The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway.
Heinen CD, Goss KH, Cornelius JR, Babcock GF, Knudsen ES, Kowalik T, Groden J. The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway. Gastroenterology. 2002 Sep; 123(3):751-63.