"Mutagens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
| Descriptor ID |
D009153
|
| MeSH Number(s) |
D27.888.569.468
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mutagens".
Below are MeSH descriptors whose meaning is more specific than "Mutagens".
This graph shows the total number of publications written about "Mutagens" by people in this website by year, and whether "Mutagens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Mutagens" by people in Profiles.
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Kim J, Huang AY, Johnson SL, Lai J, Isacco L, Jeffries AM, Miller MB, Lodato MA, Walsh CA, Lee EA. Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders. Nat Commun. 2022 10 07; 13(1):5918.
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Kordon MM, Arron S, Cleaver JE, Bezrookove V, Karentz D, Lu B, Perr E, Chang D, Pederson T. The UVSSA protein is part of a genome integrity homeostasis network with links to transcription-coupled DNA repair and ATM signaling. Proc Natl Acad Sci U S A. 2022 03 15; 119(11):e2116254119.
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Qin T, Zhang Y, Zarins KR, Jones TR, Virani S, Peterson LA, McHugh JB, Chepeha D, Wolf GT, Rozek LS, Sartor MA. Expressed HNSCC variants by HPV-status in a well-characterized Michigan cohort. Sci Rep. 2018 07 30; 8(1):11458.
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Malonia SK, Dutta P, Santra MK, Green MR. F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stress. Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28):8632-7.
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Calabrese EJ, Stanek EJ, Nascarella MA. A detailed re-assessment supports the conclusion of the paper that hormesis is commonly observed in the Ames assay. Mutat Res. 2012 Aug 30; 747(1):157.
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Calabrese EJ, Stanek EJ, Nascarella MA. Evidence for hormesis in mutagenicity dose-response relationships. Mutat Res. 2011 Dec 24; 726(2):91-7.
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Osowski A, Pietrzak M, Wieczorek Z, Wieczorek J. Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation. J Toxicol Environ Health A. 2010; 73(17-18):1141-9.
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Ravi D, Wiles AM, Bhavani S, Ruan J, Leder P, Bishop AJ. A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet. 2009 Jun; 5(6):e1000527.
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Pietrzak M, Halicka HD, Wieczorek Z, Wieczorek J, Darzynkiewicz Z. Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin. Biophys Chem. 2008 Jun; 135(1-3):69-75.
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Emery P. Mutagenesis with Drosophila. Methods Mol Biol. 2007; 362:187-95.