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beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function.
Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.
Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
Humanized mice for the study of type 1 diabetes and beta cell function.
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Humanized mice for the study of type 1 diabetes and beta cell function.
King M, Pearson T, Rossini AA, Shultz LD, Greiner DL. Humanized mice for the study of type 1 diabetes and beta cell function. Ann N Y Acad Sci. 2008 Dec; 1150:46-53.
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PubMed
subject areas
Animals
Autoimmunity
Diabetes Mellitus, Type 1
Disease Models, Animal
Humans
Immune System
Insulin-Secreting Cells
Mice
Mice, SCID
Stem Cells
Transplantation, Heterologous
authors with profiles
Dale L Greiner PhD
Leonard Donald Shultz PhD