"Hemoglobin, Sickle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
| Descriptor ID |
D006451
|
| MeSH Number(s) |
D12.776.124.400.463.588 D12.776.422.316.762.426.588
|
| Concept/Terms |
Deoxyhemoglobin S- Deoxyhemoglobin S
- Deoxygenated Sickle Hemoglobin
- Hemoglobin, Deoxygenated Sickle
- Sickle Hemoglobin, Deoxygenated
|
Below are MeSH descriptors whose meaning is more general than "Hemoglobin, Sickle".
Below are MeSH descriptors whose meaning is more specific than "Hemoglobin, Sickle".
This graph shows the total number of publications written about "Hemoglobin, Sickle" by people in this website by year, and whether "Hemoglobin, Sickle" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hemoglobin, Sickle" by people in Profiles.
-
St Louis J, Valdini A. Abnormally Low Hemoglobin A1c as Harbinger of Hemoglobinopathy. J Am Board Fam Med. 2019 Nov-Dec; 32(6):923-924.
-
Biller E, Zhao Y, Berg M, Boggio L, Capocelli KE, Fang DC, Koepsell S, Music-Aplenc L, Pham HP, Treml A, Weiss J, Wool G, Baron BW. Red blood cell exchange in patients with sickle cell disease-indications and management: a review and consensus report by the therapeutic apheresis subsection of the AABB. Transfusion. 2018 08; 58(8):1965-1972.
-
Moormann AM, Sumba PO, Chelimo K, Fang H, Tisch DJ, Dent AE, John CC, Long CA, Vulule J, Kazura JW. Humoral and cellular immunity to Plasmodium falciparum merozoite surface protein 1 and protection from infection with blood-stage parasites. J Infect Dis. 2013 Jul; 208(1):149-58.
-
Ghansah A, Rockett KA, Clark TG, Wilson MD, Koram KA, Oduro AR, Amenga-Etego L, Anyorigiya T, Hodgson A, Milligan P, Rogers WO, Kwiatkowski DP. Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana. PLoS One. 2012; 7(4):e34565.
-
Moormann AM, Embury PE, Opondo J, Sumba OP, Ouma JH, Kazura JW, John CC. Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya. Trans R Soc Trop Med Hyg. 2003 Sep-Oct; 97(5):513-4.
-
Harrington DJ, Adachi K, Royer WE. Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber. J Biol Chem. 1998 Dec 04; 273(49):32690-6.
-
Harrington DJ, Adachi K, Royer WE. The high resolution crystal structure of deoxyhemoglobin S. J Mol Biol. 1997 Sep 26; 272(3):398-407.