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A USP28-53BP1-p53-p21 signaling axis arrests growth after centrosome loss or prolonged mitosis.
Addressing families' unmet social needs within pediatric primary care: the health leads model.
Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung.
Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA.
Ligand-promoted protein folding by biased kinetic partitioning.
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Ligand-promoted protein folding by biased kinetic partitioning.
Hingorani KS, Metcalf MC, Deming DT, Garman SC, Powers ET, Gierasch LM. Ligand-promoted protein folding by biased kinetic partitioning. Nat Chem Biol. 2017 04; 13(4):369-371.
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subject areas
1-Deoxynojirimycin
alpha-Galactosidase
Escherichia coli
HEK293 Cells
Humans
Kinetics
Ligands
Models, Molecular
Molecular Chaperones
Protein Aggregates
Protein Folding
Proteolysis
Reproducibility of Results
Tetrahydrofolate Dehydrogenase
Trimethoprim
authors with profiles
Lila M Gierasch Ph.D.