A, Iaccarino L, Jahnert S, Kuhbandner K, Landreth G, Lonnemann N, L?schmann PA, McManus RM, Paulus A, Reemst K, Sanchez-Caro JM, Tiberi A, Van der Perren A, Vautheny A, Venegas C, Webers A, Weydt P, Wijasa TS, Xiang X, Yang Y. Targeting Neuroinflammation to Treat Alzheimer's Disease. CNS Drugs. 2017 12; 31(12):1057-1082. PMID: 29260466.
      Citations: 95     Fields:    Translation:HumansAnimals
    173. Trasch?tz A, Kummer MP, Schwartz S, Heneka MT. Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice. Behav Processes. 2018 Dec; 157:711-716. PMID: 29155004.
      Citations: 7     Fields:    Translation:Animals
    174. Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annu Rev Med. 2018 01 29; 69:437-449. PMID: 29106805.
      Citations: 142     Fields:    Translation:HumansCells
    175. Scheiblich H, Schl?tter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Activation of the NLRP3 inflammasome in microglia: the role of ceramide. J Neurochem. 2017 12; 143(5):534-550. PMID: 28940479.
      Citations: 64     Fields:    Translation:AnimalsCells
    176. Sarlus H, Heneka MT. Microglia in Alzheimer's disease. J Clin Invest. 2017 Sep 01; 127(9):3240-3249. PMID: 28862638.
      Citations: 370     Fields:    Translation:HumansAnimalsCells
    177. M?ller S, Preische O, G?pfert JC, Ya?ez VAC, Joos TO, Boecker H, D?zel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, Peters O, Menne F, Schipke CG, Schneider A, Spottke A, Flie?bach K, Kilimann I, Teipel S, Wagner M, Wiltfang J, Jessen F, Laske C. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Sci Rep. 2017 08 25; 7(1):9529. PMID: 28842559.
      Citations: 16     Fields:    Translation:Humans
    178. Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Kummer MP, Brosseron F, Gieselmann V, Heneka MT. Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags. J Neurosci Methods. 2017 11 01; 291:95-100. PMID: 28789995.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    179. Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. A guiding map for inflammation. Nat Immunol. 2017 Jul 19; 18(8):826-831. PMID: 28722720.
      Citations: 260     Fields:    Translation:Humans
    180. Kemmerling N, Wunderlich P, Theil S, Linnartz-Gerlach B, Hersch N, Hoffmann B, Heneka MT, de Strooper B, Neumann H, Walter J. Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. Glia. 2017 07; 65(7):1103-1118. PMID: 28370426.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    181. Simchovitz A, Heneka MT, Soreq H. Personalized genetics of the cholinergic blockade of neuroinflammation. J Neurochem. 2017 08; 142 Suppl 2:178-187. PMID: 28326544.
      Citations: 18     Fields:    Translation:HumansAnimals
    182. McManus RM, Heneka MT. Role of neuroinflammation in neurodegeneration: new insights. Alzheimers Res Ther. 2017 Mar 04; 9(1):14. PMID: 28259169.
      Citations: 105     Fields:    Translation:Humans
    183. Heneka MT. Inflammasome activation and innate immunity in Alzheimer's disease. Brain Pathol. 2017 03; 27(2):220-222. PMID: 28019679.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    184. van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, B?umer V, Engelborghs S, De Bleecker J, Baets J, Gelpi E, Rojas-Garc?a R, Clarim?n J, Lle? A, Diehl-Schmid J, Alexopoulos P, Perneczky R, Synofzik M, Just J, Sch?ls L, Graff C, Thonberg H, Borroni B, Padovani A, Jordanova A, Sarafov S, Tournev I, de Mendon?a A, Miltenberger-Milt?nyi G, Sim?es do Couto F, Ramirez A, Jessen F, Heneka MT, G?mez-Tortosa E, Danek A, Cras P, Vandenberghe R, De Jonghe P, De Deyn PP, Sleegers K, Cruts M, Van Broeckhoven C, Goeman J, Nuytten D, Smets K, Robberecht W, Damme PV, Bleecker J, Santens P, Dermaut B, Versijpt J, Michotte A, Ivanoiu A, Deryck O, Bergmans B, Delbeck J, Bruyland M, Willems C, Salmon E, Pastor P, Ortega-Cubero S, Benussi L, Ghidoni R, Binetti G, Hern?ndez I, Boada M, Ruiz A, Sorbi S, Nacmias B, Bagnoli S, Sorbi S, Sanchez-Valle R, Llado A, Santana I, Ros?rio Almeida M, Frisoni GB, Maetzler W, Matej R, Fraidakis MJ, Kovacs GG, Fabrizi GM, Testi S. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Hum Mutat. 2017 03; 38(3):297-309. PMID: 28008748.
