Receptors, Cholinergic

"Receptors, Cholinergic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.

Descriptor ID	D011950
MeSH Number(s)	D12.776.543.750.720.360
Concept/Terms	Receptors, Cholinergic Receptors, Cholinergic Receptors, Acetylcholine Cholinoceptive Sites Sites, Cholinoceptive Receptors, ACh Cholinergic Receptors ACh Receptors Acetylcholine Receptors Cholinoceptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Cholinergic".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Cholinergic [D12.776.543.750.720.360]

Below are MeSH descriptors whose meaning is related to "Receptors, Cholinergic".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Cholinergic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Cholinergic" by people in this website by year, and whether "Receptors, Cholinergic" was a major or minor topic of these publications.

Bar chart showing 15 publications over 13 distinct years, with a maximum of 2 publications in 2004 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2004	0	2	2
2005	1	0	1
2006	1	0	1
2007	0	1	1
2010	0	1	1
2012	1	0	1
2013	1	0	1
2015	0	1	1
2017	2	0	2
2018	0	1	1
2023	0	1	1
2026	0	1	1

Below are the most recent publications written about "Receptors, Cholinergic" by people in Profiles.

Oliver DB, Ramachandran S, Biswas K, B?nard CY, Doitsidou M, McKillop H, Genao N, Lemons ML, Francis MM. Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons. G3 (Bethesda). 2026 04 01; 16(4).

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Cocanougher BT, Liu SW, Francescatto L, Behura A, Anneling M, Jackson DG, Deak KL, Hornik CD, ElMallah MK, Pizoli CE, Smith EC, Tan KGQ, McDonald MT. The severity of MUSK pathogenic variants is predicted by the protein domain they disrupt. HGG Adv. 2024 Jul 18; 5(3):100288.

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Alexander KD, Ramachandran S, Biswas K, Lambert CM, Russell J, Oliver DB, Armstrong W, Rettler M, Liu S, Doitsidou M, B?nard C, Walker AK, Francis MM. The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling. Nat Commun. 2023 11 18; 14(1):7520.

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Philbrook A, Ramachandran S, Lambert CM, Oliver D, Florman J, Alkema MJ, Lemons M, Francis MM. Neurexin directs partner-specific synaptic connectivity in C. elegans. Elife. 2018 07 24; 7.

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Schacht S, Masood F, Catmull S, Dolan R, Altabtabaee R, Grow W, Al-Nakkash L. Dietary Genistein Influences Number of Acetylcholine Receptors in Female Diabetic Jejunum. J Diabetes Res. 2017; 2017:3568146.

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Mott M, Luna VM, Park JY, Downes GB, Epley K, Ono F. Expressing acetylcholine receptors after innervation suppresses spontaneous vesicle release and causes muscle fatigue. Sci Rep. 2017 05 10; 7(1):1674.

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He S, Philbrook A, McWhirter R, Gabel CV, Taub DG, Carter MH, Hanna IM, Francis MM, Miller DM. Transcriptional Control of Synaptic Remodeling through Regulated Expression of an Immunoglobulin Superfamily Protein. Curr Biol. 2015 Oct 05; 25(19):2541-8.

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Petrash HA, Philbrook A, Haburcak M, Barbagallo B, Francis MM. ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans. J Neurosci. 2013 Mar 27; 33(13):5524-32.

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Jensen M, Hoerndli FJ, Brockie PJ, Wang R, Johnson E, Maxfield D, Francis MM, Madsen DM, Maricq AV. Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system. Cell. 2012 Mar 30; 149(1):173-87.

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Coyle JT, Balu D, Benneyworth M, Basu A, Roseman A. Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. Dialogues Clin Neurosci. 2010; 12(3):359-82.

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