RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG, Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2783-8.
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Antibodies, Monoclonal
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Blotting, Northern
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Blotting, Western
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Cell Line
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Electrophoresis, Polyacrylamide Gel
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Electroporation
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Genetic Vectors
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Hepatitis C
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Humans
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Liver
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Models, Genetic
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Mutation
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Plasmids
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RNA
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RNA Interference
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RNA, Messenger
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RNA, Small Interfering
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RNA, Viral
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Time Factors
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Transcription, Genetic
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Transfection
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Tumor Cells, Cultured
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Virus Replication