      Citations: 38     Fields:    Translation:HumansCells
    185. Zimmermann J, Emrich M, Krauthausen M, Saxe S, Nitsch L, Heneka MT, Campbell IL, M?ller M. IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination. Mol Neurobiol. 2018 02; 55(2):946-957. PMID: 28084589.
      Citations: 23     Fields:    Translation:AnimalsCells
    186. Venegas C, Heneka MT. Danger-associated molecular patterns in Alzheimer's disease. J Leukoc Biol. 2017 01; 101(1):87-98. PMID: 28049142.
      Citations: 85     Fields:    Translation:HumansAnimals
    187. Unger MS, Marschallinger J, Kaindl J, H?fling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease. Mol Neurobiol. 2016 10; 53(8):5796-806. PMID: 27544234.
      Citations: 40     Fields:    Translation:AnimalsCells
    188. Heneka MT, Nicotera P. Thoughts on Obesity and Brain Glucose. Cell. 2016 May 05; 165(4):773-5. PMID: 27153489.
      Citations: 4     Fields:    Translation:Humans
    189. Su?rez-Calvet M, Kleinberger G, Araque Caballero M?, Brendel M, Rominger A, Alcolea D, Fortea J, Lle? A, Blesa R, Gispert JD, S?nchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, Trasch?tz A, Heneka MT, Struyfs H, Engelborghs S, Sleegers K, Van Broeckhoven C, Zetterberg H, Nellg?rd B, Blennow K, Crispin A, Ewers M, Haass C. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. EMBO Mol Med. 2016 05; 8(5):466-76. PMID: 26941262.
      Citations: 221     Fields:    Translation:HumansCells
    190. Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Bj?rkhem I, Gustafsson J?, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, L?tjohann D, Latz E. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016 Apr 06; 8(333):333ra50. PMID: 27053774.
      Citations: 111     Fields:    Translation:HumansAnimalsCells
    191. Tejera D, Heneka MT. Microglia in Alzheimer's disease: the good, the bad and the ugly. Curr Alzheimer Res. 2016; 13(4):370-80. PMID: 26567746.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    192. Trasch?tz A, Tzaridis T, Penner AH, Kuchelmeister K, Urbach H, Hattingen E, Heneka MT. Reduction of microbleeds by immunosuppression in a patient with A?-related vascular inflammation. Neurol Neuroimmunol Neuroinflamm. 2015 Dec; 2(6):e165. PMID: 26516630.
      Citations: 4     Fields:    
    193. Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, M?ller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, M?ller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. ?-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015 Oct 15; 526(7573):443-7. PMID: 26322584.
      Citations: 170     Fields:    Translation:HumansAnimalsCells
    194. Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS One. 2015; 10(7):e0132227. PMID: 26168044.
      Citations: 16     Fields:    Translation:HumansAnimals
    195. Heneka MT, Fink A, Doblhammer G. Effect of pioglitazone medication on the incidence of dementia. Ann Neurol. 2015 Aug; 78(2):284-94. PMID: 25974006.
      Citations: 85     Fields:    Translation:Humans
    196. Heilmann S, Drichel D, Clarimon J, Fern?ndez V, Lacour A, Wagner H, Thelen M, Hern?ndez I, Fortea J, Alegret M, Blesa R, Maule?n A, Roca MR, Kornhuber J, Peters O, Heun R, Fr?lich L, H?ll M, Heneka MT, R?ther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, T?rraga L, Boada M, Maier W, Lle? A, Ruiz A, N?then MM, Ramirez A. PLD3 in non-familial Alzheimer's disease. Nature. 2015 Apr 02; 520(7545):E3-5. PMID: 25832411.
      Citations: 28     Fields:    Translation:Humans
    197. Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015 Apr; 14(4):388-405. PMID: 25792098.
      Citations: 2198     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    198. Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nat Immunol. 2015 Mar; 16(3):229-36. PMID: 25689443.
      Citations: 338     Fields:    Translation:HumansAnimals
    199. Kurzwelly D, Kr?ger S, Biskup S, Heneka MT. A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation. Brain. 2015 Sep; 138(Pt 9):e376. PMID: 25681414.
      Citations: 24     Fields:    Translation:HumansCells
    200. Meiberth D, Scheef L, Wolfsgruber S, Boecker H, Block W, Tr?ber F, Erk S, Heneka MT, Jacobi H, Spottke A, Walter H, Wagner M, Hu X, Jessen F. Cortical thinning in individuals with subjective memory impairment. J Alzheimers Dis. 2015; 45(1):139-46. PMID: 25471190.
