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Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice.
Total hypotrichosis: genetic form of alopecia not linked to hairless gene.
Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.
Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF.
Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
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Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
Schrader CE, Linehan EK, Mochegova SN, Woodland RT, Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med. 2005 Aug 15; 202(4):561-8.
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PubMed
subject areas
Animals
B-Lymphocytes
Cytidine Deaminase
DNA
DNA Glycosylases
Gene Expression Regulation
Gene Rearrangement, B-Lymphocyte
Immunoglobulin Constant Regions
Immunoglobulin mu-Chains
Mice
Mice, Mutant Strains
Recombination, Genetic
Somatic Hypermutation, Immunoglobulin
Spleen
Uracil-DNA Glycosidase
authors with profiles
Janet Stavnezer PhD
Robert T Woodland PhD
Carol E Schrader PhD