"Leukotriene C4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D017997
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| MeSH Number(s) |
D10.251.355.255.100.450.855.455 D10.251.355.310.166.887.855.455 D23.469.050.175.450.725.400
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Leukotriene C4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene C4".
This graph shows the total number of publications written about "Leukotriene C4" by people in this website by year, and whether "Leukotriene C4" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukotriene C4" by people in Profiles.
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Zhang X, Gonz?lez-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M. Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels. Mol Cell Biol. 2013 Sep; 33(18):3715-23.
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Gonz?lez-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, Trebak M. Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia. Circ Res. 2013 Mar 29; 112(7):1013-25.
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Seres I, F?ris G, Varga Z, Koszt?czky B, Kassai A, Balogh Z, F?l?p P, Paragh G. The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome. J Membr Biol. 2006; 214(2):91-8.
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Kalayci O, Birben E, Sackesen C, Keskin O, Tahan F, Wechsler ME, Civelek E, Soyer OU, Adalioglu G, Tuncer A, Israel E, Lilly C. ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. Allergy. 2006 Jan; 61(1):97-103.
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Strait RT, Morris SC, Smiley K, Urban JF, Finkelman FD. IL-4 exacerbates anaphylaxis. J Immunol. 2003 Apr 01; 170(7):3835-42.
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Kalayci O, Wechsler M, Galper B, Hong C, Israel E, Drazen JM, Lilly CM. LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter. Adv Exp Med Biol. 2003; 525:11-4.