      Citations: 34     Fields:    Translation:Humans
    201. Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, M?ller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015 Jan; 125(1):365-78. PMID: 25500888.
      Citations: 64     Fields:    Translation:AnimalsCells
    202. Widmann CN, Schewe JC, Heneka MT. Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply. Lancet Neurol. 2014 Oct; 13(10):968-9. PMID: 25231518.
      Citations: 6     Fields:    Translation:Humans
    203. Heneka MT. Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction. J Exp Med. 2014 Jul 28; 211(8):1500. PMID: 25071159.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    204. Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, Kornhuber J, Peters O, Naj AC, Chouraki V, Bellenguez C, Gerrish A, Heun R, Fr?lich L, H?ll M, Buscemi L, Herms S, K?lsch H, Scheltens P, Breteler MM, R?ther E, Wiltfang J, Goate A, Jessen F, Maier W, Heneka MT, Becker T, N?then MM. SUCLG2 identified as both a determinator of CSF A?1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Hum Mol Genet. 2014 Dec 15; 23(24):6644-58. PMID: 25027320.
      Citations: 27     Fields:    Translation:HumansCells
    205. Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de Le?n AR, de la Serna JP, Urcelay E, Kumar V, Franke L, Westra HJ, Drescher D, Kneist W, Marquardt JU, Galle PR, Mattheisen M, Annese V, Latiano A, Fumagalli U, Laghi L, Cuomo R, Sarnelli G, M?ller M, Eckardt AJ, Tack J, Hoffmann P, Herms S, Mangold E, Heilmann S, Kiesslich R, von Rahden BH, Allescher HD, Schulz HG, Wijmenga C, Heneka MT, Lang H, Hopfner KP, N?then MM, Boeckxstaens GE, de Bakker PI, Knapp M, Schumacher J. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nat Genet. 2014 Aug; 46(8):901-4. PMID: 24997987.
      Citations: 41     Fields:    Translation:Humans
    206. Kleinberger G, Yamanishi Y, Su?rez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lle? A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, S?nchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Sci Transl Med. 2014 Jul 02; 6(243):243ra86. PMID: 24990881.
      Citations: 342     Fields:    Translation:HumansCells
    207. Heneka MT, Kummer MP, Latz E. Innate immune activation in neurodegenerative disease. Nat Rev Immunol. 2014 Jul; 14(7):463-77. PMID: 24962261.
      Citations: 561     Fields:    Translation:HumansCells
    208. Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J Neurosci. 2014 Jun 25; 34(26):8845-54. PMID: 24966384.
      Citations: 36     Fields:    Translation:AnimalsCells
    209. Thelen M, Razquin C, Hern?ndez I, Gorostidi A, S?nchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Mart?nez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, H?ll M, R?ther E, Wiltfang J, Lorenzo E, Gascon J, Lle? A, Llad? A, Campdelacreu J, Moreno F, Ahmadzadehfar H, Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Fr?lich L, T?rraga L, Boada M, Wagner M, Jessen F, Maier W, Clarim?n J, L?pez de Munain A, Ruiz A, Pastor P, Ramirez A. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiol Aging. 2014 Nov; 35(11):2657.e13-2657.e19. PMID: 25042114.
      Citations: 14     Fields:    Translation:Humans
    210. Krauthausen M, Saxe S, Zimmermann J, Emrich M, Heneka MT, M?ller M. CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system. J Neuroinflammation. 2014 Jun 16; 11:109. PMID: 24930935.
      Citations: 17     Fields:    Translation:AnimalsCells
    211. van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Matej R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, Mattheijssens M, Peeters K, Benussi L, Binetti G, Ghidoni R, Borroni B, Padovani A, Archetti S, Pastor P, Razquin C, Ortega-Cubero S, Hern?ndez I, Boada M, Ruiz A, de Mendon?a A, Miltenberger-Milt?nyi G, do Couto FS, Sorbi S, Nacmias B, Bagnoli S, Graff C, Chiang HH, Thonberg H, Perneczky R, Diehl-Schmid J, Alexopoulos P, Frisoni GB, Bonvicini C, Synofzik M, Maetzler W, vom Hagen JM, Sch?ls L, Haack TB, Strom TM, Prokisch H, Dols-Icardo O, Clarim?n J, Lle? A, Santana I, Almeida MR, Santiago B, Heneka MT, Jessen F, Ramirez A, Sanchez-Valle R, Llado A, Gelpi E, Sarafov S, Tournev I, Jordanova A, Parobkova E, Fabrizi GM, Testi S, Salmon E, Str?bel T, Santens P, Robberecht W, De Jonghe P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Sleegers K, Van Broeckhoven C. Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration. Acta Neuropathol. 2014 Sep; 128(3):397-410. PMID: 24899140.
