Cancer-Associated Fibroblasts

"Cancer-Associated Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.

Descriptor ID	D000072645
MeSH Number(s)	A11.329.228.105
Concept/Terms	Cancer-Associated Fibroblasts Cancer-Associated Fibroblasts Cancer-Associated Fibroblast Fibroblast, Cancer-Associated Fibroblasts, Cancer-Associated Cancer Associated Fibroblasts Cancer Associated Fibroblast Fibroblast, Cancer Associated Fibroblasts, Cancer Associated Tumor-Associated Fibroblasts Fibroblast, Tumor-Associated Fibroblasts, Tumor-Associated Tumor Associated Fibroblasts Tumor-Associated Fibroblast

Below are MeSH descriptors whose meaning is more general than "Cancer-Associated Fibroblasts".

Anatomy [A]
Cells [A11]
Connective Tissue Cells [A11.329]
Fibroblasts [A11.329.228]
Cancer-Associated Fibroblasts [A11.329.228.105]

Below are MeSH descriptors whose meaning is related to "Cancer-Associated Fibroblasts".

Below are MeSH descriptors whose meaning is more specific than "Cancer-Associated Fibroblasts".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cancer-Associated Fibroblasts" by people in this website by year, and whether "Cancer-Associated Fibroblasts" was a major or minor topic of these publications.

Bar chart showing 3 publications over 2 distinct years, with a maximum of 2 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	0	1	1
2024	2	0	2

Below are the most recent publications written about "Cancer-Associated Fibroblasts" by people in Profiles.

Assouline B, Kahn R, Hodali L, Condiotti R, Engel Y, Elyada E, Mordechai-Heyn T, Pitarresi JR, Atias D, Steinberg E, Bidany-Mizrahi T, Forkosh E, Katz LH, Benny O, Golan T, Hofree M, Stewart SA, Atlan KA, Zamir G, Stanger BZ, Berger M, Ben-Porath I. Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice. Nat Commun. 2024 Jul 22; 15(1):6162.

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Murthy D, Attri KS, Shukla SK, Thakur R, Chaika NV, He C, Wang D, Jha K, Dasgupta A, King RJ, Mulder SE, Souchek J, Gebregiworgis T, Rai V, Patel R, Hu T, Rana S, Kollala SS, Pacheco C, Grandgenett PM, Yu F, Kumar V, Lazenby AJ, Black AR, Ulhannan S, Jain A, Edil BH, Klinkebiel DL, Powers R, Natarajan A, Hollingsworth MA, Mehla K, Ly Q, Chaudhary S, Hwang RF, Wellen KE, Singh PK. Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nat Cell Biol. 2024 04; 26(4):613-627.

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Elyada E, Bolisetty M, Laise P, Flynn WF, Courtois ET, Burkhart RA, Teinor JA, Belleau P, Biffi G, Lucito MS, Sivajothi S, Armstrong TD, Engle DD, Yu KH, Hao Y, Wolfgang CL, Park Y, Preall J, Jaffee EM, Califano A, Robson P, Tuveson DA. Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts. Cancer Discov. 2019 08; 9(8):1102-1123.

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Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D. Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metab. 2016 11 08; 24(5):685-700.

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