Carcinogenesis

"Carcinogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Descriptor ID	D063646
MeSH Number(s)	C04.697.098 C23.550.727.098
Concept/Terms	Carcinogenesis Carcinogenesis Carcinogeneses Tumorigenesis Tumorigeneses Oncogenesis Oncogeneses

Below are MeSH descriptors whose meaning is more general than "Carcinogenesis".

Diseases [C]
Neoplasms [C04]
Neoplastic Processes [C04.697]
Carcinogenesis [C04.697.098]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Neoplastic Processes [C23.550.727]
Carcinogenesis [C23.550.727.098]

Below are MeSH descriptors whose meaning is related to "Carcinogenesis".

Below are MeSH descriptors whose meaning is more specific than "Carcinogenesis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carcinogenesis" by people in this website by year, and whether "Carcinogenesis" was a major or minor topic of these publications.

Bar chart showing 101 publications over 14 distinct years, with a maximum of 16 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2012	0	1	1
2013	0	2	2
2014	4	3	7
2015	4	6	10
2016	5	4	9
2017	6	5	11
2018	14	2	16
2019	6	6	12
2020	3	1	4
2021	5	3	8
2022	1	3	4
2023	0	4	4
2024	3	5	8
2025	4	1	5

Below are the most recent publications written about "Carcinogenesis" by people in Profiles.

Shin JH, Kim JY, Kim SH, Kang Y, Lee HJ, Kim MJ, Choi J, Jeong SK, Park SO, Cho YB, Kim KK, Shim JH, Chun E, Lee KY. USP11 promotes colorectal cancer progression by stabilizing EGFR and TRAF6: a potential therapeutic target in EGFR- and TLR-driven tumorigenesis. Cell Death Dis. 2025 Dec 19; 16(1):894.

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Clausen TM, Weiss RJ, Tremblay JR, Kellman BP, Coker J, Dworkin LA, Rodriguez JP, Chang IM, Chen T, Padala V, Karlsson R, Song H, Peck KL, Ogawa S, Sandoval DR, Joshi HJ, Wang G, Ferguson LP, Bhalerao N, Moores A, Reya T, Sander M, Caffrey TC, Grem JL, Aicher A, Heeschen C, Le D, Lewis NE, Hollingsworth MA, Grandgenett PM, Bellis SL, Miller RL, Fuster MM, Dawson DW, Engle DD, Esko JD. Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis. J Clin Invest. 2025 11 17; 135(22).

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Guo S, Hu X, Cotton JL, Ma L, Li Q, Cui J, Wang Y, Thakare RP, Tao Z, Ip YT, Wu X, Wang J, Mao J. VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300. Elife. 2025 May 08; 13.

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Wang W, Wang Y, Sanidad KZ, Wang Y, Zhang J, Yang W, Sun Q, Bayram I, Song R, Yang H, Johnson D, Sherman HL, Kim D, Minter LM, Wong JJ, Zeng MY, Decker EA, Zhang G. Oxidized Polyunsaturated Fatty Acid Promotes Colitis and Colitis-Associated Tumorigenesis in Mice. J Crohns Colitis. 2025 Mar 05; 19(3).

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Gaynor L, Singh H, Tie G, Badarinath K, Madha S, Mancini A, Bhattacharya S, Hoshino M, de Sauvage FJ, Murata K, Jadhav U, Shivdasani RA. Crypt density and recruited enhancers underlie intestinal tumour initiation. Nature. 2025 04; 640(8057):231-239.

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Gao Z, Zheng J, Wu X, Savinov S, Zhao C, Xiao H. Heat shock cognate 70 protein is a novel target of nobiletin and its colonic metabolites in inhibiting colon carcinogenesis. Food Funct. 2024 Oct 14; 15(20):10447-10458.

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Yang S, Humphries F. Emerging roles of ECSIT in immunity and tumorigenesis. Trends Cell Biol. 2025 May; 35(5):426-438.

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Su XA, Stopsack KH, Schmidt DR, Ma D, Li Z, Scheet PA, Penney KL, Lotan TL, Abida W, DeArment EG, Lu K, Janas T, Hu S, Vander Heiden MG, Loda M, Boselli M, Amon A, Mucci LA. RAD21 promotes oncogenesis and lethal progression of prostate cancer. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2405543121.

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Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Corr?a RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, R?sler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A, Yilmaz ?H. Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature. 2024 09; 633(8031):895-904.

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Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME. KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis. Cancer Res Commun. 2024 07 01; 4(7):1677-1689.

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