      Citations: 44     Fields:    Translation:HumansAnimals
    212. Widmann CN, Heneka MT. Long-term cerebral consequences of sepsis. Lancet Neurol. 2014 Jun; 13(6):630-6. PMID: 24849863.
      Citations: 145     Fields:    Translation:Humans
    213. Kummer MP, Heneka MT. Truncated and modified amyloid-beta species. Alzheimers Res Ther. 2014; 6(3):28. PMID: 25031638.
      Citations: 115     Fields:    
    214. Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Mol Neurobiol. 2015 Apr; 51(2):661-71. PMID: 24838579.
      Citations: 22     Fields:    Translation:AnimalsCells
    215. Brosseron F, Krauthausen M, Kummer M, Heneka MT. Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview. Mol Neurobiol. 2014 Oct; 50(2):534-44. PMID: 24567119.
      Citations: 185     Fields:    Translation:HumansAnimals
    216. Peter J, Scheef L, Abdulkadir A, Boecker H, Heneka M, Wagner M, Koppara A, Kl?ppel S, Jessen F. Gray matter atrophy pattern in elderly with subjective memory impairment. Alzheimers Dement. 2014 Jan; 10(1):99-108. PMID: 23867795.
      Citations: 63     Fields:    Translation:Humans
    217. Malhotra A, Younesi E, G?ndel M, M?ller B, Heneka MT, Hofmann-Apitius M. ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimers Dement. 2014 Mar; 10(2):238-46. PMID: 23830913.
      Citations: 33     Fields:    Translation:Humans
    218. Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimers Res Ther. 2013; 5(2):21. PMID: 23634965.
      Citations: 72     Fields:    
    219. Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, M?ller M. CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia. PLoS One. 2013; 8(2):e57307. PMID: 23468966.
      Citations: 35     Fields:    Translation:AnimalsCells
    220. Okroglic S, Widmann CN, Urbach H, Scheltens P, Heneka MT. Clinical symptoms and risk factors in cerebral microangiopathy patients. PLoS One. 2013; 8(2):e53455. PMID: 23393549.
      Citations: 22     Fields:    Translation:Humans
    221. van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, B?umer V, Maes G, Corsmit E, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Pimentel J, Nacmias B, Bagnoli S, Sorbi S, Graff C, Chiang HH, Westerlund M, Sanchez-Valle R, Llado A, Gelpi E, Santana I, Almeida MR, Santiago B, Frisoni G, Zanetti O, Bonvicini C, Synofzik M, Maetzler W, Vom Hagen JM, Sch?ls L, Heneka MT, Jessen F, Matej R, Parobkova E, Kovacs GG, Str?bel T, Sarafov S, Tournev I, Jordanova A, Danek A, Arzberger T, Fabrizi GM, Testi S, Salmon E, Santens P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Philtjens S, Sleegers K, B?umer V, Maes G, Corsmit E, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Philtjens S, Theuns J, Sleegers K, B?umer V, Maes G, Cruts M, Van Broeckhoven C, Engelborghs S, De Deyn PP, Cras P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenbulcke M, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Firmo C, Pimentel J, Sanchez-Valle R, Llado A, Antonell A, Molinuevo J, Gelpi E, Graff C, Chiang HH, Westerlund M, Graff C, Kinhult St?hlbom A, Thonberg H, Nennesmo I, B?rjesson-Hanson A, Nacmias B, Bagnoli S, Sorbi S, Bessi V, Piaceri I, Santana I, Santiago B, Santana I, Helena Ribeiro M, Ros?rio Almeida M, Oliveira C, Massano J, Garret C, Pires P, Frisoni G, Zanetti O, Bonvicini C, Sarafov S, Tournev I, Jordanova A, Tournev I, Kovacs GG, Str?bel T, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, Jessen F, Matej R, Parobkova E, Danel A, Arzberger T, Maria Fabrizi G, Testi S, Ferrari S, Cavallaro T, Salmon E, Santens P, Cras P. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Hum Mutat. 2013 Feb; 34(2):363-73. PMID: 23111906.
      Citations: 112     Fields:    Translation:HumansCells
    222. Molinuevo JL, Gispert JD, Dubois B, Heneka MT, Lleo A, Engelborghs S, Pujol J, de Souza LC, Alcolea D, Jessen F, Sarazin M, Lamari F, Balasa M, Antonell A, Rami L. The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study. J Alzheimers Dis. 2013; 36(1):67-77. PMID: 23524657.
