Header Logo

Simona Ceglia PhD

TitleInstructor
InstitutionUMass Chan Medical School
DepartmentPathology
AddressUMass Chan Medical School
368 Plantation Street, ASC
Worcester MA 01605
Phone508-856-7532
vCardDownload vCard
    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentPathology


    Collapse Biography 
    Collapse education and training
    Magna Graecia University, Catanzaro, , ItalyBS
    University of Insubria, Varese, VA, ItalyMS
    Magna Graecia University, Catanzaro, , ItalyDOCAMolecular Oncology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kellogg TD, Ceglia S, Mortzfeld BM, Tanna TM, Zeamer AL, Mancini MR, Foley SE, Ward DV, Bhattarai SK, McCormick BA, Reboldi A, Bucci V. Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile. J Exp Med. 2025 Jan 06; 222(1). PMID: 39589553.
      Citations:    
    2. Bettini E, Chudnovskiy A, Protti G, Nakadakari-Higa S, Ceglia S, Casta?o D, Chiu J, Muramatsu H, Mdluli T, Abraham E, Lipinszki Z, Maillard I, Tam YK, Reboldi A, Pardi N, Spreafico R, Victora GD, Locci M. Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses. bioRxiv. 2024 May 17. PMID: 38798523.
      Citations:    
    3. Kellogg TD, Ceglia S, Mortzfeld BM, Zeamer AL, Foley SE, Ward DV, Bhattarai SK, McCormick BA, Reboldi A, Bucci V. Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine. bioRxiv. 2024 Jan 31. PMID: 38352546.
      Citations:    
    4. Howley K, Berthelette A, Ceglia S, Kang J, Reboldi A. Embryonic type 3 innate lymphoid cells sense maternal dietary cholesterol to control local Peyer's patch development. bioRxiv. 2023 Mar 23. PMID: 36993524.
      Citations:    
    5. Ceglia S, Berthelette A, Howley K, Li Y, Mortzfeld B, Bhattarai SK, Yiew NKH, Xu Y, Brink R, Cyster JG, Hooper LV, Randolph GJ, Bucci V, Reboldi A. An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells. Nat Immunol. 2023 03; 24(3):531-544. PMID: 36658240.
      Citations: 9     Fields:    Translation:AnimalsCells
    6. Trindade BC, Ceglia S, Berthelette A, Raso F, Howley K, Muppidi JR, Reboldi A. The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation. Immunity. 2021 10 12; 54(10):2273-2287.e6. PMID: 34644558.
      Citations: 19     Fields:    Translation:AnimalsCells
    7. Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8. PMID: 34051146.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    8. Vecchio E, Golino G, Pisano A, Albano F, Falcone C, Ceglia S, Iaccino E, Mimmi S, Fiume G, Giurato G, Britti D, Scala G, Quinto I. IBTK contributes to B-cell lymphomagenesis in E?-myc transgenic mice conferring resistance to apoptosis. Cell Death Dis. 2019 04 11; 10(4):320. PMID: 30975981.
      Citations:    
    9. Iaccino E, Mimmi S, Dattilo V, Marino F, Candeloro P, Di Loria A, Marimpietri D, Pisano A, Albano F, Vecchio E, Ceglia S, Golino G, Lupia A, Fiume G, Quinto I, Scala G. Monitoring multiple myeloma by idiotype-specific peptide binders of tumor-derived exosomes. Mol Cancer. 2017 10 13; 16(1):159. PMID: 29029605.
      Citations:    
    10. Fiume G, Scialdone A, Rizzo F, De Filippo MR, Laudanna C, Albano F, Golino G, Vecchio E, Pontoriero M, Mimmi S, Ceglia S, Pisano A, Iaccino E, Palmieri C, Paduano S, Viglietto G, Weisz A, Scala G, Quinto I. IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells. Int J Mol Sci. 2016 Nov 07; 17(11). PMID: 27827994.
      Citations:    
    11. Fiume G, Scialdone A, Albano F, Rossi A, Tuccillo FM, Rea D, Palmieri C, Caiazzo E, Cicala C, Bellevicine C, Falcone C, Vecchio E, Pisano A, Ceglia S, Mimmi S, Iaccino E, de Laurentiis A, Pontoriero M, Agosti V, Troncone G, Mignogna C, Palma G, Arra C, Mallardo M, Buonaguro FM, Scala G, Quinto I. Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice. Sci Rep. 2015 Sep 07; 5:13864. PMID: 26343909.
      Citations:    
    12. Pisano A, Ceglia S, Palmieri C, Vecchio E, Fiume G, de Laurentiis A, Mimmi S, Falcone C, Iaccino E, Scialdone A, Pontoriero M, Masci FF, Valea R, Krishnan S, Gaspari M, Cuda G, Scala G, Quinto I. CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. J Biol Chem. 2015 May 29; 290(22):13958-71. PMID: 25882842.
      Citations:    
    13. Maestroni S, Maestroni A, Ceglia S, Tremolada G, Mancino M, Sacchi A, Lattanzio R, Zucchiatti I, Corti A, Bandello F, Zerbini G. Effect of chromogranin A-derived vasostatin-1 on laser-induced choroidal neovascularization in the mouse. Acta Ophthalmol. 2015 May; 93(3):e218-22. PMID: 25271003.
      Citations:    
    14. Serra R, Gallelli L, Conti A, De Caridi G, Massara M, Spinelli F, Buffone G, Cali? FG, Amato B, Ceglia S, Spaziano G, Scaramuzzino L, Ferrarese AG, Grande R, de Franciscis S. The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs. Drug Des Devel Ther. 2014; 8:519-27. PMID: 24872682.
      Citations:    
    Ceglia's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (129)
    Explore
    _
    Co-Authors (8)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _