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Rapid destruction of encapsulated islet xenografts by NOD mice is CD4-dependent and facilitated by B-cells: innate immunity and autoimmunity do not play significant roles.
Invasion of the killer B's in type 1 diabetes.
Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study.
Humanized mice for the study of type 1 diabetes and beta cell function.
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Humanized mice for the study of type 1 diabetes and beta cell function.
King M, Pearson T, Rossini AA, Shultz LD, Greiner DL. Humanized mice for the study of type 1 diabetes and beta cell function. Ann N Y Acad Sci. 2008 Dec; 1150:46-53.
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PubMed
subject areas
Animals
Autoimmunity
Diabetes Mellitus, Type 1
Disease Models, Animal
Humans
Immune System
Insulin-Secreting Cells
Mice
Mice, SCID
Stem Cells
Transplantation, Heterologous
authors with profiles
Dale L Greiner PhD
Leonard Donald Shultz PhD