      Citations: 22     Fields:    Translation:Humans
    223. Gaikwad SM, Heneka MT. Studying M1 and M2 states in adult microglia. Methods Mol Biol. 2013; 1041:185-97. PMID: 23813380.
      Citations: 13     Fields:    Translation:AnimalsCells
    224. Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 2013 Jan 31; 493(7434):674-8. PMID: 23254930.
      Citations: 1174     Fields:    Translation:HumansAnimals
    225. Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. J Neurosci. 2012 Dec 05; 32(49):17824-9. PMID: 23223301.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    226. Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012 Nov 28; 32(48):17321-31. PMID: 23197723.
      Citations: 171     Fields:    Translation:AnimalsCells
    227. Semmler A, Widmann CN, Okulla T, Urbach H, Kaiser M, Widman G, Mormann F, Weide J, Fliessbach K, Hoeft A, Jessen F, Putensen C, Heneka MT. Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors. J Neurol Neurosurg Psychiatry. 2013 Jan; 84(1):62-9. PMID: 23134661.
      Citations: 119     Fields:    Translation:Humans
    228. Scheef L, Spottke A, Daerr M, Joe A, Striepens N, K?lsch H, Popp J, Daamen M, Gorris D, Heneka MT, Boecker H, Biersack HJ, Maier W, Schild HH, Wagner M, Jessen F. Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment. Neurology. 2012 Sep 25; 79(13):1332-9. PMID: 22914828.
      Citations: 123     Fields:    Translation:Humans
    229. Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biol Psychiatry. 2013 Mar 01; 73(5):454-63. PMID: 22883210.
      Citations: 46     Fields:    Translation:AnimalsCells
    230. Semmler A, Okulla T, Kaiser M, Seifert B, Heneka MT. Long-term neuromuscular sequelae of critical illness. J Neurol. 2013 Jan; 260(1):151-7. PMID: 22820684.
      Citations: 18     Fields:    Translation:Humans
    231. Dupuis L, Dengler R, Heneka MT, Meyer T, Zierz S, Kassubek J, Fischer W, Steiner F, Lindauer E, Otto M, Dreyhaupt J, Grehl T, Hermann A, Winkler AS, Bogdahn U, Benecke R, Schrank B, Wessig C, Grosskreutz J, Ludolph AC. A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis. PLoS One. 2012; 7(6):e37885. PMID: 22715372.
      Citations: 63     Fields:    Translation:HumansAnimalsCTClinical Trials
    232. Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):351-4. PMID: 22651996.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    233. Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A. Glial cells in (patho)physiology. J Neurochem. 2012 Apr; 121(1):4-27. PMID: 22251135.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    234. Kummer MP, H?lsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. J Neuroimmune Pharmacol. 2012 Mar; 7(1):165-72. PMID: 22227962.
      Citations: 9     Fields:    Translation:Animals
    235. Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, R?be CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 01; 188(3):1098-107. PMID: 22198949.
      Citations: 202     Fields:    Translation:HumansAnimalsCells
    236. Heneka MT, Reyes-Irisarri E, H?ll M, Kummer MP. Impact and Therapeutic Potential of PPARs in Alzheimer's Disease. Curr Neuropharmacol. 2011 Dec; 9(4):643-50. PMID: 22654722.
      Citations: 46     Fields:    
    237. Krauthausen M, Ellis SL, Zimmermann J, Sarris M, Wakefield D, Heneka MT, Campbell IL, M?ller M. Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12. Am J Pathol. 2011 Nov; 179(5):2346-59. PMID: 21925471.
      Citations: 5     Fields:    Translation:AnimalsCells
    238. Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, K?nig S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation. Neuron. 2011 Sep 08; 71(5):833-44. PMID: 21903077.
      Citations: 147     Fields:    Translation:HumansAnimalsCells
    239. Mildner A, Schlevogt B, Kierdorf K, B?ttcher C, Erny D, Kummer MP, Quinn M, Br?ck W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011 Aug 03; 31(31):11159-71. PMID: 21813677.
      Citations: 178     Fields:    Translation:AnimalsCells
    240. Juckel G, Manitz MP, Br?ne M, Friebe A, Heneka MT, Wolf RJ. Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study. Schizophr Res. 2011 Sep; 131(1-3):96-100. PMID: 21752601.
      Citations: 67     Fields:    Translation:AnimalsCells
    241. Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, Llad? A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O'Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schr?der J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement. 2011 Jul; 7(4):386-395.e6. PMID: 21784349.
