"Receptor, Adenosine A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
| Descriptor ID |
D043682
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.100 D12.776.543.750.720.700.700.100
|
| Concept/Terms |
Receptor, Adenosine A1- Receptor, Adenosine A1
- Adenosine A1 Receptors
- Receptors, Adenosine A1
- Adenosine A1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.695.700.700.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.720.700.700.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A1".
This graph shows the total number of publications written about "Receptor, Adenosine A1" by people in this website by year, and whether "Receptor, Adenosine A1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Adenosine A1" by people in Profiles.
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Komatsu S, Dobson JG, Ikebe M, Shea LG, Fenton RA. Crosstalk between adenosine A1 and ?1-adrenergic receptors regulates translocation of PKCe in isolated rat cardiomyocytes. J Cell Physiol. 2012 Sep; 227(9):3201-7.
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Fenton RA, Shea LG, Doddi C, Dobson JG. Myocardial adenosine A(1)-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1671-8.
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Fenton RA, Komatsu S, Ikebe M, Shea LG, Dobson JG. Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H718-25.
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Dobson JG, Shea LG, Fenton RA. Adenosine A2A and beta-adrenergic calcium transient and contractile responses in rat ventricular myocytes. Am J Physiol Heart Circ Physiol. 2008 Dec; 295(6):H2364-72.
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Tikh EI, Fenton RA, Chen JF, Schwarzschild MA, Dobson JG. Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart. J Cell Physiol. 2008 Jul; 216(1):83-90.
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Fenton RA, Dobson JG. Adenosine A1 and A2A receptor effects on G-protein cycling in beta-adrenergic stimulated ventricular membranes. J Cell Physiol. 2007 Dec; 213(3):785-92.
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Perlini S, Arosio B, Parmeggiani L, Santambrogio D, Palladini G, Tozzi R, Gatti C, Annoni G, Meyer TE, Ferrari AU. Adenosine A1 receptor expression during the transition from compensated pressure overload hypertrophy to heart failure. J Hypertens. 2007 Feb; 25(2):449-54.
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Knott TK, Marrero HG, Fenton RA, Custer EE, Dobson JG, Lemos JR. Endogenous adenosine inhibits CNS terminal Ca(2+) currents and exocytosis. J Cell Physiol. 2007 Feb; 210(2):309-14.
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Ethier MF, Madison JM. Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells. Am J Respir Cell Mol Biol. 2006 Oct; 35(4):496-502.
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Tikh EI, Fenton RA, Dobson JG. Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts. Am J Physiol Heart Circ Physiol. 2006 Jan; 290(1):H348-56.