P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.

Goel HL, Pursell B, Shultz LD, Greiner DL, Brekken RA, Vander Kooi CW, Mercurio AM. P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. Cell Rep. 2016 Mar 08; 14(9):2193-2208.

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subject areas

Adenocarcinoma
Angiogenesis Inhibitors
Animals
Bevacizumab
Carcinogenesis
Cell Line, Tumor
Cell Survival
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Guanine Nucleotide Exchange Factors
Humans
Indoles
Inhibitory Concentration 50
Male
Mice, Inbred NOD
Mice, SCID
Molecular Targeted Therapy
Neoplastic Stem Cells
Prostatic Neoplasms
Pyrroles
Receptors, Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor A
Xenograft Model Antitumor Assays

authors with profiles

Arthur M Mercurio PhD
Leonard Donald Shultz PhD
Hira Lal Goel PhD
Dale L Greiner PhD