      Citations: 149     Fields:    Translation:HumansCells
    242. Terwel D, L?schmann YN, Schmidt HH, Sch?ler HR, Cantz T, Heneka MT. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease. J Neurochem. 2011 Jul; 118(1):105-12. PMID: 21517843.
      Citations: 23     Fields:    Translation:Animals
    243. Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson J?, Holtzman DM, Heneka MT. Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis. J Neurosci. 2011 May 11; 31(19):7049-59. PMID: 21562267.
      Citations: 105     Fields:    Translation:AnimalsCells
    244. Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, W?llner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J. 2011 Jun 01; 30(11):2255-65. PMID: 21527912.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    245. Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice. J Neurochem. 2011 Jan; 116(1):43-52. PMID: 21044080.
      Citations: 11     Fields:    Translation:Animals
    246. Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiol Aging. 2012 Feb; 33(2):426.e1-11. PMID: 21109328.
      Citations: 32     Fields:    Translation:Animals
    247. Fleisher-Berkovich S, Filipovich-Rimon T, Ben-Shmuel S, H?lsmann C, Kummer MP, Heneka MT. Distinct modulation of microglial amyloid ? phagocytosis and migration by neuropeptides (i). J Neuroinflammation. 2010 Oct 11; 7:61. PMID: 20937084.
      Citations: 34     Fields:    Translation:AnimalsCells
    248. Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, L?tjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. J Biol Chem. 2010 Nov 26; 285(48):37405-14. PMID: 20876579.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    249. Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. J Neural Transm (Vienna). 2010 Aug; 117(8):919-47. PMID: 20632195.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    250. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6058-63. PMID: 20231476.
      Citations: 207     Fields:    Translation:HumansAnimalsCells
    251. Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochem Int. 2010 Nov; 57(4):375-82. PMID: 20144675.
      Citations: 59     Fields:    Translation:Animals
    252. Schlachetzki JC, Fiebich BL, Haake E, de Oliveira AC, Candelario-Jalil E, Heneka MT, H?ll M. Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia. J Neuroinflammation. 2010 Jan 11; 7:2. PMID: 20064241.
      Citations: 25     Fields:    Translation:AnimalsCells
    253. J?ger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU. alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. J Neurochem. 2009 Dec; 111(6):1369-82. PMID: 19804379.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    254. Heneka MT, Rodr?guez JJ, Verkhratsky A. Neuroglia in neurodegeneration. Brain Res Rev. 2010 May; 63(1-2):189-211. PMID: 19944719.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    255. Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Sch?fers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. J Neurosci. 2009 Nov 11; 29(45):14177-84. PMID: 19906966.
      Citations: 64     Fields:    Translation:AnimalsCells
    256. Papi A, Tatenhorst L, Terwel D, Hermes M, Kummer MP, Orlandi M, Heneka MT. PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models. J Neurochem. 2009 Jun; 109(6):1779-90. PMID: 19457135.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    257. Heneka MT. Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients. Exp Neurol. 2009 Jun; 217(2):237-9. PMID: 19328200.
      Citations:    Fields:    Translation:HumansAnimalsCells
    258. Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, M?ller U, van Leuven F, L?tjohann D, Walter J. Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. J Neurosci. 2008 Nov 12; 28(46):12097-106. PMID: 19005074.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    259. Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Sch?fers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflammation. 2008 Sep 15; 5:38. PMID: 18793399.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    260. Landreth G, Jiang Q, Mandrekar S, Heneka M. PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics. 2008 Jul; 5(3):481-9. PMID: 18625459.
      Citations: 109     Fields:    Translation:HumansAnimals
    261. Kummer MP, Heneka MT. PPARs in Alzheimer's Disease. PPAR Res. 2008; 2008:403896. PMID: 18645613.
      Citations:    
    262. Tatenhorst L, Hahnen E, Heneka MT. Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors. PPAR Res. 2008; 2008:204514. PMID: 18725982.
      Citations:    
    263. Jiang Q, Heneka M, Landreth GE. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs. 2008; 22(1):1-14. PMID: 18072811.
      Citations: 74     Fields:    Translation:HumansAnimals
    264. Seufert S, Coras R, Tr?nkle C, Zlotos DP, Bl?mcke I, Tatenhorst L, Heneka MT, Hahnen E. PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion. PPAR Res. 2008; 2008:513943. PMID: 18815619.
      Citations:    
    265. Heneka MT, Landreth GE, H?ll M. Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders. Nat Clin Pract Neurol. 2007 Sep; 3(9):496-504. PMID: 17805244.
