"Uncoupling Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in heart and skeletal muscle tissues. It functions to regulate tissue respiration, energy balance, and THERMOGENESIS. Mutations in the UCP3 gene are associated with OBESITY.
| Descriptor ID |
D000071247
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| MeSH Number(s) |
D12.776.157.530.937.598.875 D12.776.543.585.475.688.875 D12.776.543.585.937.696.875 D12.776.575.750.688.875
|
| Concept/Terms |
Uncoupling Protein 3- Uncoupling Protein 3
- Uncoupling Protein-3
- Solute Carrier Family 25 Member 9
- UCP3 Protein
- SLC25A9 Protein
- Mitochondrial Uncoupling Protein 3
|
Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 3".
This graph shows the total number of publications written about "Uncoupling Protein 3" by people in this website by year, and whether "Uncoupling Protein 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Uncoupling Protein 3" by people in Profiles.
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Specht KS, Kant S, Addington AK, McMillan RP, Hulver MW, Learnard H, Campbell M, Donnelly SR, Caliz AD, Pei Y, Reif MM, Bond JM, DeMarco A, Craige B, Keaney JF, Craige SM. Nox4 mediates skeletal muscle metabolic responses to exercise. Mol Metab. 2021 03; 45:101160.
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Vieira E, Nilsson EC, Nerstedt A, Ormestad M, Long YC, Garcia-Roves PM, Zierath JR, Mahlapuu M. Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Nov; 295(5):E1032-7.
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Choi CS, Fillmore JJ, Kim JK, Liu ZX, Kim S, Collier EF, Kulkarni A, Distefano A, Hwang YJ, Kahn M, Chen Y, Yu C, Moore IK, Reznick RM, Higashimori T, Shulman GI. Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. J Clin Invest. 2007 Jul; 117(7):1995-2003.
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Fritz T, Kr?mer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev. 2006 Nov-Dec; 22(6):492-8.