Mutations in bone marrow-derived stromal stem cells unmask latent malignancy.
Houghton J, Li H, Fan X, Liu Y, Liu JH, Rao VP, Poutahidis T, Taylor CL, Jackson EA, Hewes C, Lyle S, Cerny A, Bowen G, Cerny J, Moore N, Kurt-Jones EA, Erdman SE. Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev. 2010 Aug; 19(8):1153-66.
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Adult
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Aged
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Aged, 80 and over
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Animals
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Antigens, CD
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Bone Marrow
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Bone Marrow Cells
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Breast Neoplasms
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Carcinoma, Ductal, Breast
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Cell Line, Tumor
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Cell Movement
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Cell Proliferation
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Culture Media, Conditioned
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DNA-Binding Proteins
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Epithelium
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Female
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Fibroblasts
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Genes, APC
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Humans
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Mammary Glands, Animal
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Mammary Neoplasms, Animal
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Mesenchymal Stem Cell Transplantation
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Mice
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Mice, Inbred C57BL
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Mice, Inbred NOD
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Mice, Knockout
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Mice, Mutant Strains
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Mice, SCID
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Middle Aged
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Mutation
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Mutation, Missense
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Neoplasm Transplantation
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Stromal Cells
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T-Lymphocytes, Regulatory
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Transplantation, Heterologous
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Tumor Necrosis Factor-alpha
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Tumor Suppressor Protein p53