      Citations: 38     Fields:    Translation:HumansAnimals
    266. Winkeler A, Sena-Esteves M, Paulis LE, Li H, Waerzeggers Y, R?ckriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, Wienhard K, Heiss WD, Jacobs AH. Switching on the lights for gene therapy. PLoS One. 2007 Jun 13; 2(6):e528. PMID: 17565381.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    267. Heneka MT, Landreth GE. PPARs in the brain. Biochim Biophys Acta. 2007 Aug; 1771(8):1031-45. PMID: 17569578.
      Citations: 128     Fields:    Translation:HumansAnimals
    268. Kummer C, Winkeler A, Dittmar C, Bauer B, Rueger MA, Rueckriem B, Heneka MT, Vollmar S, Wienhard K, Fraefel C, Heiss WD, Jacobs AH. Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector. Mol Imaging. 2007 May-Jun; 6(3):181-92. PMID: 17532884.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    269. Jacobs AH, Rueger MA, Winkeler A, Li H, Vollmar S, Waerzeggers Y, Rueckriem B, Kummer C, Dittmar C, Klein M, Heneka MT, Herrlinger U, Fraefel C, Graf R, Wienhard K, Heiss WD. Imaging-guided gene therapy of experimental gliomas. Cancer Res. 2007 Feb 15; 67(4):1706-15. PMID: 17308112.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    270. Semmler A, Frisch C, Debeir T, Ramanathan M, Okulla T, Klockgether T, Heneka MT. Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model. Exp Neurol. 2007 Apr; 204(2):733-40. PMID: 17306796.
      Citations: 111     Fields:    Translation:AnimalsCells
    271. Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. J Neuroimmunol. 2007 Mar; 184(1-2):69-91. PMID: 17222916.
      Citations: 285     Fields:    Translation:HumansAnimalsCells
    272. Thees C, Kaiser M, Scholz M, Semmler A, Heneka MT, Baumgarten G, Hoeft A, Putensen C. Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome. Crit Care. 2007; 11(6):R123. PMID: 18045492.
      Citations: 11     Fields:    Translation:Humans
    273. Wahle T, Thal DR, Sastre M, Rentmeister A, Bogdanovic N, Famulok M, Heneka MT, Walter J. GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide. J Neurosci. 2006 Dec 06; 26(49):12838-46. PMID: 17151287.
      Citations: 46     Fields:    Translation:HumansCells
    274. Grommes C, Landreth GE, Sastre M, Beck M, Feinstein DL, Jacobs AH, Schlegel U, Heneka MT. Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment. Mol Pharmacol. 2006 Nov; 70(5):1524-33. PMID: 16887936.
      Citations: 37     Fields:    Translation:HumansAnimals
    275. Ambr?e O, Leimer U, Herring A, G?rtz N, Sachser N, Heneka MT, Paulus W, Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. Am J Pathol. 2006 Aug; 169(2):544-52. PMID: 16877355.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    276. Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14. PMID: 16837104.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    277. Sundararajan S, Jiang Q, Heneka M, Landreth G. PPARgamma as a therapeutic target in central nervous system diseases. Neurochem Int. 2006 Jul; 49(2):136-44. PMID: 16766086.
      Citations: 41     Fields:    Translation:HumansAnimals
    278. Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006 Apr-May; 24(2-3):167-76. PMID: 16472958.
      Citations: 173     Fields:    Translation:HumansAnimalsCells
    279. Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006 Feb 01; 26(5):1343-54. PMID: 16452658.
      Citations: 138     Fields:    Translation:AnimalsCells
    280. Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):443-8. PMID: 16407166.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    281. H?ll M, Berger M, Heneka M. Disease-modifying therapies in Alzheimer's disease: how far have we come? Drugs. 2006; 66(16):2075-93. PMID: 17112302.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    282. Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T, Heneka MT. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. J Immunol. 2005 Oct 15; 175(8):4948-55. PMID: 16210596.
      Citations: 46     Fields:    Translation:HumansCells
    283. Heneka MT, Sastre M, Dumitrescu-Ozimek L, Dewachter I, Walter J, Klockgether T, Van Leuven F. Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice. J Neuroinflammation. 2005 Oct 07; 2:22. PMID: 16212664.
      Citations: 142     Fields:    
    284. Semmler A, Okulla T, Sastre M, Dumitrescu-Ozimek L, Heneka MT. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. J Chem Neuroanat. 2005 Oct; 30(2-3):144-57. PMID: 16122904.
      Citations: 140     Fields:    Translation:AnimalsCells
    285. Sch?tz B, Reimann J, Dumitrescu-Ozimek L, Kappes-Horn K, Landreth GE, Sch?rmann B, Zimmer A, Heneka MT. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J Neurosci. 2005 Aug 24; 25(34):7805-12. PMID: 16120782.
