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Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
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Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Schrader CE, Linehan EK, Mochegova SN, Woodland RT, Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med. 2005 Aug 15; 202(4):561-8.
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PubMed
subject areas
Animals
B-Lymphocytes
Cytidine Deaminase
DNA
DNA Glycosylases
Gene Expression Regulation
Gene Rearrangement, B-Lymphocyte
Immunoglobulin Constant Regions
Immunoglobulin mu-Chains
Mice
Mice, Mutant Strains
Recombination, Genetic
Somatic Hypermutation, Immunoglobulin
Spleen
Uracil-DNA Glycosidase
authors with profiles
Janet Stavnezer PhD
Robert T Woodland PhD
Carol E Schrader PhD