Transfection

"Transfection" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

Descriptor ID	D014162
MeSH Number(s)	E05.393.350.810 G05.728.860
Concept/Terms	Transfection Transfection Transfections

Below are MeSH descriptors whose meaning is more general than "Transfection".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Transfer Techniques [E05.393.350]
Transfection [E05.393.350.810]
Biological Sciences [G]
Genetic Phenomena [G05]
Recombination, Genetic [G05.728]
Transfection [G05.728.860]

Below are MeSH descriptors whose meaning is related to "Transfection".

Below are MeSH descriptors whose meaning is more specific than "Transfection".

Transfection
Transformation, Bacterial

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transfection" by people in this website by year, and whether "Transfection" was a major or minor topic of these publications.

Bar chart showing 527 publications over 30 distinct years, with a maximum of 42 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	3	20	23
1996	0	8	8
1997	1	10	11
1998	0	16	16
1999	0	15	15
2000	0	23	23
2001	0	27	27
2002	1	33	34
2003	1	41	42
2004	1	39	40
2005	2	32	34
2006	1	25	26
2007	1	21	22
2008	1	26	27
2009	0	26	26
2010	1	17	18
2011	1	21	22
2012	1	15	16
2013	1	8	9
2014	0	12	12
2015	0	16	16
2016	1	7	8
2017	2	16	18
2018	2	4	6
2019	2	6	8
2020	2	7	9
2021	0	4	4
2022	0	1	1
2024	0	3	3
2025	1	2	3

Below are the most recent publications written about "Transfection" by people in Profiles.

Liu H, Liu N, Zhou C, Du A, Kapadia M, Tai PWL, Barton E, Gao G, Wang D. High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling. EMBO Mol Med. 2025 Jun; 17(6):1475-1494.

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Green EA, Fu Q, Ndahiro N, Leibiger TM, Wang Y, Lee Y, Lee KH, Betenbaugh M, Yoon S, McNally DJ. Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing. Biotechnol Bioeng. 2025 Jul; 122(7):1640-1655.

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Wang Y, Fu Q, Sha S, Yoon S. Interferon inhibitors increase rAAV production in HEK293 cells. J Biotechnol. 2025 Mar; 399:9-18.

View in: PubMed
Fitzgerald K, Stephan SB, Ma N, Wu QV, Stephan MT. Liquid foam improves potency and safety of gene therapy vectors. Nat Commun. 2024 May 28; 15(1):4523.

View in: PubMed
Sun JW, Thomas JS, Monkovic JM, Gibson H, Nagapurkar A, Frezzo JA, Katyal P, Punia K, Mahmoudinobar F, Renfrew PD, Montclare JK. Supercharged coiled-coil protein with N-terminal decahistidine tag boosts siRNA complexation and delivery efficiency of a lipoproteoplex. J Pept Sci. 2024 Aug; 30(8):e3594.

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Wang Y, Fu Q, Park SY, Lee YS, Park SY, Lee DY, Yoon S. Decoding cellular mechanism of recombinant adeno-associated virus (rAAV) and engineering host-cell factories toward intensified viral vector manufacturing. Biotechnol Adv. 2024 Mar-Apr; 71:108322.

View in: PubMed
Zhou L, Emenuga M, Kumar S, Lamantia Z, Figueiredo M, Emrick T. Designing Synthetic Polymers for Nucleic Acid Complexation and Delivery: From Polyplexes to Micelleplexes to Triggered Degradation. Biomacromolecules. 2022 10 10; 23(10):4029-4040.

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Gopal S, Osborne AE, Hock L, Zemianek J, Fang K, Gee G, Ghosh R, McNally D, Cramer SM, Dordick JS. Advancing a rapid, high throughput screening platform for optimization of lentivirus production. Biotechnol J. 2021 Oct; 16(10):e2000621.

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Liu P, Liang SQ, Zheng C, Mintzer E, Zhao YG, Ponnienselvan K, Mir A, Sontheimer EJ, Gao G, Flotte TR, Wolfe SA, Xue W. Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. Nat Commun. 2021 04 09; 12(1):2121.

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Bao R, Surriga O, Olson DJ, Allred JB, Strand CA, Zha Y, Carll T, Labadie BW, Bastos BR, Butler M, Hogg D, Musi E, Ambrosini G, Munster P, Schwartz GK, Luke JJ. Transcriptional analysis of metastatic uveal melanoma survival nominates NRP1 as a therapeutic target. Melanoma Res. 2021 02 01; 31(1):27-37.

View in: PubMed

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