      Citations: 100     Fields:    Translation:HumansAnimals
    286. Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide. J Biol Chem. 2005 Jul 29; 280(30):28110-7. PMID: 15923191.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    287. Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53. PMID: 15817521.
      Citations: 237     Fields:    Translation:AnimalsCells
    288. Grommes C, Landreth GE, Schlegel U, Heneka MT. The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells. J Pharmacol Exp Ther. 2005 May; 313(2):806-13. PMID: 15665144.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    289. Lacombe P, Mathews PM, Schmidt SD, Breidert T, Heneka MT, Landreth GE, Feinstein DL, Galea E. Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. J Neuroinflammation. 2004 Jul 02; 1(1):11. PMID: 15285804.
      Citations: 18     Fields:    
    290. Grommes C, Landreth GE, Heneka MT. Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. Lancet Oncol. 2004 Jul; 5(7):419-29. PMID: 15231248.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    291. Pershadsingh HA, Heneka MT, Saini R, Amin NM, Broeske DJ, Feinstein DL. Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. J Neuroinflammation. 2004 Apr 20; 1(1):3. PMID: 15285799.
      Citations: 29     Fields:    
    292. Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem. 2004 Jan; 88(2):494-501. PMID: 14690537.
      Citations: 138     Fields:    Translation:AnimalsCells
    293. Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. J Leukoc Biol. 2004 Mar; 75(3):478-85. PMID: 14657213.
      Citations: 31     Fields:    Translation:HumansCells
    294. Pedraza CE, Baltrons MA, Heneka MT, Garc?a A. Interleukin-1 beta and lipopolysaccharide decrease soluble guanylyl cyclase in brain cells: NO-independent destabilization of protein and NO-dependent decrease of mRNA. J Neuroimmunol. 2003 Nov; 144(1-2):80-90. PMID: 14597101.
      Citations: 9     Fields:    Translation:AnimalsCells
    295. Sastre M, Dewachter I, Landreth GE, Willson TM, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J Neurosci. 2003 Oct 29; 23(30):9796-804. PMID: 14586007.
      Citations: 143     Fields:    Translation:HumansAnimalsCells
    296. Galea E, Heneka MT, Dello Russo C, Feinstein DL. Intrinsic regulation of brain inflammatory responses. Cell Mol Neurobiol. 2003 Oct; 23(4-5):625-35. PMID: 14514020.
      Citations: 18     Fields:    Translation:HumansAnimals
    297. Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem. 2003 Aug; 86(4):907-16. PMID: 12887689.
      Citations: 13     Fields:    Translation:AnimalsCells
    298. Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. J Neurochem. 2003 Apr; 85(2):387-98. PMID: 12675915.
      Citations: 36     Fields:    Translation:Animals
    299. Harzheim M, Altenschmidt M, Heneka MT, Schr?der R, Klockgether T, Schmidt S. IFN-beta1a (Rebif) modifies the expression of microfilament-associated cell-cell contacts in C6 glioma cells. J Interferon Cytokine Res. 2003 Feb; 23(2):83-9. PMID: 12744773.
      Citations: 1     Fields:    Translation:HumansCells
    300. Feinstein DL, Heneka MT, Gavrilyuk V, Dello Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochem Int. 2002 Nov; 41(5):357-65. PMID: 12176079.
      Citations: 89     Fields:    Translation:HumansAnimals
    301. Baltrons MA, Pedraza CE, Heneka MT, Garc?a A. Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells. Neurobiol Dis. 2002 Jul; 10(2):139-49. PMID: 12127152.
      Citations: 15     Fields:    Translation:AnimalsCells
    302. Gavrilyuk V, Dello Russo C, Heneka MT, Pelligrino D, Weinberg G, Feinstein DL. Norepinephrine increases I kappa B alpha expression in astrocytes. J Biol Chem. 2002 Aug 16; 277(33):29662-8. PMID: 12050158.
      Citations: 23     Fields:    Translation:AnimalsCells
    303. Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G, Heneka MT. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Ann Neurol. 2002 Jun; 51(6):694-702. PMID: 12112074.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    304. Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. J Neurochem. 2002 Jun; 81(5):1052-60. PMID: 12065618.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    305. Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci. 2002 Apr 01; 22(7):2434-42. PMID: 11923407.
      Citations: 107     Fields:    Translation:AnimalsCells
    306. Murphy P, Sharp A, Shin J, Gavrilyuk V, Dello Russo C, Weinberg G, Sharp FR, Lu A, Heneka MT, Feinstein DL. Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. J Neurosci Res. 2002 Feb 15; 67(4):461-70. PMID: 11835313.
      Citations: 8     Fields:    Translation:AnimalsCells
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