Phosphorylation of Nur77 by the MEK-ERK-RSK cascade induces mitochondrial translocation and apoptosis in T cells.

Wang A, Rud J, Olson CM, Anguita J, Osborne BA. Phosphorylation of Nur77 by the MEK-ERK-RSK cascade induces mitochondrial translocation and apoptosis in T cells. J Immunol. 2009 Sep 1; 183(5):3268-77.

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subject areas

Active Transport, Cell Nucleus
Animals
Apoptosis
Cell Line
Cells, Cultured
DNA-Binding Proteins
Extracellular Signal-Regulated MAP Kinases
Humans
Intracellular Fluid
MAP Kinase Kinase Kinases
MAP Kinase Signaling System
Mice
Mice, Transgenic
Mitochondria
Nuclear Receptor Subfamily 4, Group A, Member 1
Phosphorylation
Protein Transport
Receptors, Steroid
Ribosomal Protein S6 Kinases
T-Lymphocytes

authors with profiles

Barbara A Osborne PhD