Chromosome Inversion

"Chromosome Inversion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome.

Descriptor ID	D007446
MeSH Number(s)	C23.550.210.190 G05.365.590.175.190 G05.365.590.770.500 G05.558.805.500
Concept/Terms	Chromosome Inversion Chromosome Inversion Chromosome Inversions Inversions, Chromosome Inversion, Chromosome Inversion, Chromosomal Chromosomal Inversion Chromosomal Inversions Inversions, Chromosomal

Below are MeSH descriptors whose meaning is more general than "Chromosome Inversion".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Chromosome Aberrations [C23.550.210]
Chromosome Inversion [C23.550.210.190]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]
Chromosome Aberrations [G05.365.590.175]
Chromosome Inversion [G05.365.590.175.190]
Sequence Inversion [G05.365.590.770]
Chromosome Inversion [G05.365.590.770.500]
Mutagenesis [G05.558]
Sequence Inversion [G05.558.805]
Chromosome Inversion [G05.558.805.500]

Below are MeSH descriptors whose meaning is related to "Chromosome Inversion".

Below are MeSH descriptors whose meaning is more specific than "Chromosome Inversion".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chromosome Inversion" by people in this website by year, and whether "Chromosome Inversion" was a major or minor topic of these publications.

Bar chart showing 8 publications over 8 distinct years, with a maximum of 1 publications in 1996 and 2002 and 2006 and 2008 and 2013 and 2015 and 2018 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2002	1	0	1
2006	0	1	1
2008	1	0	1
2013	1	0	1
2015	0	1	1
2018	0	1	1
2024	1	0	1

Below are the most recent publications written about "Chromosome Inversion" by people in Profiles.

Hegde M, Ahmad MH, Mulet Lazaro R, Sugita M, Li R, Hu K, Gebhard C, Guzman ML, Bushweller JH, Zhu LJ, Brehm M, Wolfe SA, Delwel R, Castilla LH. The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling. Leukemia. 2025 Feb; 39(2):360-370.

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Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH. CBF?-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. Cell. 2018 06 28; 174(1):172-186.e21.

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Li Y, Park AI, Mou H, Colpan C, Bizhanova A, Akama-Garren E, Joshi N, Hendrickson EA, Feldser D, Yin H, Anderson DG, Jacks T, Weng Z, Xue W. A versatile reporter system for CRISPR-mediated chromosomal rearrangements. Genome Biol. 2015 May 28; 16:111.

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Gupta A, Hall VL, Kok FO, Shin M, McNulty JC, Lawson ND, Wolfe SA. Targeted chromosomal deletions and inversions in zebrafish. Genome Res. 2013 Jun; 23(6):1008-17.

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Webb A, Miller B, Bonasera S, Boxer A, Karydas A, Wilhelmsen KC. Role of the tau gene region chromosome inversion in progressive supranuclear palsy, corticobasal degeneration, and related disorders. Arch Neurol. 2008 Nov; 65(11):1473-8.

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Heilman SA, Kuo YH, Goudswaard CS, Valk PJ, Castilla LH. Cbfbeta reduces Cbfbeta-SMMHC-associated acute myeloid leukemia in mice. Cancer Res. 2006 Dec 01; 66(23):11214-8.

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Siddiqui AD, Sheikh ZS, Liu D, Seiter K. Coexistence of inversion 16 and the Philadelphia chromosome in patients with acute myelogenous leukemia. Leuk Lymphoma. 2002 May; 43(5):1137-40.

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Martinez R, Sarisky RT, Weber PC, Weller SK. Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates. J Virol. 1996 Apr; 70(4):2075-85.

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Olds-Clarke P, Pilder SH, Visconti PE, Moss SB, Orth JM, Kopf GS. Sperm from mice carrying two t haplotypes do not possess a tyrosine phosphorylated form of hexokinase. Mol Reprod Dev. 1996 Jan; 43(1):94-104.

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Sarisky RT, Weber PC. Requirement for double-strand breaks but not for specific DNA sequences in herpes simplex virus type 1 genome isomerization events. J Virol. 1994 Jan; 68(1):34-47.

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