Receptor, Serotonin, 5-HT2C
"Receptor, Serotonin, 5-HT2C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.
| Descriptor ID |
D044405
|
| MeSH Number(s) |
D12.776.543.750.670.800.200.200 D12.776.543.750.695.800.200.200 D12.776.543.750.720.850.200.200
|
| Concept/Terms |
Receptor, Serotonin, 5-HT2C- Receptor, Serotonin, 5-HT2C
- 5-HT2C Receptor
- 5 HT2C Receptor
- Receptor, 5-HT2C
- 5-Hydroxytryptamine Type 2C Receptor
- 5 Hydroxytryptamine Type 2C Receptor
- Receptor, 5-Hydroxytryptamine Type 2C
- Receptor, 5 Hydroxytryptamine Type 2C
- Serotonin 2C Receptor
- Receptor, Serotonin 2C
- 5-HT(2C) Receptor
- 5-Hydroxytryptamine Type 2C Receptors
- 5 Hydroxytryptamine Type 2C Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2C".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.670.800.200.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.695.800.200.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.720.850.200.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2C".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2C" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2C" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2C" by people in Profiles.
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Nakamura S, Sasaki T, Uenoyama Y, Inoue N, Nakanishi M, Yamada K, Morishima A, Suzumura R, Kitagawa Y, Morita Y, Ohkura S, Tsukamura H. Raphe glucose-sensing serotonergic neurons stimulate KNDy neurons to enhance LH pulses via 5HT2CR: rat and goat studies. Sci Rep. 2024 05 03; 14(1):10190.
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Bonasera SJ, Schenk AK, Luxenberg EJ, Wang X, Basbaum A, Tecott LH. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PLoS One. 2015; 10(12):e0142906.
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Assetta B, Maginnis MS, Gracia Ahufinger I, Haley SA, Gee GV, Nelson CD, O'Hara BA, Allen Ramdial SA, Atwood WJ. 5-HT2 receptors facilitate JC polyomavirus entry. J Virol. 2013 Dec; 87(24):13490-8.
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Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, Esposito E, Parsons LH, Bonci A, Tecott LH. Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. J Neurosci. 2009 Jun 24; 29(25):8156-65.
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Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. J Med Chem. 2003 Jul 31; 46(16):3526-35.
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Nonogaki K, Abdallah L, Goulding EH, Bonasera SJ, Tecott LH. Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice. Diabetes. 2003 Feb; 52(2):315-20.
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Chambers JJ, Kurrasch-Orbaugh DM, Nichols DE. Translocation of the 5-alkoxy substituent of 2,5-dialkoxyarylalkylamines to the 6-position: effects on 5-HT(2A/2C) receptor affinity. Bioorg Med Chem Lett. 2002 Aug 05; 12(15):1997-9.