Excitatory Amino Acid Antagonists
"Excitatory Amino Acid Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
| Descriptor ID |
D018691
|
| MeSH Number(s) |
D27.505.519.625.190.300 D27.505.696.577.190.300
|
| Concept/Terms |
Excitatory Amino Acid Antagonists- Excitatory Amino Acid Antagonists
- Antagonists, Excitatory Amino Acid
- Amino Acids, Excitatory, Antagonists
- Glutamate Receptor Antagonists
- Antagonists, Glutamate Receptor
- Receptor Antagonists, Glutamate
- EAA Antagonists
- Antagonists, EAA
- Glutamate Antagonists
- Antagonists, Glutamate
- Amino Acid Antagonists, Excitatory
|
Below are MeSH descriptors whose meaning is more general than "Excitatory Amino Acid Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Excitatory Amino Acid Antagonists".
This graph shows the total number of publications written about "Excitatory Amino Acid Antagonists" by people in this website by year, and whether "Excitatory Amino Acid Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 2 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 2 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Excitatory Amino Acid Antagonists" by people in Profiles.
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Chen BK, Hunsberger HC, Whye A, Matthews LC, Yook A, Willner MJ, Logan RW, Johns S, Weisblum E, Denny CA. Combinatorial targeting of NMDARs and 5-HT4Rs exerts beneficial effects in a mouse model of Alzheimer's disease. Alzheimers Res Ther. 2025 07 15; 17(1):160.
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Sahib AK, Loureiro JRA, Vasavada MM, Kubicki A, Joshi SH, Wang K, Woods RP, Congdon E, Wang DJJ, Boucher ML, Espinoza R, Narr KL. Single and repeated ketamine treatment induces perfusion changes in sensory and limbic networks in major depressive disorder. Eur Neuropsychopharmacol. 2020 04; 33:89-100.
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Joffe ME, Santiago CI, Oliver KH, Maksymetz J, Harris NA, Engers JL, Lindsley CW, Winder DG, Conn PJ. mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects. Neuron. 2020 01 08; 105(1):46-59.e3.
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Snyder AE, Salimando GJ, Winder DG, Silberman Y. Chronic Intermittent Ethanol and Acute Stress Similarly Modulate BNST CRF Neuron Activity via Noradrenergic Signaling. Alcohol Clin Exp Res. 2019 08; 43(8):1695-1701.
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Holleran KM, Wilson HH, Fetterly TL, Bluett RJ, Centanni SW, Gilfarb RA, Rocco LE, Patel S, Winder DG. Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking. Neuropsychopharmacology. 2016 07; 41(8):2062-71.
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Haj-Mirzaian A, Kordjazy N, Haj-Mirzaian A, Ostadhadi S, Ghasemi M, Amiri S, Faizi M, Dehpour A. Evidence for the involvement of NMDA receptors in the antidepressant-like effect of nicotine in mouse forced swimming and tail suspension tests. Psychopharmacology (Berl). 2015 Oct; 232(19):3551-61.
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Ghasemi M, Phillips C, Trillo L, De Miguel Z, Das D, Salehi A. The role of NMDA receptors in the pathophysiology and treatment of mood disorders. Neurosci Biobehav Rev. 2014 Nov; 47:336-58.
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Ghasemi M, Kazemi MH, Yoosefi A, Ghasemi A, Paragomi P, Amini H, Afzali MH. Rapid antidepressant effects of repeated doses of ketamine compared with electroconvulsive therapy in hospitalized patients with major depressive disorder. Psychiatry Res. 2014 Feb 28; 215(2):355-61.
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Louderback KM, Wills TA, Muglia LJ, Winder DG. Knockdown of BNST GluN2B-containing NMDA receptors mimics the actions of ketamine on novelty-induced hypophagia. Transl Psychiatry. 2013 Dec 03; 3:e331.
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Yosipovitch G, Bernhard JD. Clinical practice. Chronic pruritus. N Engl J Med. 2013 Apr 25; 368(17):1625-34.